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| 1 | Preface显示文摘Kaschin-Beck disease (KBD) is regarded as an endemic, chronic, high incidence and degenerative osteoarthropathie disease. The areas of endemic KBD are relatively stable and are correlated with specific geographical environments. In China, estimation of KBD patients in 1985 indicated more than 2 million people were severely affected in a broad region inhibited by over 30 million people. KBD endemic areas form a broad belt extending from northeast to southwest. The disease mostly appears in mountainous and hilly regions, and farmers are the major potentially affected ones. Hence KBD has been designated a national health priori-ty problem in China since 60’s. | Peng AnProfessor Research Center for Eco-Environmental Sciences,Chinese Academy o Sciences | 1991 | Journal of Environmental Sciences1991，3，4： | 5 |
| 2 | Oligomeric Procyanidins Induce Generation of Reactive Oxygen Species and Collapse of Mitochchondrial Membrane Potential in Glioblastoma Cell Lines显示文摘Objective The aim of the present study was to clarify the mechanism underlying glioma cell death upon oligomeric procyanidins (F2) exposure. Methods The cytotoxicity of F2 on U87 (human malignant glioblastoma cell line) and C6 (rat glioma cell line) cancer cells was evaluated, and changes of mitochondrial membrane potential (MMP) and production of reactive oxygen species (ROS) in drug-treated cells were monitored. Moreover, morphological changes associated with F2-induced cells death were examined. Results F2 induced a concentration-dependent increase in ROS production and decrease in MMP. Furthermore, pre-incubation with N-acetylcysteine (NAC) and rotenone (Rt), resulted in partial inhibition of F2-induced ROS generation and marked attenuation of cell death and the cytoplasmic vacuolization induced by F2. In addition, pretreatment with Rt markedly attenuated the MMP loss in F2-treated cells. However, pretreatment with NAC only markedly attenuated the MMP loss in F2-treated C6 cells. Conclusion The increase in ROS level is at least one of mechanisms associated with F2-induced glioma cell death as well as the cytoplasmic vacuolization formation that contribute to the cytotoxicity of F2 in glioma cells. | ZHANG Feng-jiao1, YANG Jing-yu1, MOU Yan-hua1, SUN Bao-shan2, WANG Ji-ming3, WANG Fang1, WU Chun-fu1 1. Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China 2. Estaco Vitivinícola Nacional, Instituto National de Investigaco Agrária, Dois Portos 2565-191, Portugal 3. Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick Maryland 21702, USA | 2009 | Chinese Herbal Medicines2009，1，1： | 3 |
| 3 | Correlative ionospheric disturbances in the sunlit hemisphere during the flare on July 14,2000显示文摘Using GPS data obtained from GPS sites located on the sunlit hemisphere during the flare on July 14, 2000, the ionospheric response to the flare was analyzed. A kind of tiny correlative ionospheric fluctuations were revealed from the temporal total electron content (TEC) curves derived from GPS measurements, and the values of this kind of disturbances are about 1015 m-2. A comparative analysis of these disturbances and soft X-ray flux detected at GOES satellite during the flare is done. It is found that this kind of disturbances revealed in the temporal TEC curves did occur in a very large area of sunlit ionosphere and its behavior is mainly controlled by the characteristics of the flare’s extra radiation. Because the similar fluctuations are not found in the curve of soft X-ray flux, it is concluded that the flare extra radiation in EUV band should have corresponding fluctuations and it is the fluctuations that cause the TEC disturbances. The height, where the disturbances occur, should be in the F | ZHANG Donghe & XIAO ZuoDepartment of Geophysics, Peking University, Beijing 100871, China Qingdao Research Center, Chinese Research Institute of Radio-wave Propagation, Qingdao 266071, China Center for Space Science and Applied Research, Chinese Academy o | 2002 | Chinese Science Bulletin2002，47，12： | 2 |
