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| 1 | 未破裂颅内动脉瘤患者管理指南美国心脏协会/美国卒中协会针对医疗专业人员的指南显示文摘目的这份更新版指南旨在为未破裂颅内动脉瘤患者的管理提供全面的循证建议。方法写作组采用系统文献回顾(1977年1月至2014年6月),参考同期已发表的循证指南、个人文件和专家意见来总结现有的证据,指出现有知识的差距;如果合适,则根据美国心脏协会( American Heart Association, AHA)标准做出推荐。本指南经过了包括卒中委员会领导层以及AHA科学声明监督委员会在内的广泛同行评议,然后由AHA科学咨询和协调委员会审批通过。结果本指南对未破裂颅内动脉瘤患者的医疗诊治提出了循证建议,涉及临床表现、自然史、流行病学、危险因素、筛查、诊断、影像学以及手术和血管内治疗的转归。 | B. Gregory Thompson Robert D. Brown Sepideh Amin-Hanjani Joseph P. Broderick Kevin M. Cockroft E. Sander Connolly Gary R. Duckwiler Catherine C. Harris Virginia J. Howard S. Claiborne (Clay) Johnston Philip M. Meyers Andrew Molyneux Christopher S. Ogilvy Andrew J. Ringer James Torner 肖国栋 徐加平 石际俊 尤寿江 张霞 刘慧慧 曹勇军 | 2015 | 国际脑血管病杂志2015，23，8： | 127 |
| 2 | Role of immunosuppression and tumor differentiation in predicting recurrence after liver transplantation for hepatocellular carcinoma: A multicenter study of 412 patients显示文摘AIM: To assess pre-orthotopic liver transplantation (OLT) factors that could be evaluated pre-operatively or con- trolled post-operatively associated with hepatocellular carcinoma (HCC) recurrence and disease-free survival after liver transplantation (LT).METHODS: Four hundred and twelve patients trans- planted for HCC between 1988 and 1998 in 14 French centers, who survived the postoperative period were studied. Kaplan Meier estimates were calculated for 24 variables potentially associated with recurrence of HCC. Uni- and multivariate analyses were conducted to iden- tify independent predictors of recurrence. RESULTS: Overall 5-year disease-free survival was 57.1%. By univariate analysis, variables associated with disease-free survival were: presence of cirrhosis (P = 0.001), etiology of liver disease (P = 0.03), α fetoprotein level (< 200, 200 to 2000, or > 2000; P < 0.0001), γ-GT activity (N, N to 2N or > 2N; P = 0.02), the number of nodules (1, 2-3 or ≥ 4; P = 0.02), maximal diameter of the largest nodule (< 3 cm, 3 to 5 cm or > 5 cm; P < 0.0001), the sum of the diameter of the nodules (< 3 cm, 3 to 5 cm, 5 to 10 cm or >10 cm; P < 0.0001), bi- lobar location (P = 0.01), preoperative portal thrombosis (P < 0.0001), peri-operative treatment of the tumor (P = 0.002) and chemoembolization (P = 0.03), tumor differentiation (P = 0.01), initial type of calcineurin inhibitor (P = 0.003), the use of antilymphocyte antibodies (P = 0.02), rejection episodes (P = 0.003) and period of LT (P < 0.0001). By multivariate analysis, 6 variables were independently associated with HCC recurrence: maximal diameter of the largest nodule (P < 0.0001), time of LT (P < 0.0001), tumor differentiation (P < 0.0001), use of anti-lymphocyte antibody (ATG) or anti-CD3 antibody (OKT3) (P = 0.005), preoperative portal thrombosis (P = 0.06) and the number of nodules (P = 0.06). CONCLUSION: This study identif ies immunosuppression, through the use of ATG or OKT3, as a predictive factor of tumor recurrence, and confi rms the prognostic value of tumor differentiation. | Thomas Decaens Franoise Roudot-Thoraval Solange Bresson-Hadni Carole Meyer Jean Gugenheim Francois Durand Pierre-Henri Bernard Olivier Boillot Philippe Compagnon Yvon Calmus Jean Hardwigsen Christian Ducerf Georges Philippe Pageaux Sébastien Dharancy Olivier Chazouillères Daniel Cherqui Christophe Duvoux | 2006 | World Journal of Gastroenterology2006，12，45： | 10 |
