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| 1 | A Variational Finite Element Model for Large-Eddy Simulations of Turbulent Flows显示文摘The authors introduce a new Large Eddy Simulation model in a channel,based on the projection on finite element spaces as filtering operation in its variational form,for a given triangulation{Th}h>0.The eddy viscosity is expressed in terms of the friction velocity in the boundary layer due to the wall,and is of a standard sub grid-model form outside the boundary layer.The mixing length scale is locally equal to the grid size.The computational domain is the channel without the linear sub-layer of the boundary layer.The no-slip boundary condition(or BC for short)is replaced by a Navier(BC)at the computational wall.Considering the steady state case,the authors show that the variational finite element model they have introduced,has a solution(vh,ph)h>0that converges to a solution of the steady state Navier-Stokes equation with Navier BC. | Toma's Chac'on REBOLLO Roger LEWANDOWSKI | 2013 | Chinese Annals of Mathematics,Series B2013，34，5： | 2 |
| 2 | Phosphate starvation induces a determinate developmentalprogram in the roots of Arabidopsis thaliana显示文摘 | Sánchez-Calderón L López-Bucio J Chacón-López A | 2005 | Plant CellPhysiol2005，46，1： | 1 |
| 3 | Evolution of lip-id profile,liver function,and pattern of plasma fatty ac-ids according to the type of lipid emulsion administered inparenteral nutrition in the early postoperative period afterdigestive surgery显示文摘 | Puiggròs C Sánchez J Chacón P | 2009 | JPEN J Parenter Enteral Nutr2009，33，5： | 1 |
| 4 | Effect of compound K, a metabolite of ginseng saponin, combined with 7 -ray radiation in human lung cancer cells in vitro and in vivo显示文摘 | Chac S Kang K A Chang W Y | 2009 | J Agric Food Chem2009，57，13： | 1 |
| 5 | Differential pattern of cytokine expression by macrophages infected in vitro with different Mycobacterium tuberculosis genotypes显示文摘 | Chacón-Salinas R Serafin-López J Ramos-Payán R Méndez-Aragón P Hernández-Pando R Van Soolingen D Flores-Romo L Estrada-Parra S Estrada-Garcia I | 2005 | Clin Exp Immunol2005，140，3： | 1 |
| 6 | A study on optical device alignment system using ultra precision multi-axis stage显示文摘 | JEONG S H KIMB G H CHAC K R | 2007 | J Mate Prec Techno2007，65，： | 1 |
| 7 | Origin and patterns of distribution of trace dements in streets dust: Unleaded petrol and urban lead 显示文摘 | de Miguel E Llamas J F Chacón E Berg T Larssen S Rφyset O Vadset M | 1997 | Atmos Environ1997，31，17： | 1 |
| 8 | A study on optical device alignment system using ultra precision multi-axis stage 显示文摘 | Jeong S H Kimb G H Chac K R | 2007 | Journal of Materials Processing Technology2007，，65： | 1 |
| 9 | Evolution of lipid profile,liver function,and pattern of plasma fatty acids according to the type of lipid emulsion administered in parenteral nutrition in the early postoperative period after digestive surgery显示文摘 | Puiggròs C Sánchez J Chacón P | 2009 | JPEN J Parenter Enteral Nutr2009，33，5： | 1 |
| 10 | Role of double-balloon enteroscopy in malignant small bowel tumors显示文摘AIM: To assess the double-balloon enteroscopy(DBE) role in malignant small bowel tumors(MSBT).METHODS: This is a retrospective descriptive study performed in a single center. All consecutive patients who underwent a DBE with final diagnosis of a malignant neoplasm from 2004 to 2014 in our referral center were included. Patient demographic and clinical pathological characteristics were recorded and reviewed. MSBT diagnosis was achieved either by DBE directed biopsy with multiple tissue sampling, endoscopic findings or histological analysis of surgical specimen. We have analyzed double-balloon enteroscopy impact in outcome and clinical course of these patients. RESULTS: Of 627 patients, 28(4.5%)(mean age = 60 ± 17.3 years) underwent 30 procedures(25 anterograde, 5 retrograde) and were diagnosed of a malignant tumor. Patients presented with obscure gastrointestinal bleeding(n = 19, 67.9%), occlusion syndrome(n = 7, 25%) and diarrhea(n = 1, 3.6%). They were diagnosed by DBE biopsy(n = 18, 64.3%), histological analysis of surgical specimen(n = 7, 25%) and unequivocal endoscopic findings(n = 2, 7.1%). Gastrointestinal stromal