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| 1 | Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a frequently reported condition in patients with inflammatory bowel disease(IBD).Both intestinal inflammation and metabolic factors are believed to contribute to the pathogenesis of IBDassociated NAFLD.AIM To evaluate the prevalence of steatosis and liver fibrosis(LF)in a cohort of IBD patients and the identification of metabolic-and IBD-related risk factors for NAFLD and LF.METHODS IBD patients were consecutively enrolled from December 2016 to January 2018.Demographic,anthropometric and biochemical data were collected so as eating habits.Abdominal ultrasound and transient elastography were performed to evaluate the presence of NAFLD and LF respectively.RESULTS A total of 178 consecutive patients were enrolled and included in the analysis(95 Ulcerative colitis,83 Crohn’s disease).NAFLD was detected by imaging in 72(40.4%)patients.Comparison between patients with and without NAFLD showed no significant differences in terms of IBD severity,disease duration,location/extension,use of IBD-related medications(i.e.,steroids,anti-TNFs,and immunomodulators)and surgery.NAFLD was significantly associated with the presence of metabolic syndrome[MetS;odds ratio(OR):4.13,P=0.001]and obesity defined by body mass index(OR:9.21,P=0.0002).IBD patients with NAFLD showed higher caloric intake and lipid consumption than those without NAFLD,regardless disease activity.At the multivariate analysis,male sex,advanced age and high lipid consumption were independent risk factors for the development of NAFLD.An increased liver stiffness was detected in 21 patients(16%)and the presence of MetS was the only relevant factor associated to LF(OR:3.40,P=0.01).CONCLUSION In this study,we demonstrate that risk factors for NAFLD and LF in the IBD population do not differ from those in the general population. | Salvatore Magrì Danilo Paduano Fabio Chicco Arianna Cingolani Cristiana Farris Giovanna Delogu Francesca Tumbarello Mariantonia Lai Alessandro Melis Laura Casula Massimo C Fantini Paolo Usai | 2019 | World Journal of Gastroenterology2019，25，37： | 8 |
| 2 | Outcomes for early rectal cancer managed with transanal endoscopic microsurgery显示文摘 | F. Stipa A. Burza G. Lucandri M. Ferri A. Pigazzi V. Ziparo G. Casula S. Stipa | 2006 | Surgical Endoscopy2006，，4： | 2 |
| 3 | JAMA Neurol:小脑间歇性θ-脉冲刺激改善卒中患者步态和平衡功能障碍显示文摘卒中后肢体功能障碍会引起步态和平衡功能受损,而步态和平衡障碍是不良功能预后的决定性因素之一。因为步态是独立生活的关键因素,改善步行功能是卒中康复的主要目标。平衡功能障碍对功能独立性和机体整体恢复也有重要影响。然而,卒中患者的步态康复仍然缺乏先进的康复方案。恢复期,对侧小脑参与到卒中后运动网络的功能重组,并发挥重要作用。在卒中动物模型中,刺激小脑皮层网络能够改善功能恢复。值得注意的是,fMRI研究显示对侧小脑神经活性与卒中患者的步态恢复呈正相关。 | 杨中华 KOCH G BONNì S CASULA E P | 2019 | 中国卒中杂志2019，14，9： | 2 |
| 4 | Comparison of the historic seismicity and strain-rate pattern from a dense GPS-GNSS network solution in the Italian Peninsula显示文摘We present a dense crustal velocity field and corresponding strain-rate pattern computed using Global Positioning System(GPS)- Global Navigation Satellite System(GNSS) data from several hundred permanent stations in the Italian Peninsula. GPS data analysis is based on the GAMIT/GLOBK 10.6 software, which was developed and maintained mainly by Massachusetts Institute of Technology(MIT), using tools based on the distributed-sessions approach implemented in this package. The GPS data span the period from January 2008 to December 2012 and come from several different permanent GPS networks in Italy. The GLOBK package implemented in the last version of the GAMIT package is used to compute the position time-series and velocities registered in the International Terrestrial Reference Frame(ITRF) 2008. The resulting high-density intra-plate velocity field provides indications of the tectonics of the Mediterranean region. A computation of the strain-rate pattern from GPS data is performed and compared with the map of the epicentral locations of historical earthquakes that occurred in the last 1000 years in the Italian territory, showing that, in general, higher crustal deformation rates are active in regions affected by seismicity of greater magnitude. | Giuseppe Casula Maria Giovanna Bianchi | 2016 | Geodesy and Geodynamics2016，7，5： | 2 |
