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| 1 | Relationship between sonographically measured median nerve cross-sectional area and presence of peripheral neuropathy in diabetic subjects显示文摘BACKGROUND Neuropathy is a common complication of diabetes mellitus resulting from direct damage by hyperglycemia to the nerves and/or ischemia by microvascular injury to the endoneurial vessels which supply the nerves. Median nerve is one of the peripheral nerves commonly affected in diabetic neuropathy. The median nerve size has been studied in non-Nigerian diabetic populations. In attempt to contribute to existing literature, a study in a Nigerian population is needed.AIM To evaluate the cross-sectional area(CSA) of the median nerve using B-mode ultrasonography(USS) and the presence of peripheral neuropathy(PN) in a cohort of adult diabetic Nigerians.METHODS Demographic and anthropometric data of 85 adult diabetes mellitus(DM) and 85 age-and sex-matched apparently healthy control(HC) subjects were taken. A complete physical examination was performed on all study subjects to determine the presence of PN and modified Michigan Neuropathy Screening Instrument(MNSI) was used to grade its severity. Venous blood was taken from the study subjects for fasting lipid profile(FLP), fasting blood glucose(FBG) and glycated haemoglobin(HbA1 c) while their MN CSA was evaluated at a point 5 cm proximal to(5 cmCATL) and at the carpal tunnel(CATL) by high-resolution Bmode USS. Data was analysed using SPSS version 22.RESULTS The mean MN CSA was significantly thicker in DM subjects compared to the HC at 5 cmCATL(P < 0.01) and at the CATL(P < 0.01) on both sides. The presence of diabetic peripheral neuropathy(DPN) further increased the MN CSA at the CATL(P < 0.05) but not at 5 cmCATL(P > 0.05). However, the severity of DPN had no additional effect on MN CSA 5 cm proximal to and at the CATL. There was no significant association between MN CSA and duration of DM and glycemic control.CONCLUSION Thickening of the MN CSA at 5 cmCATL and CATL is seen in DM. Presence of DPN is associated with worse thickening of the MN CSA at the CATL but not at5 cmCATL. Severity of DPN, duration of DM, and glycemic control had no additional effect on the MN CSA. | Fredrick ANDrew Attah Christianah Mopelola Asaleye Adeleye Dorcas Omisore Babatope Ayodeji Kolawole Adeniyi Sunday Aderibigbe Mathew Alo | 2019 | World Journal of Diabetes2019,10,1: | 8 |
| 2 | Use of ion-exchange resins to prepare 100 μm-sized microcapsules with prolonged drug-release by the Wurster process显示文摘 | Hideki Ichikawa Kazuhiro Fujioka Moji Christianah Adeyeye Yoshinobu Fukumori | 2001 | International Journal of Pharmaceutics2001,,1: | 2 |
| 3 | Montmorillonite surface properties and sorption characteristics for heavy metal removal from aqueous solutions 显示文摘 | Christianah O I Mi H B Dong S K | 2009 | Journal of Hazardous Materials2009,166,7: | 1 |
| 4 | MontmoriUonite surface properties and sorption characteristics for heavy metal removal from aqueous solutions 显示文摘 | Christianah Olakitan Ijagbemi Mi-Hwa Back Dong-Su Kim | 2009 | Journal of Hazardous Materials2009,166,1: | 1 |
| 5 | Use of ion - exchange resins to propare 100μm -sized microcapsules with prolonged drugrelease by the Wurster process显示文摘 | Ichikawa H Fujioka K Christianah M | 2001 | Int J Pharm2001,216,: | 1 |
| 6 | Development and evaluation of sustained-release Ibuprofen-Wax Microsheres Ⅱ in vitro dissolution studies 显示文摘 | Christianah MA and James CP | 1994 | Pharm Research1994,2,4: | 1 |
| 7 | Development and in vivo evaluation of buccal tablets prepared using danazol-sulfobutylether 7 β-cyclodextrin (SBE7) complexes显示文摘 | Jain A C Bruce J A Moji Christianah Adeyeye | 2002 | J Pharmaceutical Sci2002,91,: | 1 |
| 8 | Adsorptive performance of un-calcined sodium exchanged and acid modified montmorillonite for Ni 2+ removal: Equilibrium, kinetics, thermodynamics and regeneration studies显示文摘 | Christianah Olakitan Ijagbemi Mi-Hwa Baek Dong-Su Kim | 2009 | Journal of Hazardous Materials2009,,1: | 1 |
| 9 | Use of ion - exchange resins to preparel00 μm - sized microcapsules with prolonged drug - release by the Wurster process显示文摘 | Hideki Ichikawa Kazuhiro Fujioka Moji Christianah Adeyeye | 2001 | International Journal of Pharmaceuties2001,216,12: | 1 |
| 10 | Montmorillonite surface properties and sorption characteristics for heavy metal removal from aqueous solutions显示文摘 | Christianah Olakitan Ijagbemi Mi-Hwa Baek Dong-Su Kim | 2008 | Journal of Hazardous Materials2008,,1: | 1 |
| 11 | Montmorillonite surface properties and sorption characteristics for heavy metal removal from aqueous solutions显示文摘 | Christianah Olakitan Ijagbemi Mi-Hwa Baek Dong-Su Kim | 2008 | Journal of Hazardous Materials2008,,1: | 1 |
| 12 | A review of complementary and alternative medicine used in cancer care:challenges and prospects显示文摘Cancer is a leading cause of death globally,and most patients with cancers frequently seek for complementary and alternative medicine(CAM)to ameliorate their condition.Some of the available CAM care include:acupuncture,aromatherapy,Ayurvedic medicinal drug,cannabis,chelation remedy,homeopathy,hypnotherapy,massage therapy,naturopathic medication,and conventional Chinese remedy amongst others.Despite the growing use of CAM,the evidence-base for its efficacy and safety is limited.Major challenges confronting the efficient deployment of CAM is lack of standardization and regulation;as well as the demand for more extensive studies to validate their safety and efficacy.Integrative oncology which is the combination of CAM and conventional cancer care is likewise complicated through the potential adverse interactions between CAM options and most cancers drugs.The article serves as a guide for healthcare providers and patients to determine how CAM can be safely integrated into the cancer care paradigm.Taking into account safety concerns,however,more studies need to be conducted to properly evaluate its efficacy.Ultimately,CAM can help cancer patients in achieving greater health and well-being. | Samson Seyi Enitan Godwin Avwioro Esther Ngozi Adejumo Oluwakemi Anike Ladipo Chinenye Alaezi Okorochi Gideon Taiwo Oluwaloye Damilola Christianah Ademola-Kemiki | 2023 | TMR Integrative Medicine2023,7,21: | 0 |