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| 1 | Dental caries and first permanent molar pit and fissure morphology in 7-to 8-year-old children in Wuhan,China显示文摘To obtain the caries experience and,plaque accumulation severity and pit and fissure morphology in first permanent molars in 7-8 children in Wuhan,as a reasonable prediction of caries risk and preventive attention in the future,a convenient sample of five primary schools in the vicinity of the Wuhan University School and Hospital of Stomatology was drawn.Two calibrated examiners orally examined all present grade 2 children in the classroom,using standard caries plaque and tooth morphology criteria.Dental caries was scored at enamel(D 2) and dentine(D 3) for tooth and surface level.Independent variables were age,gender and school.Data analysis used analysis of variance and t-test.The sample comprised 1 043 7-and 8-year-olds.The prevalence of dental caries in permanent dentition was 8.7% and in primary dentition,68.7%.Mean Decayed,Missing,Filled Teeth/S(DMFT/S) scores were 0.11 and 0.14,respectively.Mean dmft/s scores were 2.8 and 5.0.The d-component constituted 75% of the d 3 mft index,while enamel carious lesions constituted 36% of the total number of carious lesions(d 2,3-component).Prevalence of medium and deep pits and fissures was 84.6%.Prevalence of medium and severe plaque accumulation was 67.4%.Prevalence of dental caries in the deciduous and permanent dentitions of 7-to 8-year-old children was high.Deep pits and fissures in high caries risk children should be sealed. | Jin-Dong Wang Xi Chen Jo Frencken Min-Quan Du Zhi Chen | 2012 | International Journal of Oral Science2012，4，3： | 13 |
| 2 | LAMOST Experiment for Galactic Understanding and Exploration (LEGUE)——The survey's science plan显示文摘We describe the current plans for a spectroscopic survey of millions of stars in the Milky Way galaxy using the Guo Shou Jing Telescope (GSJT, formerly called the Large sky Area Multi-Object fiber Spectroscopic Telescope - LAMOST). The survey will obtain spectra for 2.5 million stars brighter than r < 19 during dark/grey time, and 5 million stars brighter than r < 17 or J < 16 on nights that are moonlit or have low transparency. The survey will begin in the fall of 2012, and will run for at least four years. The telescope's design constrains the optimal declination range for observations to 10 < δ < 50 , and site conditions lead to an emphasis on stars in the direction of the Galactic anticenter. The survey is divided into three parts with different target selection strategies: disk, anticenter, and spheroid. The resulting dataset will be used to study the merger history of the Milky Way, the substructure and evolution of the disks, the nature of the first generation of stars through identification of the lowest metallicity stars, and star formation through study of open clusters and OB associations. Detailed design of the LAMOST Experiment for Galactic Understanding and Exploration (LEGUE) survey will be completed in summer 2012, after a review of the results of the pilot survey. | Li-Cai Deng Heidi Jo Newberg Chao Liu Jeffrey L. Carlin Timothy C. Beers Li Chen Hsu-Tai Lee Carl J. Grillmair Puragra Guhathakurta] Zhan-Wen Han Jin-Liang Hou Sebastien Lepine Jing Li Xiao-Wei Liu Kai-Ke Pan J. A. Sellwood Bo Wang Hong-Chi Wang Fan Yang Brian Yanny Hao-Tong Zhang Yue-Yang Zhang Zheng Zheng Zi Zhu | 2012 | Research in Astronomy and Astrophysics2012，12，7： | 10 |
| 3 | MC carbide formation in directionally solidified MAR-M247LC superalloy显示文摘 | CHEN J LEE J H JO C Y CHOE S J LEE Y T | 1998 | Materials Science and Engineering A1998，247，： | 1 |
| 4 | Intraperitoneal injection of magnetic Fe3O4-nanoparticle induces hepatic and renal tissue injury via oxidative stress in mice显示文摘 | Ma P Luo Q Chen JO | 2012 | Int J of Nanomed2012，7，： | 1 |
| 5 | Amended description of the genes for synthesis of actinomyces naeslundii T14V type 1 timbriae and associated adhesin 显示文摘 | Chen P Cisar JO Hess S | 2007 | Infect Immun2007，75，8： | 1 |
| 6 | Hippophae rhamnoides L.leaves extract enhances cell proliferation and neuroblast differentiation through upregulation of intrinsic factors in the dentate gyrus of the aged gerbil显示文摘 | Ji Hyeon Ahn Bai Hui Chen Joon Ha Park In Hye Kim Jeong-Hwi Cho Jae-Chul Lee Bing Chun Yan Jung Hoon Choi In Koo Hwang Ju-Hee Park Sang-No Han Yun Lyul Lee Myong Jo Kim Moo-Ho Won | 2014 | Chinese Medical Journal2014，，23： | 1 |
