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1篇 您的检索式:作者名="Changwan Hong"
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1Novel endogenous endoplasmic reticulum transmembrane protein SURF4 suppresses cell death by negatively regulating the STING-STAT6 axis inmyeloid leukemia显示文摘Dear Editor,Myeloid differentiation was shown to be associated with reduced leukemic cell burden and leukemia-initiating cells and improved survival[1].Reactive oxygen species(ROS)are associated with leukemia and can induce endoplasmic reticulum(ER)stress.ER stress induces several mechanisms,including cell death[2].The stimulator of interferon genes(STING)is also an ER transmembrane protein and promotes anti-tumor immunity by linking innate and adaptive immunity[3].Signal transducer and activator of transcription 6(STAT6)plays a prominent role in adaptive immunity by transducing signals fromextracellular cytokines and inducing apoptosis in cancer cells[4].Jayoung Kim Hansong Lee Chae Mi Hong Ji Ho Nam Hye Ju Yeo Woo Hyun Cho Hyung-Sik Kim Changwan Hong Yun Hak Kim Dongjun Lee 2023Cancer Communications2023,43,3:0
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