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| 1 | 晶体材料织构定量分析[J]显示文摘 | 毛为民 ChinJ | | Materials Science Technol0，，： | 1 |
| 2 | Hypoxia targeted gene therapy to increase the efficacy of tirapazamine as an adjuvant to radiotherapy: Reversing tumor radioresistance and effecting cure显示文摘 | Cowen RL Williams KJ Chinje EC | 2004 | Cancer Res2004，64，4： | 1 |
| 3 | 17 beta-Oestradiol treatment modulates nitric oxide synthase activity in MDA231 tumour with impli cations on growth and radiation response显示文摘 | Chinje EC Williams KJ Telfer BA | 2002 | J Cancer(Br)2002，86，1： | 1 |
| 4 | Effects of recombinant human intedeukin - 13 on rabbit articular chondrocytes stilnulation of prostanoid release and inhibition of cell growth 显示文摘 | ChinJE Lin Y | 1988 | Arthritis and Rheum1988，31，10： | 1 |
| 5 | Hypoxia targeted gene therapy to increase the efficacy of tirapazamine as an adjuvant to radiotherapy: reversing tumor radioresistance and effecting cure显示文摘 | COWEN RL WILLIAMS KJ CHINJE EC | 2004 | Cancer Res2004，64，4： | 1 |
| 6 | 一氧化氮对肿瘤细胞辐射敏感性的影响研究显示文摘调节肿瘤细胞中一氧化氮(Nitrogenmonoxide,NO)的合成量,观察NO对细胞辐射敏感性的影响。结果显示乏氧和L-甲基盐酸精氨酸(L-NG-Monomethylargininehydrochloride,L-NMMA)作用均可显著抑制NO的合成,但对一氧化氮合酶(Induciblenitrogenmonoxidesynthase,iNOS)活性无显著影响;NO可以增强肿瘤细胞对射线的敏感性也增强,但两者变化并非线性相关;乏氧和L-NMMA作用抑制肿瘤细胞中NO的合成,会降低细胞对射线的敏感性;同母本细胞相比,基因转染建立NO含量较高的肿瘤细胞,氧增比(OxygenEnhancementRatio,ORE)下降,提示NO参与射线引起的细胞损伤。 | 孔肇路 金一尊 Chinje E C Stratford I J | 2006 | 辐射研究与辐射工艺学报2006，24，3： | 1 |
| 7 | Internalduplicationandhomologywithbacterialtransportproteinsinthemdra(p-Glycoprotein)genefrommultidrug-resistanthumancells显示文摘 | ChenCJ ChinJE UedaK etal | 1996 | Cell1996，47，3： | 1 |
| 8 | The impact of intracellular generation of nitric oxide on the radiation response of human tumor cells显示文摘 | Singh S Cowen R L Chinje E C | 2009 | Radiat Res2009，171，5： | 1 |
| 9 | 17β-oestradiol treatment modulates nitric oxide synthase activity in MDA231tumour with implications on growth and radiation response显示文摘 | Chinje EC Williams KJ Telfer BA | 2002 | Br J Cancer2002，86，1： | 1 |
| 10 | Non-nuclear localized human NOSⅡ enhanced the bio-activation and toxicity of Tirapazamine (SR4233) in vitro显示文摘 | Chinje EC Cowen RL Feng J | 2003 | Mol Pharmacol2003，63，6： | 1 |
| 11 | Induction of the cyp4a subfamily by perfluorodecanoic acid: The rat and the guinea pig as suscept~le and non - suscepti- ble species显示文摘 | Chinje E Kentish P Jarnot B | 1994 | Toxicology Letters1994，71，1： | 1 |
| 12 | Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase显示文摘 | Philip Reigan Abdul Gbaj Edwin Chinje | 2004 | Bioorganic & Medicinal Chemistry Letters2004，14，： | 1 |
| 13 | Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells 显示文摘 | Roninson lB ChinJE Choi KG | 1986 | Proc Natl Acad Sci USA1986，83，12： | 1 |
| 14 | 17β-oestradiol treatment modulates nitric oxide synthase activity in MDA231 tumour with implications on growth and radiation response显示文摘 | Chinje E C Williams K J Teller B A | 2002 | Br J Cancer2002，86，1： | 1 |
| 15 | Non-nuclear localized human NOSII enhanced the bio-activation and toxicity of Tirapazamine (SR4233) in vitro显示文摘 | Chinje E C Cowen E L Feng J | 2003 | Mol Pharmacol2003，63，： | 1 |
| 16 | On fuzzy B-algebras显示文摘 | Young B J Eun H R ChinJ | 2002 | Czechoslovak Mathematical Journal2002，52，2： | 1 |
| 17 | 一氧化氮合成酶对AQ_4N放射增敏作用的影响研究显示文摘评价1,4-二-[[2-(二甲氨基-N-氧化物)乙醇]氨基]5,8-双羟基氧化蒽-9,10-二酮((1,4-bis-{[2-(dimethylamino-N-oxide)ethyl]amino}-5,8-dihydroxyanthracene-9,10dione),AQ4N)辐射增敏效果和乏氧选择性,分析一氧化氮合成酶(Induciblenitrogenmonoxidesynthase,iNOS)对AQ4N代谢活化的影响和作用特点。结果显示AQ4N是一种低毒性的化合物,仅在乏氧条件显示较弱的细胞毒性,可以引起肿瘤细胞凋亡。AQ4N对肿瘤细胞尤其是乏氧肿瘤细胞具有良好的辐射增敏作用。同亲本细胞相比,iNOS基因转染的细胞克隆,仅在乏氧条件下显示出对AQ4N化学敏感性的增强和细胞的G2/M期阻滞。提示iNOS仅在乏氧条件下参与AQ4N的代谢活化过程。 | 孔肇路 金一尊 Chinje E C Stratford I J | 2006 | 辐射研究与辐射工艺学报2006，24，3： | 0 |
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