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| 1 | 中国基层医疗二型糖尿病人中阳痿的普遍性,相互关联,患者态度和寻求治疗的行为显示文摘本研究探讨在基层医疗二型糖尿病人中,阳痿的普遍性、相互关联、患者态度和寻求治疗的行为。我们将一份结构性匿名自填问卷发放到十所普通科门诊诊所进行横断性调查。在603位参与者(91%回应率)中,以国际勃起功能指数(iief)作定义之阳痿的普遍性为79.1%。多数参与者患轻度阳痿(28.9%),随后为轻至中度阳痿(27.9%)、中度阳痿(13.4%)及严重阳痿(9%)。接近55%的阳痿患者并不自觉患有此症。少于10%的患者曾寻求医生治疗,76.1%的参与者表示若被确诊为阳痿,会期望得到医生治理。他们认为最重要的医生治理是临床评估(41.7%),其次是治理潜在因素(37.8%)、转介专科医生(27.5%)、教育(23.9%)、处方磷酸二酯酶5型抑制剂(16.9%),及转介辅导服务(6.7%)。与诊断阳痿最密切关联的因素是自觉患有阳痿(OR=90.49(20.00—409.48,P〈0.001))、以及较年长的组别(OR=1.043(1.011-1.076,P=0.008))。总体而言,阳痿在二型糖尿病人中非常普遍。其中大部分病人如患上阳痿都希望得到医生救治,但只有少数会真正提出此要求。建议医护人员使用结构性问卷筛选二型糖尿病人中的阳痿患者,有助于找出未被诊断的阳痿个案。 | Wai Hon Lo Sau Nga Fu Carlos King Ho Wong Ee San Chen | 2014 | Asian Journal of Andrology2014，16，5： | 8 |
| 2 | A major pathway for carbon and nitrogen losses-Gas emissions during storage of solid pig manure in China显示文摘This study investigated the carbon(C) and nitrogen(N) gas emissions(N_2O,NH_3,CO_2 and CH_4) from solid pig manure management in China.Gas emissions were quantified from static piles over 60 days during summer in China's Yangtze River Basin,using Drager-Tube and static chamber-gas chromatography techniques.High emissions of NH_3 and N_2 O were observed at the early stage of storage,but high emission of CH_4 occured later during storage.Overall,62% of the total C in the original pile was lost; CO_2 and CH_4 emissions accounted for 57 and 0.2% of C lost respectively.Over the same time,41% of the total N in the original pile was lost; NH_3 and N_2 O emissions accounted for 15 and 0.3% of N lost respectively.The volatilization of NH_3 during storage in summer was 4.56 g NH_3 per kg dry weight.The total greenhouse gas(GHG) emissions during storage accounted for 67.93 g CO_2 equivalent per kg dry weight; N_2 O and CH_4 contributed to 46 and 55% of total GHG emissions respectively.Given China's major role in pig production,further attention should given to pig manure management to mitigate its contribution to atmospheric pollution. | SHAN Nan LI Hu LI Jian-zheng Ee Ling Ng MA Yan WANG Li-gang CHEN Qing | 2019 | Journal of Integrative Agriculture2019，18，1： | 3 |
| 3 | Protein and RNA expression of acid-sensing ion channels 2 and 3 in myocardial ischemia rats induced by isoproterenol显示文摘OBJECTIVE:To investigate the impact of electro-acupuncture at the Neiguan(PC 6) acupoint on protein and RNA expression of acid-sensing ion channel 2(ASIC2) and ASIC3 in myocardial ischemia rats.METHODS:Fifty male Sprague-Dawley rats were used,weighing(230 ± 50) g.The rats were randomized into a normal group A,model group B,Neiguan(PC 6) group C,Lieque(LU 7) group D,and A-shi points group E.There were 10 rats in each group.Rats were continuously administered 85 mg/kg intravenous isoproterenol daily to establish the model.Successfully modeled rats in groups C,D,and E were given electro-acupuncture treatment.Each group of rats was sacrificed with chloral hydrate(1 mL/100 g) intraperitoneal injection.The left ventricular myocardium was extracted and placed at- 70 ℃ until use.Western blot analysis and real-time PCR were performed to assay protein and RNA expressions of ASIC2 and ASIC3,respectively.Fold changes in RNA expression were quantified with the 2~^(-△△Ct) method.Blood samples were drawn from the aorta abdominalis and tested for creatine kinase-MB(CK-MB) and lactate dehydrogenase(LDH) levels using enzyme-linked immunosorbent assay.RESULTS:Myocardial ischemia rats given electro-acupuncture at the Neiguan(PC 6) acupoint had significantly lower protein and RNA expression of ASIC2 and ASIC3,and CK-MB and LDH levels,compared with model rats(P < 0.01).CONCLUSION:Electro-acupuncture at the Neiguan(PC 6) acupoint can not only decrease the protein and RNA expression of ASIC2 and ASIC3,but also inhibit the opening of ASICs and reduce the cardiomyocyte damage in myocardial ischemia rats. | Wang Shudong Zhang Lide Dong Baoqiang Zhang Wenshun Ho Chin Ee Guo Na Chen Yiguo | 2015 | Journal of Traditional Chinese Medicine2015，35，2： | 2 |
