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42篇 您的检索式:作者名="Christoforos"
    题名 作者 年代 出处 被引量
1Clostridium difficile causing acute renal failure: Case presentation and review显示文摘AIM: Clostridium difficile infection is primarily a nosocomial infection but asymptomatic carriers of Clostridium difficile can be found in up to 5% of the general population.Ampicillin, cephalosporins and clindamycin are the antibiotics that are most frequently associated with Clostridium difficile-associated diarrhea or colitis. Little is known about acute renal failure as a consequence of Clostridium difficile-associated diarrhea.METHODS: In this case report, we describe the course of Clostridium difficile-associated diarrhea in an 82-yearold patient developing acute renal failure. Stopping the offending agent and symptomatic therapy brought a rapid improvement of diarrhea and acute renal failure, full recovery was gained 18 d after admission. In a systematic review we looked for links between the two conditions.RESULTS: The link between Clostridium difficilr-associated diarrhea and acute renal failure in our patient was most likely volume depletion. However, in experimental studies a direct influence of Clostridium difficile toxins on renal duct cells could be shown.CONCLUSION: Rapid diagnosis, nonspecific supportive treatment and specific antibiotic treatment, especially in the elderly, may lower excess mortality Clostridium difficile-associated diarrhea and renal failure being possible complications.Jasmin Arrich Gottfried H.Sodeck Gürkan Seng(o|¨)lge Christoforos Konnaris Marcus Müllner Anton N.Laggner Hans Domanovits 2005World Journal of Gastroenterology2005,11,8:15
2Cold dialysis and its impact on renal patients' health:An evidence-based mini review显示文摘Chronic renal disease is associated with advanced age,diabetes,hypertension,obesity,musculoskeletal problems and cardiovascular disease,the latter being the main cause of mortality in patients receiving haemodialysis(HD).Cooled dialysate(35 ℃-36 ℃) is recently employed to reduce the incidence of intradialytic hypotension in patients on chronic HD.The studies to date that have evaluated cooled dialysate are limited,however,data suggest that cooled dialysate improves hemodynamic tolerability of dialysis,minimizes hypotension and exerts a protective effect over major organs including the heart and brain.The current evidence-based review is dealing with the protective effect of cold dialysis and the benefits of it in aspects affecting patients' quality of care and life.There is evidence to suggest that cold dialysis can reduce cardiovascular mortality.However,large multicentre randomized clinical trials are urgently needed to provide further supporting evidence in order to incorporate cold dialysis in routine clinical practice.Giorgos K Sakkas Argiro A Krase Christoforos D Giannaki Christina Karatzaferi 2017World Journal of Nephrology2017,6,3:4
3Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients显示文摘AIM To examine whether hemodialysis(HD) patients with restless legs syndrome(RLS) are subjects of greater fatigue and impaired quality of life(QoL) compared to HD patients without RLS.METHODS Eighty five stable HD patients participated in this study. According to their RLS status, the patients were dividedinto the RLS group(n = 23) and the non-RLS group(n = 62). QoL, fatigue, sleep quality, daily sleepiness and depression symptoms were assessed by using various questionnaires. Finally, biochemical parameters including iron, ferritin, hemoglobin, hematocrit and parathormone were assessed. RESULTS The HD patients with RLS scored worse in all the questionnaires used in the study(P < 0.05). The patients with RLS were more likely to receive the HD therapy on the morning shift, whilst 43.5% of the RLS patients reported to experience the RLS symptoms also during HD. The severity of RLS was correlated with fatigue, depression score and sleep quality(P < 0.05). CONCLUSION HD patients with RLS are subject to lower QoL related parameters and greater fatigue compared to HD patients without RLS. RLS should be successfully managed in order to improve the QoL of the sufferers.Christoforos D Giannaki Michael Hadjigavriel Akis Lazarou Aristos Michael Loukas Damianou Efthimios Atmatzidis Ioannis Stefanidis Georgios M Hadjigeorgiou Giorgos K Sakkas Marios Pantzaris 2017World Journal of Nephrology2017,6,5:3