| 5 | Bacillus subtilis spores competitively exclude Escherichia coli O78:K80 in poultry显示文摘 | LA RAGIONE R M CASULA G CUTTING S M | 2001 | Vet Microbiol2001，79，2： | 1 |
| 6 | Serum neopterin and soluble interlekin-2 receptor for prediction of a shock state in gram-negative sepsis显示文摘 | Delogu G Casula M A Maneini P | 1995 | J Crit Care1995，10，2： | 1 |
| 7 | Data analysis of permanent GPS networks in Italy and surrounding regions:application of a distributed processing approach显示文摘 | Enrico Serpelloni Giuseppe Casula Alessandro Galvani Marco Anzidei Paolo Baldi | 2006 | Annals of Geophysics2006，49，45： | 1 |
| 8 | An RP-HPLC determination of 5-hydroxymethylfurfural in honey显示文摘 | Nadia Spano Lucia Casula Angelo Panzanelli Maria I. Pilo Paola C. Piu Roberta Scanu Andrea Tapparo Gavino Sanna | 2005 | Talanta2005，，4： | 1 |
| 9 | Clinical ability of Heidelberg retinal tomograph examination to detect glaucomatous visual field changes显示文摘 | Miglior S Casula M Guareschi M | 2001 | Ophthalmology2001，108，9： | 1 |
| 10 | Off-pump myocardial revascularization is associated with less incidence of stroke in elderly patients显示文摘 | Thanos Athanasiou Sharif Al-Ruzzeh Pankaj Kumar Mary-Clare Crossman Mohamed Amrani John R Pepper Rex Del Stanbridge Roberto Casula Brian Glenville | 2004 | The Annals of Thoracic Surgery2004，，2： | 1 |
| 11 | Confined growth of iron cobalt nanocrystals in mesoporous silica thin film: FeCo-SiO2 nanocomposites 显示文摘 | Stefano Costacurta Luca Malfatti Plinio Innocenzi Heinz Amenitsch Alice Masili Anna Corrias Maria Francesca Casula | 2008 | Microporous and Mesoporous Materials2008，115，33： | 1 |
| 12 | Clinical ability of Heidelberg retinal tomograph examination to detect glaucomatous visual field changes 显示文摘 | Miglior S Casula M Guareschi M | 2001 | Ophthalmology2001，108，9： | 1 |
| 13 | Data Analysis of Permanent GPS Networks in Ltaly and Surrounding Regions: Application of A Aistributed Processing Approach 显示文摘 | ENRICO SERPELLONI GIUSEPPE CASULA ALESSANDRO GALVANI | 2006 | Annals of Geophysics2006，49，45： | 1 |
| 14 | Network of superconducting gravimeters benefits a number of disciplines显示文摘 | Crossley D Hinderer J Casula G | 1999 | EOS1999，80，12： | 1 |
| 15 | Clinical ability of Heidelberg retinal tomograph examinationto detect glaucomatous visual field changes显示文摘 | Miglior S Casula M Guareschi M Marchetti I Lester M OrzalesiN | 2001 | Ophthalmolo-gy2001，108，9： | 1 |
| 16 | Infection with HIV-1 induces a decrease in mtDNA显示文摘 | Casula M Bosboom-Dobbelaer I Smolders K | 2005 | J Infect Dis2005，191，9： | 1 |
| 17 | Mechanical ventilation modu- lates Toll-like receptor signaling pathway in a sepsis-induced lung injury model显示文摘 | Villar J Cabrera N Casula M | 2010 | Intensive Care Med2010，36，6： | 1 |
| 18 | Control of complex components with Smart Flexible Phased Arrays显示文摘 | O. Casula C. Poidevin G. Cattiaux Ph. Dumas | 2006 | Ultrasonics2006，，： | 1 |
| 19 | Preparation and characterization of FeCo-A1203 and A1203 aerogels显示文摘 | Anna Corrias Casula Maria F | 2004 | Journal of sol-gel science and technology2004，31，： | 1 |
| 20 | Flexible and array eddy current probes for fast inspection of com- plex parts 显示文摘 | MARCHAND B DECITRE J M CASULA O | 2010 | Review of Quantitative Nondesrtructive Evalution2010，9，： | 1 |
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