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60篇 您的检索式:作者名="Choiniere"
    题名 作者 年代 出处 被引量
1Exposure to inorganic arsenic can lead to gut microbe perturbations and hepatocellular carcinoma显示文摘Arsenic is a carcinogenic environmental factor found in food and drinking water around the world.The mechanisms in which arsenic alters homeostasis are not fully understood.Over the past few decades,light has been shed on varying mechanisms in which arsenic induces cancer.Such mechanisms include gut microbe perturbations,genotoxic effects,and epigenetic modification.Gut microbe perturbations have been shown to increase the level of pathogen-associated molecular patterns such as lipopolysaccharide(LPS) leading to uncontained inflammation.Increase in inflammation is the major factor in cirrhosis leading to hepatocellular carcinoma.Alterations in gut permeability and metabolites have also been observed as a fallout of arsenic induced gut microbe modification.The guts proximity and interaction through portal flow make the liver susceptible to gut perturbations and ensuing inflammatory responses.Genotoxic and epigenetic dysregulation induced by arsenic and its toxic metabolites present a more direct mechanism that works synergistically with gut microbe perturbations to induce the incidence of cancers.These pathways combined could be some of the main causes of arsenic-induced carcinogenesis.Jonathan Choiniere Li Wang 2016Acta Pharmaceutica Sinica B2016,6,5:6
2Nursing Home Staffing Standards and Staffing Levels in Six Countries 显示文摘Charlene Harrington Jacqueline Choiniere Monika Gold-mann 2012Journal of Nursing Scholarship2012,44,1:1
3Patient - controlled seda-tion using propofol for dressing changes in bum patients :a dose -finding study显示文摘Coimbra C Choiniere M Hemmerling TM 2003Anesth Analg2003,97,3:1
4Voluntary hyperventilation before a rapid-sequence induction of anesthesia does not decrease postintubation PaCO2显示文摘CHOINIERE A GIRARD F BOUDREAULT D 2001Anesth Analg2001,93,5:1
5Patient-controlled analgesia: a double-blind study in burn patients显示文摘Choiniere M Grenier R Paquette C 1992Anaesthesia1992,47,6:1
6Muscle strength in individuals with healed burns 显示文摘St-Pierre DM Choiniere M Forget R 1998Arch Phys Med Rehabil1998,79,:1
7cis-Acting elements within the Candida albicans ERG11promoter mediate the azole response through transcriptionfactor Upc2p显示文摘OLIVER BG SONG JL CHOINIERE JH 2007Eukaryot Cell2007,6,12:1
8Effect of carbon source oncompost nitrogen and carbon losses显示文摘Barrington S Choiniere D Tfigui M 2002Bioresource Technology2002,83,3:1
9Effect of carbon source on compost nitrogen and carbon losses 显示文摘Barrington S Choiniere D Trigui M 2002Bioresource Technology2002,83,3:1
10Reducing ambient temperature in farrowing houses with a new controlled-environment system显示文摘C Farmer S Robert Y Choiniere 1998Canada Journal of Animal Science1998,,:1
11Visual analogue thermometer: a valid and useful instrument for measuring pain in burned patients 显示文摘Choiniere M Auger FA Latarjet J 1994Bums : journal of the International Society for Bum Injuries1994,20,3:1
12Visual analogue thermometer:a valid and useful instrument for measuring pain in burned patients显示文摘Choiniere M Auger FA Latarjet J 0,,:1
13Effect of Carbon Source on Compost Nitrogen and Carbon Losses 显示文摘Barrington S Choiniere D Trigui M 2002Bioresource Technology2002,83,3:1
14Ultra-fast-track anesthesia in off-pump coronary artery bypass grafting:a prospective audit comparing opioid-based anesthesia vs thoracic epidural-based anesthesia显示文摘Hemmerling TM Prieto L Choiniere JL 2004Can J Anaesth2004,51,2:1
15Pain in the emergency department: results of the pain and emergency medicine initiative (PEMI) Multicenter Study 显示文摘Todd KH Ducharme J Choiniere M 2007J Pain2007,23,2:1
16Ultra-fast-track amesthesia in off-pump coronary artery bypass graftin: a prospective audit comparing opioid-based anesthesia vs thoracic epidural-based anesthesia显示文摘Hemmerling TM Prieto I Choiniere JL 2004Can J Anaesth2004,51,2:1
17Comparisons between patients and nurses assessments of pain and medication efficacy in severe burn injuries显示文摘Choiniere M Meizack R Girard N 1990Pain1990,40,:1
18The effects of hospital noise显示文摘Choiniere DB 2010Nurs Adm Q2010,34,4:1
19Visual analogue thermometer: a valid and useful instrument for measuring pain in burned patients显示文摘CHOINIERE M AUGER FA LATARJET J 1994Burns1994,20,:1
20Effect of carbon source oncompost nitrogen and carbon losses显示文摘Barrington S Choiniere D Trigui M 2002Bioresource Technology2002,83,:1
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