|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A robust procedure for Gaussian graphical model search from microarray data with p larger than n显示文摘 | Castelo R Roverato A | | 0，，： | 1 |
| 2 | Splice site identification by idlBNs显示文摘 | CASTELO R GUIGO R | 2004 | Bioinformatics2004，20，1： | 1 |
| 3 | Improving markov chain monte carlo model search for data mining 显示文摘 | GIUDICI P CASTELO R | 2003 | Machine Learning2003，50，12： | 1 |
| 4 | Distinct regulatory pro- grams establish widespread sex-specific alternative splicing in Dro- sophila melanogaster显示文摘 | Hartmann B Castelo R Mi~ana B | 2011 | RNA2011，17，3： | 1 |
| 5 | Immunological fea- tures of the non-structural proteins of porcine reproductive and respiratory syndrome virus显示文摘 | Castelo E R Estrella A B Mateu E | 2015 | Viruses2015，7，3： | 1 |
| 6 | Disturbance Rejection on AMBs by Cascade Controllers 显示文摘 | Garcia R F Castelo J P Pazos A P | 2007 | : 192 - 1972007，，： | 1 |
| 7 | Luteal estradiol pre- treatment coordinates follicular growth during controlled ovarian hyperstimulation with GnRH antagonists 显示文摘 | Fanchin R Salomon L Castelo - Branco A | 2003 | Hum Reprod2003，18，12： | 1 |
| 8 | Splice site identification by idl BNs显示文摘 | Castelo R GuigóR | 2004 | Bioinfor-matics2004，20，1： | 1 |
| 9 | Improving Markov Chain Monte Carlo Model Search for Data Mining显示文摘 | Castelo R | 2003 | Machine Learning2003，50，12： | 1 |
| 10 | TROLL-tandem repeat occurrence locator显示文摘 | CASTELO A T Martins W Gao G R | 2002 | Bioinformatics2002，18，： | 1 |
| 11 | Comparison of splice sites in mammals and chicken 显示文摘 | Abril J F Castelo R Guigo R | 2005 | Genome Res2005，15，1： | 1 |
| 12 | Improving markov chain monte carlo model search for data mining 显示文摘 | Castelo R | 2003 | Machine Learning2003，50，： | 1 |
| 13 | Improving Markov Chain Monte Carlo Model Search for Data Mining显示文摘 | Giudici P Castelo R | 2003 | Machine Learning2003，50，12： | 1 |
| 14 | Liver transplant in patients with primary sclerosing cholangitis:A retrospective cohort from Northeastern Brazil显示文摘BACKGROUND Primary sclerosing cholangitis(PSC)manifests within a broad ethnic and racial spectrum,reflecting different levels of access to health care.AIM To evaluate the clinical profile,complications and survival rates of patients with PSC undergoing liver transplantation(LTx)at a Brazilian reference center.METHODS All patients diagnosed with PSC before or after LTx were included.The medical records were reviewed for demographic and clinical variables,including outcomes and survival.The level of statistical significance was set at P<0.05.RESULTS Our cohort represented 1.6%(n=34)of the 2113 patients receiving liver grafts at our service over the past two decades.Most were male(n=19;56%).The average age(40±14 years)was similar for men and women(P=0.347).The mean follow-up time from diagnosis to LTx was 68 mo.Most patients had the classic form of PSC.Three women had PSC/autoimmune hepatitis overlap syndrome,and one patient had small-duct PSC.Alkaline phosphatase levels at diagnosis and pre-LTx model for end-stage liver disease.scores were significantly higher in males.Inflammatory bowel research(IBD)was investigated by colonoscopy in 26/34(76%)and was present in most cases(18/26;69%).IBD was less common in women than in men(44.4%vs.55.6%)(P=0.692).Cholangiocarcinoma(CCA)was diagnosed in 2/34(5.9%)patients by histopathology of the explant(survival:3 years 6 mo,and 4 years 11 mo).Two patients had complications requiring a second LTx(one after 7 d due to hepatic artery thrombosis and one after 17 d due to primary graft dysfunction).Five patients(14.7%)developed biliary stricture.The overall median post-LTx survival was 66 mo.Most deaths occurred in the first year(infection n=2,primary liver graft dysfunction n=3,unknown cause n=1).The 1-year and 5-year survival rates of this cohort were 82.3%and 70.6%,respectively,matching the mean overall survival rates of LTx patients at our center(87.1%and 69.43%,respectively)(P=0.83).CONCLUSION Survival after 1 and 5 years was similar to that of other LTx indications.The observed CCA survival rate suggests CCA may be an indication for LTx in selected cases. | Louyse Teixeira de Souza Freitas Elodie Bomfim Hyppolito Victor Leonardo Barreto Luiz Humberto JataíCastelo Júnior Bianca Carneiro de Melo Jorge Frederico César Tahim de Sousa Brasil Háteras Malthus Barbosa Marzola Clébia Azevedo Lima Raquel Mendes Celedonio Gustavo Rêgo Coelho Jose Huygens Parente Garcia | 2023 | World Journal of Hepatology2023，15，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员