| 7 | A secure and efficient SIP authentication scheme for converged VoIP networks显示文摘 | Eun-Jun Yoon Kee-Young Yoo Cheonshik Kim You-Sik Hong Minho Jo Hsiao-Hwa Chen | 2010 | Computer Communications2010，，14： | 1 |
| 8 | Epicardial induction of fetal cardiomyo- cyte proliferation via a retinoic acid-inducible trophic factor 显示文摘 | Chen TH Chang TC Kang JO | 2002 | Dev Biol2002，250，： | 1 |
| 9 | Potassium-modified Mg(NH2)2/2Li H system for hydrogen storage显示文摘 | Wang J H Liu T Wu G T Li W Liu Y F Moysés Araújo C Scheicher R H Blomqvist A Ahuja R Xiong Z T Yang P Gao M X Pan H G Chen P | 2009 | Angewandte Chemie International Edition2009，48，： | 1 |
| 10 | Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex 显示文摘 | Ivaniutsin U Chen Y Mason JO | 2009 | NeuralDev2009，4，1： | 1 |
| 11 | Regulation of TREM ex- pression in hepatic macrophages and endothelial cells during acute en- dotoxemia显示文摘 | Chen LC Laskin JO Gordon MK LaskJn DL | 2008 | Fxp Mol Pathol2008，84，2： | 1 |
| 12 | VEGF-induced vascular perme- ability is mediated by FAK 显示文摘 | Chen XL Nam JO Jean C | 2012 | Dev Cell2012，22，1： | 1 |
| 13 | Lumbar hernia:clinical analysis of 11 cases显示文摘 | Zhou X Nve JO Chen G | 2004 | Hernia2004，8，3： | 1 |
| 14 | The TGF-beta pseudoreceptor geoe Bambi is dispensable for mouse embryonic development and postnatal survival显示文摘 | Chen J Bush JO Ovitt CE | 2007 | Genesis2007，45，8： | 1 |
| 15 | Effect of KIOM-79 on Diabetes-Induced Myocardial Fibrosis in Zucker Diabetic Fatty Rats显示文摘 | Junghyun Kim Eunjin Sohn Chan-Sik Kim Yun Mi Lee Kyuhyung Jo Jin Sook Kim Keji Chen | 2013 | Evidence-Based Complementary and Alternative Medicine2013，，： | 1 |
| 16 | Human resources for health: overcoming the crisis显示文摘 | Lincoln Chen Timothy Evans Sudhir Anand Jo Ivey Boufford Hilary Brown Mushtaque Chowdhury Marcos Cueto Lola Dare Gilles Dussault Gijs Elzinga Elizabeth Fee Demissie Habte Piya Hanvoravongchai Marian Jacobs Christoph Kurowski Sarah Michael Ariel Pablos-Men | 2004 | The Lancet . 2004 (9449)2004，，： | 1 |
| 17 | A 3D finite elementmodel of anterior vaginal wall support to evaluatemechanisms underlying cystocele formation显示文摘 | Chen L Ashton-Miller JA DeLancey JO | 2009 | J Biomech2009，42，10： | 1 |
| 18 | m6A-TSHub:Unveiling the Context-specific m^(6)A Methylation and m^(6)A-affecting Mutations in 23 Human Tissues显示文摘As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs(lncRNAs),N6-methyladenosine(m^(6)A)RNA methylation has been shown to participate in essential biological processes.Recent studies have revealed the distinct patterns of m^(6)A methylome across human tissues,and a major challenge remains in elucidating the tissue-specific presence and circuitry of m^(6)A methylation.We present here a comprehensive online platform,m^(6)A-TSHub,for unveiling the context-specific m^(6)A methylation and genetic mutations that potentially regulate m^(6)A epigenetic mark.m^(6)A-TSHub consists of four core components,including(1)m^(6)A-TSDB,a comprehensive database of 184,554 functionally annotated m^(6)A sites derived from 23 human tissues and 499,369 m^(6)A sites from 25 tumor conditions,respectively;(2)m^(6)A-TSFinder,a web server for high-accuracy prediction of m^(6)A methylation sites within a specific tissue from RNA sequences,which was constructed using multi-instance deep neural networks with gated attention;(3)m^(6)ATSVar,a web server for assessing the impact of genetic variants on tissue-specific m^(6)A RNA modifications;and(4)m^(6)A-CAVar,a database of 587,983 The Cancer Genome Atlas(TCGA)cancer mutations(derived from 27 cancer types)that were predicted to affect m^(6)A modifications in the primary tissue of cancers.The database should make a useful resource for studying the m^(6)A methylome and the genetic factors of epitranscriptome disturbance in a specific tissue(or cancer type).m^(6)A-TSHub is accessible at www.xjtlu.edu.cn/biologicalsciences/m^(6)ats. | Bowen Song Daiyun Huang Yuxin Zhang Zhen Wei Jionglong Su João Pedro de Magalhães Daniel J.Rigden Jia Meng Kunqi Chen | 2023 | Genomics, Proteomics & Bioinformatics2023，21，4： | 1 |
| 19 | mTORC1 signa- ling and regulation of pancreatic I~-eell mass显示文摘 | Blandino-Rosano M Chen AY Scheys JO | 2012 | Cell Cycle2012，11，10： | 1 |
| 20 | Interdigitated hydrogen bonds:electrophile activation for covalent capture and fluorescence turnon detection of cyanide显示文摘 | JO J OLASZ A CHEN C-H | 2013 | J Am Chem Soc2013，135，9： | 1 |
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