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		题名	作者	年代	出处	被引量
	1	Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study显示文摘AIM Toll like receptors plays a significant anti-viral role in different infections. The aim of this study was to look into the role of toll like receptor 4(TLR4) in hepatitis B virus(HBV) infection.METHODS Real time PCR was used to analyze the transcription of TLR4 signaling molecules, cell cycle regulators and HBV DNA viral load after triggering the Hep G2.2.15 cells with TLR4 specific ligand. Nuclear factor(NF)-κB translocation on TLR4 activation was analyzed using microscopic techniques. Protein and cell cycle analysis was done using Western Blot and FACS respectively.RESULTS The present study shows that TLR4 activation represses HBV infection. As a result of HBV suppression, there are several changes in host factors which include partial release in G1/S cell cycle arrest and changes in host epigenetic marks. Finally, it was observed that anti-viral action of TLR4 takes place through the NF-κB pathway.CONCLUSION The study shows that TLR4 activation in HBV infection brings about changes in hepatocyte microenvironment and can be used for developing a promising therapeutic target in future.	Dipanwita Das Neelakshi Sarkar Isha Sengupta Ananya Pal Debraj Saha Manikankana Bandopadhyay Chandrima Das Jimmy Narayan Shivram Prasad Singh Runu Chakravarty	2016	World Journal of Gastroenterology2016，22，47：	4
	2	Male germ cell apotosis:regulation and biology显示文摘	CHANDRIMA S RAKSHAMANI T DURGA PM	2010	Philos Trans R Soc Lond B Biol Sci2010，365，1546：	1
	3	Proliferative T-cell responses to human papillomavirus type 16 E5 are decreased amongst women with high-grade neoplasia显示文摘	Dilbinder K Gill Jon M Bible Chandrima Biswas		0，，：	1
	4	N-acetylcysteine prevents MAA induced male germ cell apoptosis: role of glutathione and cytochromec 显示文摘	Kondala R Chandrima S	2002	FEBS Letters2002，527，：	1
	5	Impact of India-ASEAN Free Trade Agreement:A cross-country analysis using applied general equilibrium modeling显示文摘	Chandrima Sikdar Biswajit Nag	2011	Asia-Pacific Research and Training Network on Trade Working Paper2011，，107：	1
	6	Transcriptional Regulation of the mdm20ncogene by p53 Requires TRRAP Acetyhransferase Complexes 显示文摘	Penny G Ard Chandrima Chatterjee Sudeesha Kunjibettu	2002	MOL CELL BIOL2002，22，16：	1

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