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| 1 | Platelets in hemostasis and thrombosis:Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis显示文摘Platelets are small anucleate cells generated from megakaryocytes in the bone marrow.Although platelet generation,maturation,and clearance are still not fully understood,significant progress has been made in the last 1-2 decades.In blood circulation,platelets can quickly adhere and aggregate at sites of vascular injury,forming the platelet plug(i.e.the first wave of hemostasis).Activated platelets can also provide negatively charged phosphatidylserinerich membrane surface that enhances cell-based thrombin generation,which facilitates blood coagulation(i.e.the second wave of hemostasis).Platelets therefore play central roles in hemostasis.However,the same process of hemostasis may also cause thrombosis and vessel occlusion,which are the most common mechanisms leading to heart attack and stroke following ruptured atherosclerotic lesions.In this review,we will introduce the classical mechanisms and newly discovered pathways of platelets in hemostasis and thrombosis,including fibrinogen-independent platelet aggregation and thrombosis,and the plasma fibronectin-mediated 'protein wave' of hemostasis that precedes the classical first wave of hemostasis.Furthermore,we briefly discuss the roles of platelets in inflammation and atherosclerosis and the potential strategies to control atherothrombosis. | Yan Hou Naadiya Carrim Yiming Wang Reid C.Gallant Alexandra Marshall Heyu Ni | 2015 | The Journal of Biomedical Research2015，29，6： | 21 |
| 2 | The efficacy of 5% povidone-iodine for 3 minutes prior to cataract surgery显示文摘 | Carrim Z I Mackie G Gallacher G | 2009 | Eur J Ophthalmol2009，19，4： | 1 |
| 3 | The efficacy of 5%pov-idone-iodine for 3 minutes prior to cataract surgery显示文摘 | Carrim ZI Mackie G Gallacher G | 2009 | Eur J Oph-thalmol2009，19，4： | 1 |
| 4 | Diaton tonometry: an assessment of validity and preference against Goldmann tonometry 显示文摘 | Doherty MD Carrim ZI O'Neill DP | 2012 | Clin Experiment Ophthalmol2012，40，4： | 1 |
| 5 | Diaton tonometry: an assessment of validity and preference against Goldmann tonometry显示文摘 | DOHERTY MD CARRIM ZI O'NEILL DP | 2012 | Clin Experiment Ophthalmol2012，40，4： | 1 |
| 6 | Punctoplasty with a Kel- ly punch显示文摘 | Carrim ZI Liolios VI Vize CJ | 2011 | Ophthal Plast Reconstr Surg2011，27，： | 1 |
| 7 | Traumatic arteri- ovenous fistula : experience with 202 patients显示文摘 | Robbs J Carrim AA Kadwa AM | 1994 | Br J Surg1994，81，9： | 1 |
| 8 | Traumatic arteriovenous fistula: experience with 202 patients显示文摘 | Robbs J V Carrim A A Kadwa A M | 1994 | Br J Surg1994，81，9： | 1 |
| 9 | Predicting impairment of central vision from dimensions of the optic chiasm in patients with pituitary adenoma显示文摘 | Carrim ZI Reeks GA Chohan AW | 2007 | Acta Neurochir (Wien)2007，149，： | 1 |
| 10 | The efficacy of 5% providone-iodine for 3 minutes prior to cataract surgery显示文摘 | Carrim ZI Mackie G Gallacher G | 2009 | Eur J Ophthal2009，19，： | 1 |
| 11 | 10-Minute Consultation Chalazion显示文摘 | Esmaeil M Arbabi Ross J Kelly Zia I Carrim | 2010 | 英国医学杂志中文版2010，13，5： | 1 |
| 12 | Predicting impair- ment of central vision from dimensions of the optic chiasm in patients with pituitary adenoma 显示文摘 | Carrim ZI Reeks GA Chohan AW | 2007 | Acta Neurochir (Wien)2007，149，3： | 1 |
| 13 | Colour-flow ultrasound in the detection of penetrating vascular injuries of the neck显示文摘 | Corr P Abdool Carrim AT Robbs J | 1999 | S Afr Med J1999，89，6： | 1 |
| 14 | The relationship between stress and acute anterior uveitis显示文摘 | Carrim ZI Ahmed TY Taguri AH | 2006 | Acta Ophthalmol Scand2006，84，： | 1 |
| 15 | The efficacy of 5 % povidone-iodine for 3 minutes prior to cataract surgery显示文摘 | CARRIM Z I MACKIE G GALLACHER G | 2009 | Eur J Ophthalmol2009，19，4： | 1 |
| 16 | The Prevalence of Simple Renal and Hepatic Cysts Detected by Spiral Computed Tomography显示文摘 | Z.I. Carrim J.T. Murchison | 2003 | Clinical Radiology2003，，8： | 1 |
| 17 | The efficacy of 5% povidone-iodine for 3 minutes prior toeataraetsurgery 显示文摘 | Carrim ZI Mackie G Gallacher G | 2009 | Eur J Ophthalmol2009，19，： | 1 |
| 18 | The role of Noxl and Nox2 in GP V显示文摘 | Walsh TG Berndt MC Carrim N | 2014 | Redox Biol2014，2，34： | 1 |
| 19 | Management of proximal axillary and subclavian artery injuries显示文摘 | Mckinley AG Carrim AT Robbs JV | 2000 | The British Journal of Surgery2000，87，1： | 1 |
| 20 | Inclusiveness and participation in discourses of educational governance in South Africa显示文摘 | Yusuf Sayed Nazir Carrim | 1998 | International Journal of Inclusive Education1998，，1： | 1 |
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