tumor(n = 8, 28.6%), adenocarcinoma(n = 7, 25%), lymphoma(n = 4, 14.3%), neuroendocrine tumor(n = 4, 14.3%), metastatic(n = 3, 10.7%) and Kaposi sarcoma(n = 1, 3.6%) were identified. DBE modified outcome in 7 cases(25%), delaying or avoiding emergency surgery(n = 3), modifying surgery approach(n = 2) and indicating emergency SB partial resection instead of elective approach(n = 2).CONCLUSION: DBE may be critical in the management of MSBT providing additional information that may be decisive in the clinical course of these patients. | Enrique Pérez-Cuadrado Robles Pilar Esteban Delgado Paloma Bebia Conesa Blanca Martínez Andrés Milivoj Franulic Guggiana Eduardo Alcaraz Mateos Mariana Fernández Caballero José Luis Rodrigo Agudo Silvia Chacón Martínez Rafael Latorre Federico Soria Juan Manuel Herrerías Gutiérrez Enrique Pérez-Cuadrado Martínez | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，6： | 1 |
| 11 | Interaction of Escherichia coli O157.H7 with Leafy Green Produce显示文摘 | Xicohtencati-Cortes Juan Chacón Ethel Sánchez Salda?a Zeus Freer Enrique Girón Jorge A | 2009 | Journal of Food Protection2009，，7： | 1 |
| 12 | Charac-terization of low phosphorus insen-sitive mutants reveals a crosstalk between low phosphorus-induced determinate root development and the activation of genes involved in the adaptation of Arabidopsis to phosphorus deficiency显示文摘 | Sánchez-Calderón L López-Bucio J Chacón-López A | 2006 | Plant Physiol2006，140，： | 1 |
| 13 | Evaluation of therapeutic potentials of site-specific PEGylated glucagon-like peptide-1 isomers as a type 2 anti-diabetic treatment:lnsulinotropic activity,glucose-stabilizing capability,and proteolytic stability显示文摘 | Youn YS Chac SY Lee S | 2007 | Biochemical Pharmacology2007，73，： | 1 |
| 14 | Implementation of a virtual multicenter gastrointestinal tumor board to reduce cancer disparities in Argentina显示文摘Given the increasing complexity of cancer care,multidisciplinary tumor boards have become essential in daily clinical oncology practice.The Project Extension for Community Healthcare Outcomes(ECHO)initiative developed an innovative telementoring model using a'hub and spoke'design consisting of a team of experts(hub)that offers a full service to multiple participants(the spokes)during regularly scheduled sessions discussing patients'clinical cases.The Alexander Fleming Cancer Institute in Buenos Aires was the first hub in Latin America to implement Project ECHO for gastrointestinal tumors.In our 3-year experience,80 patients from 37 centers were evaluated within Project ECHO and a range of three to five cases were discussed in each meeting.From our perspective,the impact of this novel approach was a remarkable strategy to reduce care disparities by equalizing access to high-quality medical knowledge in a multidisciplinary environment for medical discussions.Additionally,it was shown to have a cost-effective impact directly on the patients and the local health system,since relevant costs were saved after unnecessary treatments,studies and travel expenses were avoided. | Federico Esteso Natalia Soledad Tissera Juan Manuel O'Connor Romina Luca Eduardo Huertas Fernando Sánchez Loria Ivana Pedraza Alejandro Pairola Fernando Brancato Lisandro Paganini Mariana Kucharczyk Mora Amat Maria Teresa Pombo Mariana Galli Luisina Bruno Luis Caro Andrés Rodriguez Diego Enrico Federico Waisberg Matías Chacón | 2022 | World Journal of Clinical Oncology2022，13，6： | 0 |
| 15 | Best surgical treatment for very large benign prostatic obstruction显示文摘AIM:To investigate the best surgical treatment for very large benign prostatic obstruction(BPO).METHODS:A revision of literature was conducted in Pub Med database with 167 search results.Key words for the search were benign prostatic hyperplasia,surgical treatment,large,and volume.Inclusion criteria for this study were surgical treatment of benign prostatic obstruction for prostates equal to or larger than 80 cc.Among article search results,9 completed inclusion criterion and were revised.Each surgical technique included in those articles was compared to each other.The results were observed,and conclusions derived from this are presented.There is no statistical analysis.RESULTS:Of the 5 techniques