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| 1 | Quantitative analysis of miroestrol and kwakhurin for standardisation of Thai miracle herb ‘Kwao Keur’ (Pueraria mirifica) and establishment of simple isolation procedure for highly estrogenic miroestrol and deoxymiroestrol显示文摘 | Satoko Shimokawa Takuya Kumamoto Tsutomu Ishikawa Miho Takashi Yoshihiro Higuchi Chaiyo Chaichantipyuth Sunee Chansakaow | 2013 | Natural Product Research (-)2013，，4： | 1 |
| 2 | Isoflavonoids from Pueraria mirifica and their estrogenic activity显示文摘 | Chansakaow S Ishikawa T Sekine K | 2000 | Planta med2000，66，6： | 1 |
| 3 | Chemical compositions and biological activities of essential oils obtained from some Apiaceous and Lamiaceous plants collected in Thailand显示文摘Objective: To determine the chemical composition, as well as the antioxidant, antityrosinase and antibacterial activities of essential oils obtained from some Apiaceous and Lamiaceous plants collected in Thailand. Methods: The essential oils of the specified spices and aromatic herbs were obtained by hydro-distillation, and their chemical constituents were analyzed by gas chromatography/mass spectrometry. Antioxidant assays were based on the scavenging effects of 2,2-Diphenyl-1-picrylhydrazyl(DPPH) and 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)(ABTS) free radicals as well as the lipid oxidation inhibition of β-carotene bleaching by linoleic acid. Tyrosinase enzyme inhibition was evaluated by the dopachrome method. Broth microdilution technique was performed for the purposes of studying microbial growth inhibition against the isolated bacterial strains. Results: The essential oils of Elsholtzia stachyodes, Coleus amboinicus(I) and Trachyspermum ammi presented a high degree of potency in DPPH, ABTS and β-carotene bleaching assays. The Trachyspermum ammi oil, which mainly contained thymol(49.04%) and p-cymene(22.06%), proved to be the most effective in terms of antibacterial activity. The major compositions of Coleus amboinicus(I) were carvacrol(51.57%), γ-terpinene(18.04%) and p-cymene(7.81%); while thymol(43.76%) and γ-terpinene(24.61%) were identified as the major components of Elsholtzia stachyodes oil, with p-cymene(6.73%) being identified as a minor constituent. Moreover, Cuminum cyminum oil containing cuminaldehyde(49.07%) and Elsholtzia communis oil composed with geranial(44.74%) and neral(35.27%) as the major components displayed a specific ability for the inhibition of the mushroom tyrosinase enzyme. Conclusions: The results indicated that these bioactive essential oils obtained from indigenous herbs are of significant interest as alternative raw materials in food, cosmetic and medicinal products. | Nawanit Thanaseelungkoon Jakaphun Julsrigival Kulwadee Phannachet Sunee Chansakaow | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，8： | 1 |
| 4 | Isoflavonoids from Pueraria mirifica and their estrogenic activity 显示文摘 | Ishikawa T Sekine K | 2000 | Planta Med2000，66，6： | 1 |
| 5 | Identification of deoxymiroestrol as the actual rejuvenating principle of ″Kwao Keur″,pueraria mirifica-The known miroestrol may be an artifact 显示文摘 | Ishikawa T Seki H | 2000 | J Nat Prod2000，63，2： | 1 |
| 6 | Effects of Solanum torvum fruit water extract on hyperlipidemia and sex hormones in high-fat fed male rats显示文摘Objective:To study the effect of water extract of Solanum torvum(S.torvum) on blood lipid and sex hormone levels in high-fat diet(HFD) fed male rats.Methods:Male Wistar rats were maintained on a standard diet or HFD for 10 weeks.During the last 4 weeks,the standard diet groups received distilled water or S.torvum(400 mg/kg) and the HFD groups received distilled water or S.torvum(100,200 and400 mg/kg).Body weight,lipid profiles,sex hormone,internal organs weight and liver histopathology were all measured.Moreover,kidney function was evaluated using blood urea nitrogen and creatinine levels,and liver function by the levels of aspartate aminotransferase and alanine aminotransferase.Results:The result showed that rats in the HFD control group had increased body weight and hyperlipidemia,but had decreased levels of both testosterone and estradiol.When receiving the S.torvum extract at a dose of 100 mg/kg,treated rats had significantly increased sex hormone levels of both types,and decreased total cholesterol levels,and at a dose of 200 mg/kg,treated rats had significantly decreased levels of triglyceride.Long term administration of the S.torvum did not produce any toxic signs in livers and kidneys.Pathological examinations of livers showed lipid accumulation in the HFD group,but the treatment of S.torvum slightly reduced lipid deposition in liver tissue.Conclusions:S.torvum extract can reverse the level of sex hormones to their normal level and reduce serum cholesterol in HFD-induced obese male rats.Furthermore,the long term oral administration of S.torvum extract is harmless. | Supaporn Wannasiri Sunee Chansakaow Seewaboon Sireeratawong | 2017 | Asian Pacific Journal of Tropical Biomedicine2017，7，5： | 1 |
| 7 | Isoflavonoids from Pueraria mirifica and their estrogenic activity 显示文摘 | Chansakaow S Ishikawa T Sekine K | 2000 | Planta Med2000，66，6： | 1 |
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