5篇
您的检索式：作者名="Carina Graversen"
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| 1 | Translational aspects of rectal evoked potentials: a comparative study in rats and humans显示文摘 | Thomas Dahl Nissen Christina Brock Carina Graversen Steven J. Coen Leif Hultin Qasim Aziz Jens Lykkesfeldt Asbj?rn Mohr Drewes | 2013 | AJP: Gastrointestinal and Liver Physiology2013，，2： | 1 |
| 2 | Pharmacological pain management in chronic pancreatitis显示文摘Intense abdominal pain is a prominent feature of chronic pancreatitis and its treatment remains a major clinical challenge.Basic studies of pancreatic nerves and experimental human pain research have provided evidence that pain processing is abnormal in these patients and in many cases resembles that seen in neuropathic and chronic pain disorders.An important ultimate outcome of such aberrant pain processing is that once the disease has advanced and the pathophysiological processes are firmly established,the generation of pain can become self-perpetuating and independent of the initial peripheral nociceptive drive.Consequently,the management of pain by traditional methods based on nociceptive deafferentation(e.g.,surgery and visceral nerve blockade)becomes difficult and often ineffective.This novel and improved understanding of pain aetiology requires a paradigm shift in pain management of chronic pancreatitis.Modern mechanism based pain treatments taking into account altered pain processing are likely to increasingly replace invasive therapies targeting the nociceptive source,which should be reserved for special and carefully selected cases.In this review,we offer an overview of the current available pharmacological options for pain management in chronic pancreatitis.In addition,future options for pain management are discussed with special emphasis on personalized pain medicine and multidisciplinarity. | Sφren S Olesen Jacob Juel Carina Graversen Yuri Kolesnikov Oliver HG Wilder-Smith Asbjφrn M Drewes | 2013 | World Journal of Gastroenterology2013，19，42： | 1 |
| 3 | Slowed EEG rhythmicity in patients with chronic pancreatitis: evidence of abnormal cerebral pain processing?显示文摘 | S?ren S. Olesen Tine M. Hansen Carina Graversen Kristoffer Steimle Oliver H.G. Wilder-Smith Asbj?rn Mohr Drewes | 2011 | European Journal of Gastroenterology & Hepatology2011，，5： | 1 |
| 4 | Slowed EEG rhythmicity in patients with chronic pancreatitis: evidence of abnormal cerebral pain processing?显示文摘 | S?ren S. Olesen Tine M. Hansen Carina Graversen Kristoffer Steimle Oliver H.G. Wilder-Smith Asbj?rn Mohr Drewes | 2011 | European Journal of Gastroenterology & Hepatology2011，，5： | 1 |
| 5 | Electrophysiology as a tool to unravel the origin of pancreatic pain显示文摘Intense abdominal pain is the most common symptom in chronic pancreatitis, but the underlying mechanisms are not completely understood and pain management remains a significant clinical challenge.The focus of pain origin in chronic pancreatitis traditionally has been on the pancreatic gland, assuming pain to originate in the pancreas or its surrounding organs. However, research in the last decade points to abnormal central nervous system pain processing.For this reason, electroencephalography has been receiving increasing attention. In contrast to imaging methods such as functional magnetic resonance and positron emission tomography, electroencephalogram has excellent temporal resolution making it possible to investigate central processing of pain on a millisecond time scale. Moreover, continuously advancing methodology made it possible to explore brain sources responsible for generation of evoked potentialsand hence to study brain reorganization due to pain in chronic pancreatitis. The aim of this review is to give an overview of the current methods and findings in electroencephalography as a tool to unravel the origin of pancreatic pain. | Dina Lelic Sφren Schou Olesen Carina Graversen Christina Brock Massimiliano Valeriani Asbjφrn Mohr Drewes | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，1： | 0 |
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