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839篇 您的检索式：作者名="Chandra J"

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	题名	作者	年代	出处	被引量
1	Technique for rapid detection of phthalates in water and beverages显示文摘	Asif I. Zia Mohd Syaifudin Abdul Rahman Subhas Chandra Mukhopadhyay Pak-Lam Yu I.H. Al-Bahadly Chinthaka P. Gooneratne Jǘrgen Kosel Tai-Shan Liao	2013	Journal of Food Engineering2013，，2：	2
2	Mechanism of fluconazole resistance in Candida albicans biofilms:phase-specific role of efflux pumps and membrane sterols显示文摘	Mukherjee PK Chandra J Kuhn DM		0，，：	2
3	Hepatocellular carcinoma xenograft supports HCV replication:A mouse model for evaluating antivirals显示文摘AIM: To develop a hepatocellular carcinoma (HCC) xenograft model for studying hepatitis C virus (HCV) replication in a mice, and antiviral treatment.METHODS: We developed a stable S3-green fluorescence protein (GFP) cell line that replicated the GFP-tagged HCV sub-genomic RNA derived from a highly efficient JFH1 virus. S3-GFP replicon cell line was injected subcutaneously into γ-irradiated SCID mice. We showed that the S3-GFP replicon cell line formed human HCC xenografts in SCID mice. Cells were isolated from subcutaneous tumors and then serially passaged multiple times in SCID mice by culturing in growth medium supplemented with G-418. The mouse-adapted S3-GFP replicon cells were implanted subcutaneously and also into the liver of SCID mice via intrasplenic infusion to study the replication of HCV in the HCC xenografts. The tumor model was validated for antiviral testing after intraperitoneal injection of interferon-α (IFN-α). RESULTS: A highly tumorigenic S3-GFP replicon cell line was developed that formed subcutaneous tumors within 2 wk and diffuse liver metastasis within 4 wk in SCID mice. Replication of HCV in the subcutaneous and liver tumors was confirmed by cell colony assay, detection of the viral RNA by ribonuclease protection assay and real-time quantitative reverse transcription polymerase chain reaction. High-level replication of HCV sub-genomic RNA in the tumor could be visualized by GFP expression using fluorescence microscopy. IFN-α cleared HCV RNA replication in the subcutaneous tumors within 2 wk and 4 wk in the liver tumor model. CONCLUSION: A non-infectious mouse model allows us to study replication of HCV in subcutaneous and metastatic liver tumors. Clearance of HCV by IFN-α supports use of this model to test other anti-HCV drugs.	Sidhartha Hazari Henry J Hefler Partha K Chandra Bret Poat Feyza Gunduz Tara Ooms Tong Wu Luis A Balart Srikanta Dash	2011	World Journal of Gastroenterology2011，17，3：	2
4	Crystal doping aided by rapid expansion of supercritical solutions 显示文摘	Chandra V Matthew J M Thomas E N	2002	AAPS Pharm-SciTech2002，3，4：	1
5	Morphology and mechanical properties of intermetallic compounds in SnAgCu solderjoints显示文摘	Chandra Rao B S S Weng J Shen L	2010	MicroelectronEngineering2010，87，11：	1
6	A spectral simulation approach to evaluate probabilisticmeasurement precision of a reactor coolant pump torsionalvibration shaft crank monitoring system 显示文摘	TRETHEWEYM W FRIELL J C CHANDRA M J	2008	Journal ofSound and Vibration2008，310，：	1
7	Drought stress inducedchanges in lipid peroxidation and antioxidant system in genus avena显示文摘	Pandey Harish C Baig M J Chandra A	2010	The Journal of Environmental Biology2010，31，4：	1
8	Chemistry and structural evaluation of dif-ferent phospholipase A2 inhibitors in arachidonic acidpathway mediated inflammation and snake venom toxicity显示文摘	Narendra Sharath Chandra J N Ponnappa K C Sadashi-va C T	2007	Curr Top Med Chem2007，7，8：	1
9	Modeling thermal spray coating processes: a powerful tool in design and optimization 显示文摘	MOSTAGHIMI J CHANDRA S GHAFOUR AZER R	2003	Surf Coat Technol2003，16，：	1
10	显示文摘	Chandra M Xu Q J	2006	Power Sources2006，156，2：	1
11	Alcohol dehydro-genase restricts the ability of the pathogen Candida albicans toform a biofilm on catheter surfaces through an ethanol-basedmechanism显示文摘	Mukherjee PK Mohamed S Chandra J	2006	Infect Immun2006，74，7：	1
12	Uses and limitations of the XTT assay in studies of Candida growth and metabolism显示文摘	Kuhn DM Balkis M Chandra J	2003	Clin Microbiol2003，34，3：	1
13	Shape memory alloy actuation for active tuning of composite beams显示文摘	Epps J Chandra R	1997	Smart Mater Struct1997，6，：	1
14	Characterization and partial purification of Candida albicans secretory IL-12 inhibitory factor 显示文摘	WANG Ming-yue MUKHERJEE P K CHANDRA J	2008	BMC Microbiol2008，8，1：	1
15	Disruption of the ECM33 gene in Candida albicans prevents biofilm formation, engineered human oral mucosa tissue damage and gingival cell necrosis/apoptosis 显示文摘	Rouabhia M Semlali A Chandra J Mukherjee P Chmielewski W Ghannoum MA	2012	Mediators Inflamm2012，2012，39：	1
16	Ge- nome-wide analysis of the role of GlnR in Strepto- myces venezuelae provides new insights into global nitrogen regulation in actinomycetes显示文摘	Pullan ST Chandra G Bibb M J	2011	BMC Ge- nomies2011，12，1：	1
17	Diagnostic modalities for gas- tro-esophageal reflux in infantile wheezers显示文摘	Patra S Singh V Chandra J	2011	J Trop Pediatr2011，57，2：	1
18	Geriatric syndromes as predictors of one-year mortality in an outpatient practice显示文摘	Chandra A North F Hanson G J	2013	Eur Geriatr Med2013，4，1：	1
19	Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi)显示文摘	Gu J Noe A Chandra P	2010	J Clin Pharmacol2010，50，4：	1
20	Mechanical characteristics and mechanism of the triboluminescence of fluorescent molecalar crystal显示文摘	Chandra B P Zink J I	1980	Journal of Chemical Physics1980，73，12：	1

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