| 4 | Comparative study on collision resistance of side structure 显示文摘 | Kiamura O Nagasaki R Center D | 1997 | Marine Technology1997，34，4： | 1 |
| 5 | 0 Database 显示文摘 | National Center for O'NET Development Data Dictionary O'NET 14 | 2009 | Employment Security Commission2009，，： | 1 |
| 6 | International variation in prostate cancer incidence and mortality rates显示文摘 | Center M M Jemal A Lortet-Tieulent J Ward E Ferlay J Brawley O | 2012 | Eur Uurol2012，61，： | 1 |
| 7 | Critical load of sulfur deposition for ecosystemand its application in China显示文摘Current situation of air pollution of China is introduced. Critical loads for 4 types of soil in sensitiveareas of China have been calculated using methods of SSMB, Profile Medel and Magic Medel. Maps of criticalload , sulfur deposition of 1 990 and excee | Zhao Dianwu Zhang Xiaoshan Yang Jianxin(Research Center for Eco-Environrnental Sciences , Chinese Academy of Sceiences, Beijing 100085, China)Mao Jietai(Department of Geophysics, Peking University. Beijing 100871 . China)Xiong Jiling(Guizhou Institute o | 1995 | Journal of Environmental Sciences1995，7，3： | 1 |
| 8 | 显示文摘 | Rybaltovsky A O Oxygen-Deficient Centers In Silica Glasses: A Review Of Their Properties And Structure | 1994 | J Non-Cryst Solids1994，179，： | 1 |
| 9 | An emergy evaluation of the seven years’development of Qianyanzhou ecological experimental station显示文摘IBackgroundofEstablishingQianyanzhouExperimentalStationChinaisacountrywithahugepopulationofl2bilion,yet,itisstilincreasingw... | YAN Maichao Commission for Integrated Survey of Natural Resources, Chinese Academy of Sciences, Beijing 100101 CHINA H T O dum Center for Environmental Policy, Department of Environmental Engineering Sciences, University of Florida, Gainesville, | 1998 | Journal of Geographical Sciences1998，8，3： | 1 |
| 10 | Eytomegalovirus as a cause of morobidity in heart transplantation 显示文摘 | Center O Steel HM Murday AJ | 1996 | Transplantation1996，6，2： | 1 |
| 11 | One share, one vote and the market for corporate control 显示文摘 | S B Grossman O Hart L Center | 1988 | Journal of Financial Economics1988，20，： | 1 |
| 12 | Almandine megacrysts from Yingfengling Cenozoic basalt in Leizhou Peninsula and their parental magma origin显示文摘The garnet megacrysts from Yingfengling basalts are characterlzed by high FeO (>20%), CaO (7.02% -8.16%) and low MgO (5.88%-10.87%). Significant composition variations are observed in these megacrysts, of which Ni, V, Sc, Co, and HREE are positively correlated with their Mg# and Zr, Hf, Ga, Y, Sr, Nb, Zn and LREE-MREE are negatively correlated with Mg#. Megacryst parent magma is a highly evolved residual melt with strongl depletion in Ti, Sr, Hf, Nb and HREE. This parental magma was generated by more than 60% of crystallization fractionation of clinopyroxene, garnet, plagioclase and ilmenite from quartz tholeiitic magma. It has not erupted to the surface, but stayed at the upper mantle and formed the megacrystic cumulate. Megacrysts and their host basalt are in disequilibrium. | YU Jinhai & S. Y. O’Reilly1. National Key Laboratory of Metallogenic Mechanism of Endogenetic Deposits, Department of Earth Sciences, Nanjing University, Nanjing 210093, China 2. National Key Center of GEMOC, Department of Earth and Planetary Sciences, Macquarie University, North Ryde, NSW 2109, Australia | 2001 | Chinese Science Bulletin2001，46，14： | 1 |
| 13 | Comparative study on collision resistance of side structure显示文摘 | Kiamura O Nagasaki R Center D | 1997 | Marine Technol- ogy1997，34，4： | 1 |
| 14 | Cytomegalovirus as a cause of morbidity in heart transplantation 显示文摘 | Center O Steel HM Murday AJ | 1996 | Transplantation1996，6，2： | 1 |
