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| 1 | 香港华人妇女产后抑郁危险因素的前瞻性研究显示文摘目的:产后抑郁是一种常见的精神障碍,对产妇、新生儿和其它家庭成员导致广泛的伤害。产后抑郁的病因学研究大多是基于西方样本,对其中的社会文化原因也缺乏实证研究。本研究从人口学、心理社会及种族文化因素等方面探讨中国妇女产后抑郁症状学的决定因素。方法:在大学附属综合医院产前门诊连续收集登记的中国孕妇959例,从她们第一次产前检查开始评估(基线),以后分别在孕期的最后3个月、产后即刻和产后3个月时评估。调查涉及的危险因素分6个方面:人口学和社会经济背景,躯体疾病及精神疾病病史, 产前抑郁情绪,围生期应激源,人际关系,和种族文化环境。采用等级回归进行分析。因变量是产后3个月时的抑郁评分。结果:决定产后抑郁症状学的因素有:目前的生活事件,缺乏社会支持,婚姻不满意,既往有故意自伤史,以及产前存在抑郁情绪。婆媳关系不好和没有陪月在产后阶段也与抑郁评分高有关联。结论:西方研究所确立的产后抑郁危险因素大体适用于中国妇女。产褥期的社会文化特点同样对产妇情绪有影响。 | Dominic TS Lee Alexander SK Yip Sandra SM Chan Fiona FY Lee Tony YS Leung Tony KH Chung | 2005 | 中国心理卫生杂志2005，19，9： | 50 |
| 2 | Outcome analysis of management of liver trauma: A 10-year experience at a trauma center显示文摘AIM: To review the outcomes of liver trauma in patients with hepatic injuries only and in patients with associated injuries outside the liver.METHODS: Data of liver trauma patients presented to our center from January 2003 to October 2013 were reviewed. The patients were divided into two groups. Group 1 consisted of patients who had hepatic injuries only. Group 2 consisted of patients who also had associated injuries outside the liver.RESULTS: Seven(30.4%) patients in group 1 and 10(28.6%) patients in group 2 received non-operative management; the rest underwent operation. Blunt trauma occurred in 82.8%(48/58) of the patients and penetrative trauma in 17.2%(10/58). A higher injury severity score(ISS) was observed in group 2(median 45 vs 25, P < 0.0001). More patients in group 1 were hemodynamically stable(65.2% vs 37.1%, P = 0.036). Other parameters were comparable between groups. Group 1 had better 30-d survival(91.3% vs 71.4%, P = 0.045). On multivariate analysis using the logistic regression model, ISS was found to be associated with mortality(P = 0.004, hazard ratio = 1.035, 95%CI:CONCLUSION: Liver trauma patients with multiple injuries are relatively unstable on presentation. Despite a higher ISS in group 2, non-operative management was possible for selected patients. Associated injuries outside the liver usually account for morbidity and mortality. | Wong Hoi She Tan To Cheung Wing Chiu Dai Simon HY Tsang Albert CY Chan Daniel KH Tong Gilberto KK Leung Chung Mau Lo | 2016 | World Journal of Hepatology2016，8，15： | 3 |
| 3 | 心脏病及非心脏病患者降低舒张压的效果:收缩压干预试验结果分析显示文摘收缩压和舒张压低于何种阈值时心血管事件增多仍然不明确。应用收缩压干预试验(systolic blood pressure intervention trial,SPRINT)的数据,研究者评估了1519例心血管病患者和7574位非心血管病者的收缩压和舒张压与心血管事件之间的关系。 | 刘青 叶鹏 Khan NA Rabkin SW Zhao Y McAlister FA Park JE Guan M Chan S Humphries KH | 2018 | 中华高血压杂志2018，26，6： | 3 |
| 4 | Mesenteric fat thickness as an independent determinant of fatty liver显示文摘 | Liu KH Chan YL Chan JC | 2006 | Int J Obes(Lond)2006，30，5： | 1 |
| 5 | In vitro susceptibility of ten clinical isolates of SARS coronavirus to selected antiviral compounds显示文摘 | Chen F Chan KH Jiang Y | 2004 | J Clin Virol2004，31，： | 1 |
| 6 | Comparative epidemiology of pandemic and seasonal influenza A in households显示文摘 | Cowling BJ Chan KH Fang VJ | 2010 | N Engl J Med2010，362，： | 1 |
| 7 | An investigation into the use of restriction endonuclease analysis for the study of transmission of mu-tans streptococci显示文摘 | Kulkarni GV Chan KH Sandham HJ | 1989 | J Dent Res1989，68，7： | 1 |
| 8 | In vitro susceptibility of 10 clinical isolales of SARS eoronavirua to selected antiviral compounds显示文摘 | Chen F Chan KH Jiang Y | 2004 | J clin-Virol2004，31，1： | 1 |
| 9 | Adiponectin is pro-tective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity显示文摘 | CHAN KH LAM KS CHENG OY | 2012 | Plos One2012，7，12： | 1 |
| 10 | The relationship between coronary stenosis severity and compression type coronary artery movement in acute myocardial infarction显示文摘 | Chan KH Chawantanpipat C Gattorna T | 2010 | Am Heart J2010，159，4： | 1 |
| 11 | Molecular detection of a novel human influenza (H1N1) of pandemic potential by eonven- tional and real-time quantitative RT-PCR assays显示文摘 | Pooh LL Chan KH Smith GJ | 2009 | Clin Chem2009，55，8： | 1 |
| 12 | In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds显示文摘 | Chen F Chan KH Jiang Y | 2004 | J Clin Virol2004，31，1： | 1 |
| 13 | Assessing the risk of nasopharyngeal carcinoma on the basis of EBV antibody spectrum显示文摘 | Cheng WM Chan KH Chen HL etag | 2002 | Int J Cancer2002，97，4： | 1 |
| 14 | Therapeutic effects of acupuncture for neurogenie dysphagia-a randomized controlled trial 显示文摘 | Chan SL Or KH Sun WZ | 2012 | J Tradit Chin Meal2012，1532，1： | 1 |
| 15 | Acurte haemodynamic and myocardial metabolic effects of intravcnous urapidil in severe heart failure显示文摘 | Wang RYC Chow JSF Chan KH | 1984 | Eur Heart J1984，5，： | 1 |
| 16 | Central nervous system inflammatory demyelinating disorders among Hong Kong Chinese 显示文摘 | Chan KH Lee R Lee JC | 2013 | J Neuroimmunol2013，262，12： | 1 |
| 17 | Posterior reversible eneephalopathy syndrome with vasospasm in a postpartum woman after postdural puncture headache following spinal anesthesia 显示文摘 | Ho CM Chan KH | 2007 | Anesth Analg2007，105，3： | 1 |
| 18 | Long-Term Outcome and Prognostic Factors after Spontaneous Cerebellar Hemorrhage 显示文摘 | Pong V Chan KH Chong BH | 2012 | Cerebellum2012，11，1： | 1 |
| 19 | Cerebral infarcts complicating tuberculous meningitis显示文摘 | Chan KH Cheung RT Lee R | 2005 | Cerebrovasc Dis2005，19，6： | 1 |
| 20 | Facemasks and hand hygiene to prevent influenza transmission in households: a cluster randomized trial显示文摘 | Cowling B J Chan KH Fang VJ | 2009 | Ann Inter Med2009，151，7： | 1 |
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