4Update of endoscopy in liver disease:More than just treating varices显示文摘The management of complications in liver disease is often complex and challenging.Endoscopy has undergone a period of rapid expansion with numerous novel and specialized endoscopic modalities that are of increasing value in the investigation and management of the patient with liver disease.In this review,relevant literature search and expert opinions have been used to provide a brief overview and update of the current endoscopic management of patients with liver disease and portal hypertension.The main areas covered are safety of endoscopy in patients with liver disease,the use of standard endoscopy for the treatment of varices and the role of new endoscopic modalities such as endoscopic ultrasound,esophageal capsule,argon plasma coagulation,spyglass and endomicroscopy in the investigation and treatment of liver-related gastrointestinal and biliary pathology.It is clear that the role of the endoscopy in liver disease is well beyond that of just treating varices.As the technology in endoscopy expands,so does the role of the endoscopist in liver disease.Christoforos Krystallis Gail S Masterton Peter C Hayes John N Plevris 2012World Journal of Gastroenterology2012,18,5:2
5MR motility imaging in Crohn’s disease improves lesion detection compared with standard MR imaging显示文摘Johannes M. Froehlich Christian Waldherr Christoforos Stoupis S. Mehmet Erturk Michael A. Patak 2010European Radiology2010,,:1
6Tenofovir:anucleotideanaloguereverse-transcriptaseinhibitorfortreatment of HIV infectionm显示文摘de Christoforo R Penzak SR 2004Am J Health Syst Pharm2004,61,1:1
7Chromoendoscopy in small bowel capsule endoscopy: Blue mode or Fuji Intelligent Colour Enhancement?显示文摘Christoforos Krystallis Anastasios Koulaouzidis Sarah Douglas John N. Plevris 2011Digestive and Liver Disease2011,,12:1
8Coping with uncertainties through an automated workflow for 3D reservoir modelling of carbonate reservoirs显示文摘Reliable 3D modelling of underground hydrocarbon reservoirs is a challenging task due to the complexity of the underground geological formations and to the availability of different types of data that are typically affected by uncertainties. In the case of geologically complex depositional environments, such as fractured hydrocarbon reservoirs, the uncertainties involved in the modelling process demand accurate analysis and quantification in order to provide a reliable confidence range of volumetric estimations. In the present work, we used a 3D model of a fractured carbonate reservoir and populated it with different lithological and petrophysical properties. The available dataset also included a discrete fracture network(DFN) property that was used to model the fracture distribution. Uncertainties affecting lithological facies, their geometry and absolute positions(related to the fault system), fracture distribution and petrophysical properties were accounted for. We included all different types of uncertainties in an automated approach using tools available in today’s modelling software packages and combining all the uncertain input parameters in a series of statistically representative geological realizations. In particular, we defined a specific workflow for the definition of the absolute permeability according to an equivalent, single porosity approach, taking into account the contribution of both the matrix and the fracture system. The results of the analyses were transferred into a 3D numerical fluid-dynamic simulator to evaluate the propagation of the uncertainties associated to the input data down to the final results, and to assess the dynamic response of the reservoir following a selected development plan. The 'integrated approach' presented in this paper can be useful for all technicians involved in the construction and validation of 3D numerical models of hydrocarbon-bearing reservoirs and can potentially become part of the educational training for young geoscientists and engineers, since an integrated and well-constructed workflow is the backbone of any reservoir study.Christoforos Benetatos Giorgio Giglio 2021Geoscience Frontiers2021,12,6:1
9Tenofovir: a nueleotide analogue reverse-transeriptase inhibitor for treatment of HIV infection 显示文摘De Christoforo R Penzak SR 2004Am J Health Syst Pharm2004,61,1:1
10Failure identification in smart grids based on Petri net modeling 显示文摘Vito Calderaro Christoforos N H Antonio Piccolo 2011IEEE Transactions on Industrial Electronics2011,58,10:1
11New LFN and RTN analysis methodology in 28 and 14 nm FD-SOI MOSFETs 显示文摘CHRISTOFOROS G T 2015Reliability Physics Symposium2015,16,8:1
