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您的检索式：作者名="Catherine Gunawan"
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| 1 | The risk factors of SARS-CoV-2 antibody level differences in healthcare workers post vaccination in Siloam hospitals:A nationwide multicenter study显示文摘Background:Several vaccines have been approved against COVID-19,and 5 have been used in Indonesia.Due to the decrease in antibody levels 3 to 6 months after the second dose of CoronaVac,healthcare workers received the third booster of mRNA vaccine(mRNA-1273)to increase the antibody level.This study aimed to evaluate the risk factors of anti-S-RBD IgG levels differences in healthcare workers.Methods:This study is a retrospective cohort study of 576 healthcare workers without previous SARS-CoV-2 infection who received 2 doses of CoronaVac and the third dose of mRNA-12736 months after the second dose.Blood samples were obtained 2nd,6th,12th,and 24th weeks after the second dose of CoronaVac vaccine administration,with mRNA-1273 booster on week 20.Quantitative measurements of IgG antibodies were performed with Elecsys Anti-SARS-CoV-2 S immunoassay.We identify the baseline factors predicting post-vaccination antibody titers using univariate and multivariate linear regression analysis.Results:This study comprised 576 participants aged 32 years old,72.05%female,and 45.84%from high-risk occupation subgroups.The median antibodies titer level on the 2nd,6th,12th,and 24th weeks after the second vaccine dose administration were 40.99 u/mL,42.01 u/mL,54.78 u/mL,and 23,225 u/mL.Antibody levels trended highest in female and younger age group(20-29 years old).Conclusions:The third dose of vaccine increased the quantitative SARS-CoV-2 spike IgG antibody titers and eliminated differences in antibodies titer by gender. | Allen Widysanto Ignatius Bima Prasetya Tandry Meriyanti Veli Sungono Diane Lukito Setiawan Edy Gunawan Bayu Adiputra Jane Olivia Lorens Theresia Santi Cindy Meidy Leony Pradhana Irawan Yusuf Catherine Gunawan | 2022 | Infectious Medicine2022，1，4： | 0 |
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