| 4 | Restoration of tight junc- tion structure and barrier function by down - regulation of the mitogen - activated protein kinase pathway in ras - transformed Madin -Darby canine kidney cells显示文摘 | Chen Y Lu Q Schneeberger EE | 2000 | Mol Biol Cell2000，11，3： | 1 |
| 5 | Feasibility study on bioreactor strategies for enhanced photohydrogen pro- duetion from RhodopseudomomL: palustris WP3-5 using optical-fiber-assisted illumination systems显示文摘 | CHEN CY I EE CM CHANG JS | 2006 | Interna- tional Journal of Hydrogen Energy2006，31，15： | 1 |
| 6 | The size of blood-brain barrier opening induced by focused ultrasound is dictated by the acoustic pressure显示文摘 | Chen H Konofagou EE | 2014 | J Cereb Blood Flow Metab2014，34，7： | 1 |
| 7 | Cerebral amyloid angiopathy in East and West显示文摘 | Chen YW Lee MJ Smith EE | 2010 | Int J Stroke2010，5，5： | 1 |
| 8 | Evaluation of renal function of angiomyolipoma patients after selective transcatheter arterial embolization显示文摘 | l ee S Y Hsu H H Chen Y C | | Am J Med Sci0，337，2： | 1 |
| 9 | Ischemia-reperfusion impairs blood-brain barrier function and alters tight junction protein expression in the ovine fetus显示文摘 | Chen X Threlkeld SW Cumminqs EE | 2012 | Neuroscience2012，226，： | 1 |
| 10 | Dopamine from the brain promotes spinal motor neuron generation during de-velopment and adult regeneration显示文摘 | Reimer MM Norris A Ohnmacht J Patani R Zhong Z Dias TB Kuscha V Scott AL Chen YC Rozov S Frazer SL Wyatt C Higashijima S Pat-ton EE Panula P Chandran S Becker T Becker CG | | 0，，： | 1 |
| 11 | Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing 显示文摘 | Chen L Tredget EE Wu PY | 2008 | PLOS ONE2008，3，4： | 1 |
| 12 | Copper diffusion in Ti-Si-N kyers formed by inductively coupled plasma implantation显示文摘 | Ee Y C Chen Z | 2006 | Appl Surf Sci2006，253，： | 1 |
| 13 | Paraerine factors of mesenchymal stem cells recruitmacrophages and endotheli- al lineage cells and enhanee wound healing 显示文摘 | Chen L Tredget EE Wu PY | 2008 | PLoS ONE2008，3，： | 1 |
| 14 | Demographic risk factors, media- tors, and moderators in youths' diabetes metabolic control 显示文摘 | Holmes CS Swift EE Chen R | 2006 | Ann Behav Med2006，32，1： | 1 |
| 15 | Direct aperture optimization-based intensity-modulated radiotherapy for whole breast irradiation显示文摘 | Ahunbay EE Chen GP Thatcher S | 2007 | Int J Radiat Oncol Biol Phys2007，67，4： | 1 |
| 16 | Multi-criteria fuzzy optimization for lo- cating warehouses and distribution centers in a supply chain network显示文摘 | Chen C L Yuan T W L ee W C | 2007 | Journal of the Chinese Institute of Chemical Engineers2007，，38： | 1 |
| 17 | Microstructure study of PANpitch-based carbon-carbon composite显示文摘 | L EE KJ CHEN Z Y | 2003 | Materials Chemistry and Physics2003，82，： | 1 |
| 18 | The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm显示文摘 | Morrisey EE Musco S Chen MY | 2000 | J Biol Chem2000，275，19： | 1 |
| 19 | Electroless copper seed layer deposition on tantalum nitride barrier film显示文摘 | Chong S P Ee Y C Chen Z | 2005 | Surface and Coatings Tech2005，198，13： | 1 |
| 20 | Effect of processing parameters on electroless Cu seed layer properties显示文摘 | Ee Y C Chen Z Chan L | 2004 | Thin Solid Films2004，，： | 1 |
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