12Inhibition of hepatic tumor cell proliferation in vitro and tumor growth in vivo by taltobulin,a synthetic analogue of the tripeptide hemiasterlin显示文摘AIM: To investigate the inhibitory effects of taltobulin (HTI-286), a synthetic analogue of natural hemiasterlin derived from marine sponges, on hepatic tumor growth in vitro and in vivo. METHODS: The potential anti-proliferative effects of HTI-286 on different hepatic tumor cell lines in vitro and in vivo were examined. RESULTS: HTI-286 significantly inhibited proliferation of all three hepatic tumor cell lines (mean IC50 = 2 nmol/L ± 1 nmol/L) in vitro. Interestingly, no decrease in viable primary human hepatocytes (PHH) was detected under HTI-286 exposure. Moreover, intravenous administration of HTI-286 significantly inhibited tumor growth in vivo (rat allograft model). CONCLUSION: HTI-286 might be considered a potent promising drug in treatment of liver malignancies. HTI-286 is currently undergoing clinical evaluation in cancer patients.Yogesh K Vashist Celine Tiffon Christoforos Stoupis Claudio A Redaelli 2006World Journal of Gastroenterology2006,12,42:1
13Effects of Etanercept and Minocycline in a rat model of spinal cord injury显示文摘Fabien Marchand Christoforos Tsantoulas Dalbinder Singh John Grist Anna K. Clark Elizabeth J. Bradbury Stephen B. McMahon 2008European Journal of Pain2008,,7:1
14Development of a petroleum knowledge tutorial system for university and corporate training显示文摘The increasingly rapid development of the disciplines of petroleum engineering and petroleum geology has led to new methodologies and interpretation techniques forming new knowledge that should be offered quickly and efficiently to modern engineers and geologists. This need is equally important for students as well as for young professionals. Access and training to all scientific information is necessary to ensure success in their future careers. Today, e-learning has become a common medium for the management and distribution of on-line educational content. Learning Management Systems (LMSs) were not only developed to handle a large variety of multimedia content that provides an organized knowledge repository used to accelerate access to information and skill acquisition; but, LMSs can also keep detailed statistics on the use of the available material offering a powerful training and educational tool. In this document, the Petroleum Knowledge Tutorial System, an LMS platform offering a variety of online educational and training options to petroleum engineers and geologists, is presented. It was created using Moodle, open- source software that can be used to create on-line courses. The platform covers fundamental educational concepts in a structured way. It follows an optimized 'workflow' that can be applied not only to solve a specific exercise but also any similar problem encountered over the course of one's career. The platform was designed to offer a repository of learning material in various forms and to favor user-platform interactions It can be used for training and evaluation purposes through exercises and problem solving that the user can perform online by using browsing software along with Internet access. Special tools were created and implemented on the platform to assist the user in completing a variety of tasks including performing exercises involving calculations with given data and plots of points or lines on graphs without leaving the learning environment. Furthermore, videos with detailed explanations follow each learning module and provide the full solution to every exercise. The LMS automatically keeps a large statistical database including the users' access to activities on the platform that can be exported and further processed to improve the platform functionality and evaluate the users' performance.Verga Francesca Benetatos Christoforos Sacchi Quinto Carta Roberto 2012Petroleum Science2012,9,1:1
15Chromoendoscopy in small bowel capsule endoscopy: Blue mode or Fuji Intelligent Colour Enhancement?显示文摘Christoforos Krystallis Anastasios Koulaouzidis Sarah Douglas John N. Plevris 2011Digestive and Liver Disease2011,,12:1
16A constructive bin-oriented heuristic for the two-dimensional bin packing problem with guillotine cuts 显示文摘Christoforos C Fleszar K 2011Computers & Operations Research2011,38,10:1
17Advanced persistent threat in 3G networks: Attacking the home network from roaming networks 显示文摘CHRISTOS X CHRISTOFOROS N 2014Com- puters Security2014,40,2:1
18A genetic algorithm so- lution approach to the hydrothermal coordination problem显示文摘Christoforos E Anastasios B G John V P B 2004IEEE Transactions on Power Systems2004,19,2:1
19Role of methylenetetrahydrofolate reductase 677C->T polymorphism in the development of premature myocardial infarction显示文摘Loukianos S. Rallidis Argiro Gialeraki Christoforos Komporozos Panagiotis Vavoulis Georgios Pavlakis Anthi Travlou Ioannis Lekakis Dimitrios T. Kremastinos 2007Atherosclerosis2007,,1:1
20Bounds on the number of markings consistent with label observations in Petri Nets显示文摘Christoforos N Hadjicostis Yu Ru 2009IEEE Transactions on Automation Science and Engineering2009,6,2:1
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