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| 1 | Strongyloides hyper-infection causing life-threatening gastrointestinal bleeding显示文摘A 55-year old male patient was diagnosed with strongy- loides hyper-infection with stool analysis and intestinal biopsy shortly after his chemotherapy for myeloma. He was commenced on albendazole anthelmintic therapy. After initiation of the treatment he suffered life- threatening gastrointestinal (GI) bleeding. Repeated endoscopies showed diffuse multi-focal intestinal bleeding. The patient required huge amounts of red blood cells and plasma transfusions and correction of haemostasis with recombinant activated factor Ⅶ. Abdominal aorto-angiography showed numerous micro- aneurysms (‘berry aneurysms’) in the superior and inferior mesenteric arteries’ territories. While the biopsy taken prior to the treatment with albendazole did not show evidence of vasculitis, the biopsy taken after initiation of therapy revealed leukoclastic aggregations around the vessels. These findings suggest that, in addition to direct destruction of the mucosa, vasculitis could be an important additive factor causing the massive GI bleeding during the anthelmintic treatment. This might result from substances released by the worms that have been killed with anthelmintic therapy. Current guidelines advise steroids to be tapered and stopped in case of systematic parasitic infections as they might reduce immunity and precipitate parasitic hyper-infection. In our opinion, steroid therapy might be of value in the management of strongyloides hyper- infection related vasculitis, in addition to the anthelmintic treatment. Indeed, steroid therapy of vasculitis with other means of supportive care resulted in cessation of the bleeding and recovery of the patient. | Lajos Csermely Hassan Jaafar Jorgen Kristensen Antonio Castella Waldemar Gorka Ahmed Ali Chebli Fawaz Trab Hussain Alizadeh Béla Hunyady | 2006 | World Journal of Gastroenterology2006，12，39： | 1 |
| 2 | Estrogens and men with schizophrenia:is there a case for adjunctive therapy? 显示文摘 | Kolkarni J de Castella A Headey B | 2011 | Schizophrenia Research2011，125，： | 1 |
| 3 | Estrogens and men with schizophrenia:is there a ease for adjunctive therapy 显示文摘 | Kulkarni J de Castella A Headey B | 2011 | Schizophr Res2011，125，23： | 1 |
| 4 | The prognostic value of BRCA1 mRNA expression levels following neoadjuvant chemotherapy in breast cancer显示文摘 | MARGELI M CIRAUQUI B CASTELLA E | 2010 | PLoS One2010，5，3： | 1 |
| 5 | Two new lipid-de- pendent Malassezia species from domestic animals 显示文摘 | Cabafies FJ Theelen B Castella G | 2007 | FEMS Yeast Res2007，7，6： | 1 |
| 6 | A randomized, controlled trial of sequential bilateral repetitive transcranial magnetic stimulation for treatment-resistant depression显示文摘 | Fitzgerald P B Benitez J de Castella A | 2006 | Am J Psychiatry2006，163，1： | 1 |
| 7 | The prognostic value of BRCA1 mRNA expression levels following neoadjuvant chemotherapy in breast cancer显示文摘 | Margeli M Cirauqui B Castella E | 2010 | PLoS One2010，5，3： | 1 |
| 8 | Optimisation of Narrow Face Water Slot Design for Siderar Slab Casting Mould 显示文摘 | Thomas B G Langeneckert M Castella L | 2003 | Ironmaking and Steelmaking2003，30，3： | 1 |
| 9 | Does size matter? Therelationship between pond area and biodiversity显示文摘 | OERTLI B JOYE D A CASTELLA E | 2002 | BiologicalConservation2002，104，1： | 1 |
| 10 | An autocrine cy- tokine/JAK/STAT-signaling induces kynurenine synthesis in multidrug resistant human cancercells显示文摘 | Campia I Buondonno I Castella B | 2015 | PLoS One2015，10，01： | 1 |
| 11 | Two new lipid-dependent Malassezia species from domestic animals显示文摘 | Cabanes FJ Theelen B Castella G | 2007 | FEMS Yeast Res2007，7，6： | 1 |
| 12 | Two new lipid-dependent Malassezia species from domestic animals 显示文摘 | Cabanes FJ Theelen B Castella G | 2007 | FEMS Yeast Res2007，7，6： | 1 |
| 13 | Two new lipid-dependent Malassezia spe?cies from domestic animals显示文摘 | Cabanes FJ Theelen B Castella G | 2007 | FEMS Yeast Res2007，7，6： | 1 |
| 14 | Optimization of narrow face water slot design for Siderar slab casting mould显示文摘 | THOMAS B G LANGENECKERT M CASTELLA L DZIUBA M GRESIA G D BALANTE W | 2003 | Ironmaking and Steelmaking2003，30，3： | 1 |
| 15 | Macroinvertehrate communitystructure in relation to environmental variables in a Swiss glacial stream 显示文摘 | Lods-Crozet B Castella E Cambin D | 2001 | Freshwater Biology2001，46，： | 1 |
| 16 | The prognostic value ofBRCA1 mRNA expression levels following neoadjuvant chemother-apy in breast cancer显示文摘 | Margeli M Cirauqui B Castella E | 2010 | PLoS 0ne2010，5，3： | 1 |
| 17 | The prognostic value of BRCA1 mRNA expression levels following neoadjuvant chemotherapy in breast cancer显示文摘 | Margeli M Cirauqui B Castella E | 2010 | PLoS One2010，5，3： | 1 |
| 18 | Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vgamma9Vdelta2 T cells, alphabeta CDS(-{-) T cells, regulatory T cells, and dendritic cells显示文摘 | Castella B Riganti C Fiore F | 2011 | J Immunol2011，187，4： | 1 |
| 19 | The prognostic value of BRCA1 mRNA expression levels following neoadjuvant chemotherapy in breast cancer显示文摘 | Margeli M Cirauqui B Castella E | | 0，，03： | 1 |
| 20 | Estrogens and men with schizophrenia:is there a case for adjunctive therapy显示文摘 | Kulkarni J de Castella A Headey B | | 0，，2： | 1 |
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