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7篇 您的检索式:作者名="Chi AH"
    题名 作者 年代 出处 被引量
1Signaling networks in immunometabolism显示文摘Adaptive immunity is essential for pathogen and tumor eradication,but may also trigger uncontrolled or pathological inflammation.T cell receptor,co-stimulatory and cytokine signals coordinately dictate specific signaling networks that trigger the activation and functional programming of T cells.In addition,cellular metabolism promotes T cell responses and is dynamically regulated through the interplay of serine/threonine kinases,immunological cues and nutrient signaling networks.In this review,we summarize the upstream regulators and signaling effectors of key serine/threonine kinase-mediated signaling networks,including PI3K-AGC kinases,mTOR and LKB1-AMPK pathways that regulate metabolism,especially in T cells.We also provide our perspectives about the pending questions and clinical applicability of immunometabolic signaling.Understanding the regulators and effectors of immunometabolic signaling networks may uncover therapeutic targets to modulate metabolic programming and T cell responses in human disease.Jordy Saravia Jana L.Raynor Nicole M.Chapman Seon Ah Lim Hongbo Chi 2020Cell Research2020,30,4:9
2Intelligent drug-de-livery devices based on micro- and nano-technologies显示文摘Chi AH Clayton K Burrow TJ 2013Ther Deliv2013,4,:1
3The reaction of binucleo- philic reagents containing 1,4 - nucleophilic centers with perfluoro - 2 - methylpent - 2 - ene and perfluoro - 5 - azanon - 4 -ene 显示文摘Ki - Whan Chi Hyun - Ah Kim 2001Journal of Fluorine Chemistry2001,110,:1
4Living Alone and Depressionin Chinese Older Adults显示文摘CHOU K L HO AH CHI I 2006Aging Ment Health2006,,6:1
5Intelligent drug-de-livery devices based on micro- and nano-technologies显示文摘Chi AH Clayton K Burrow TJ 2013Ther Deliv2013,4,:1
6Living alone and depression in Chinese older adults显示文摘Chou KL Ho AH Chi I 2006Aging Ment Health2006,10,6:1
7Lipase-catalyzed production of phytosteryl esters and their crystallization behavior in corn oil 显示文摘Phuong Lan Vu Jung Ah Shin Chi Hwan Lim 2004Food Research International2004,37,2:1
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