presented in the revised articles[open transvesical enucleation,holmiumlaser enucleation of the prostate(HoL EP),photoselective vaporization of the prostate using potassium titanyl phospate laser,transurethral resection with bipolar energy,and transurethral enucleation with bipolar energy],open transvesical enucleation best permits the resolution of obstructive symptoms.It presents excellent maximum flow rates,high resected tissue volume and maintenance of results over time.These characteristics explain why it has been the gold standard treatment for prostates greater than 80 cc.However,it is at the expense of greater blood loss,urethral catheter and hospital stay times.Since its initial application in1996,the transurethral enucleation of the prostate by means of a holmium laser has become a procedure that has similar surgical outcomes with fewer complications when compared to open surgery making it an interesting alternative for very large BPO.Nonetheless,no procedure has removed open surgery as the gold standard for very large BPO.CONCLUSION:Open surgery has proved to be the gold standard for very large BPO.HoL EP appears as a minimally invasive alternative with same benefits but less morbidity. | Iván D Sáez Juan F de la Llera Cristopher D Horn José F López Rodrigo A Chacón Pedro A Figueroa Bruno I Vivaldi Fernando Coz | 2014 | World Journal of Clinical Urology2014，3，3： | 0 |
| 16 | Pre-transplant treatment of large polycystic kidney显示文摘AIM: To evaluate the indications, optimal timing andoutcomes of native nephrectomy and other techniques in pretransplant treatment of autosomal dominant polycystic kidney disease(PKD).METHODS: A literature review was conducted using the Pub Med and Epistemonikos databases. Keywords for pre-transplant surgical management of polycystic kidneys were: Transplant, treatment and PKD. Keywords for pre-treatment embolization of PKD were: Embolization, transplant and polycystic kidney disease. The inclusion criterions were all articles found using this search method. The exclusion criterions were articles found to include bias and not attending pre-transplant treatment options. Fifteen articles were included in our final analysis. Ten articles were found regarding embolization of PKD of which three reviews were selected for final analysis. The reviews were divided into pre transplant and intra transplant treatment for the surgical treatment of PKD. All articles meeting inclusion criteria were thoroughly analyzed by two independent reviewers. A third independent reviewer was consulted if the reviewers did not agree upon the inclusion or exclusion of a specific article. No statistical analysis was performed.RESULTS: Studies vary regarding the technique used(open or laparoscopic), laterality(single or bilateral) and temporality of nephrectomy with respect to renal transplant(pre-transplant or simultaneous to transplant). Several groups argue in favor of simultaneous nephrectomy and kidney transplant since it avoids the deleterious effects of being anefric. Long-term results and patient satisfaction are acceptable. However, it is associated with increased operative time, transfusion rate, morbidity and length of hospital stay. Based on small sample studies, bilateral nephrectomy prior to transplant has been associated with a higher risk of morbidity and mortality. Studies on laparoscopic approach report it as a feasible and safe alternative to the open surgery approach, highlighting its lower complication rate, transfusions and shorter hospital stay. Arterial embolization of the kidney appears as an effectiveand low morbid alternative for the management of large native kidneys. The reduction in renal size allow transplant in a significant number of patients, which makes it an appealing alternative to surgery.CONCLUSION: There is limited evidence regarding best pretrasnplant treatment of large PKD but to date embolization seems an appealing alternative to augment space for renal graft allocation. | Iván D Sáez Juan F de la Llera Andrés Tapia Rodrigo A Chacón Pedro A Figueroa Bruno I Vivaldi Alfredo Domenech Christopher D Horn Fernando Coz | 2016 | World Journal of Clinical Urology2016，5，1： | 0 |
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