| 15 | Distribution of ionotropic glutamate receptor subunlt mRNAs in the rat hypothalamus显示文摘 | Eyigor O Centers A Jennes L | 2001 | J Comp Neurol2001，434，1： | 1 |
| 16 | Elimination of Uninformative Variables for Multivariate Calibration显示文摘 | CENTER V MASSART D L DENORRD O E | 1996 | Anal Chem1996，68，： | 1 |
| 17 | Water Vapor Variability in the Tropical Western Pacific from 20-year Radiosonde Data显示文摘The 20-year (1976-1995) daily radinsonde data at 17 stations in the tropical western Pacific was ana- lyzed. The analysls shows that the atmosphere is more humid in a warmer climate on seasonal,inter-annual and long-term (20-year) time scales, implying a positive water vapor feedback The vertlcal structure of the long-term trends in relative humidity (RH) is distinct from that on short-term (seasonal and inter-annual) time scales, suggesting that observed water vapor changes on short time scales could not be considered as a surrogate of long-term climate change. The increasing trend of RH (3%-5% / decade) in the upper troposphere is stronger than that in the lower troposphere (1 %-2% / decade). Such verthal structure would amplify positive water vapor feedback in comparison to the common assumption of constant RH changes vertically. The empicical orthogonal function (EOF) analysis of vertical structure of RH varmtions shows distinct features of the vert1cal structure of the first three EOFs. The first three EOFs are optimal for repre- sentation of water vapor profiles and provide some hints on physical mechanisms respons1ble for observed humidity variability. Vaisala radiosondes were used at nine stations, and VIZ radiosondes used at other eight stations The Vaisala data are corrected for temperature-dependence error using the correction siheme developed by NCAR / ATD and Vaisala. The comparison of Vaisala and VIZ data shows that the VIZ-measured RHs after October 1993 have a moist bias of - 10% at RHs < 20%. During 1976-1995, several changes in- cluding both instruments and reporting practice have been made at Vaisala stations and introduce errors to long-term RH variations. | Junhong Wang, Harold L. Cole and David J. Carlson National Center for Atmospheric Research P. O, Box 3000,Boulder, CO 80307 | 2001 | Advances in Atmospheric Sciences2001，18，5： | 0 |
| 18 | Studies on Free Radical EPR, Superoxide Dismutase Water-soluble Lipidperoxide in Tears显示文摘StudiesonFreeRadicalEPR,SuperoxideDismutaseWater┐solubleLipidperoxideinTearsYUANYi*,ZHAOShi-hong,YANGShou,CUIYa-nanandZHAN... | YUAN Yi*, ZHAO Shihong, YANG Shou, CUI Yanan and ZHANG Reixue(Ophthalmic Department, Center Laboratory of the Third Clinical Hospital, Norman Bethune University of Medical Sciences, 130021 Surveying and Determining o | 1998 | Chemical Research in Chinese Universities1998，14，2： | 0 |
| 19 | Dilepton production in baryon-rich quark-gluon matter显示文摘From the full stopping scenario and considered the Drell-Yang background, the rapidity dependence of the dilepton production from the central collision 197Au + 197Au has been studied in the baryon-rich quark-gluon matter by using a relativistic hydrodynamic model.It can be found that the dilepton yield is strongly suppressed as increasing the rapidity. Such a characteristic signaling the formation of the baryon-rich quark-gluon matter can be tested in future experiments at CERN and Brookhaven. | He Ze-Jun Zhang Jia-Ju Jiang Wei-Zhou and Liu Bo (CCAST World Laboratory P. O. Box 8730, Beijing 100080)(Shanghai Institute of Nuclear Research, the Chinese Academy of Sciences, Shanghai 201800)(Computing Center of Shanghai Branch, the Chinese Academy o | 1998 | Nuclear Science and Techniques1998，9，2： | 0 |
| 20 | 结4核可潜伏40年以上显示文摘 | 韩锟 O'Regan Martin Joyce-Brady Pulmonary Center | 2002 | 英国医学杂志中文版2002，5，2： | 0 |
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