| 3 | Update on the natural history of intracranial atherosclerotic disease: A critical review显示文摘Intracranial atherosclerotic disease (ICAD) contributes to a significant number of ischemic strokes. There is debate in the recent literature concerning the impact of the location of stenosis in ICAD on outcome. Some reports have suggested that disease processes and outcomes vary by vessel location, potentially altering the natural history and indications for intervention. Here we have performed a comprehensive, critical review of the natural history of ICAD by vessel in an attempt to assess the differences in disease specific to each of the vascular territories. Our assessment concludes that only minor differences exist between patients with different vessels affected in vessel-specific ICAD. We have found that middle cerebral artery disease confers a lower mortality than vessel-specific ICAD in other intracranial vessels, asymptomatic disease follows a more benign course than symptomatic disease, andthat plaque progression or the detection of microemboli on transcranial Doppler may predict poor outcome. Given the expanding indications for treatment of ICAD and rapidly developing endovascular techniques to confront this disease, a thorough understanding of the natural history of ICAD aids the interventional neuroradiologist in determining when to treat and how to predict outcome in this patient population. | Ricardo J Komotar Christopher P Kellner Daniel M Raper Dorothea Strozyk Randall T Higashida Philip M Meyers | 2010 | World Journal of Radiology2010，2，5： | 8 |
| 4 | 动脉瘤性蛛网膜下腔出血患者出血后脑血管痉挛的介入治疗显示文摘本临床实践标准述及动脉瘤性蛛网膜下腔出血患者出血后脑血管痉挛(post—hemorrhagiccerebralvasospasm,PHCV)的介入治疗。这些结论基于神经介入外科学学会的标准委员会的评估,包括使用由美国心脏协会卒中委员会和牛津大学循证医学中心提出的循证医学指南进行的文献回顾。特别关注现有介入治疗方法的安全性和有效性,包括腔内球囊血管成形术(transluminalballoonangioplasty,TBA)和动脉内血管扩张药物输注治疗(intra-arterialvasodilatorinfusiontherapy,IAVT)。评估结果显示,这些侵袭性介入治疗可能有益,并可考虑用于PHCV,如伴有脑缺血症状和最佳的药物治疗无效的患者的治疗。概括起来,IAVT对累及近端和(或)远端颅内脑循环的PHCV可能有益,而TBA则可能对累及近端颅内脑循环的PHCV有益。评估结果显示,对于上述适应证,根据美国心脏协会指南可将TBA和IAVT归为IIb级推荐和B级证据,根据牛津大学循证医学中心指南则可归为4级推荐和C级证据。 | Todd Abruzzo Christopher Moran Kristine A Blacldaam Clifford J Eskey Raisa Lev Philip Meyers Sandra Narayanan Charles Joseph Prestigjacol~ 黄凯滨(译) 吴永明(译) | 2013 | 国际脑血管病杂志2013，21，1： | 4 |
| 5 | Acquired von Willebrand Syndrome in Patients With a Centrifugal or Axial Continuous Flow Left Ventricular Assist Device显示文摘 | Anna L. Meyer Doris Malehsa Ulrich Budde Christoph Bara Axel Haverich Martin Strueber | 2014 | JACC: Heart Failure2014，，2： | 2 |
| 6 | Serum uric acid as an independent predictor of mortality in patients with angiographically proven coronary artery disease显示文摘 | Christoph Bickel Hans J Rupprecht Stefan Blankenberg Gerd Rippin Gerd Hafner Alexander Daunhauer Klaus-Peter Hofmann Jürgen Meyer | 2002 | The American Journal of Cardiology2002，，1： | 2 |
| 7 | Rabbit Hemorrhagic Disease Virus: Genome Organization and Polyprotein Processing of a Calicivirus Studied after Transient Expression of cDNA Constructs显示文摘 | Gregor Meyers Christoph Wirblich Heinz-Jürgen Thiel J?rg Oliver Thumfart | 2000 | Virology2000，，2： | 1 |
| 8 | Understanding Customer Experience 显示文摘 | Christopher Meyer Andre Schwager | 2007 | Harvard Business Review2007，，2： | 1 |
| 9 | Treating thermally injured children suffering symptoms of acute stress with imipramine and fluoxetine: A randomized, double-blind study显示文摘 | Rhonda Robert Win J. Tcheung Laura Rosenberg Marta Rosenberg Charles Mitchell Cynthia Villarreal Christopher Thomas Charles Holzer Walter J. Meyer | 2008 | Burns2008，，7： | 1 |
| 10 | Institutional Culture and Individual Behavior: Creating an Ethical Environment 显示文摘 | Christopher Meyers | 2004 | Science and Engineering Ethics2004，，10： | 1 |
| 11 | Swarm Intelligence: A Whole New Way to Think about Business显示文摘 | | 2001 | Harvard Business Review2001，，5： | 1 |
| 12 | What will replace the Tech Economy显示文摘 | Stan Davis and Christopher Meyer | 2000 | Time2000，155，21： | 1 |
| 13 | The analysis of 5'-mononucleotides in infant formula by HPLC显示文摘 | Christian Perrin Liliane Meyer Claudia Mujahid Christopher J Blake | | 0，，02： | 1 |
| 14 | A COMPARISON OF CYTOLOGY AND FLUORESCENCE IN SITU HYBRIDIZATION FOR THE DETECTION OF UROTHELIAL CARCINOMA显示文摘 | KEVIN C. HALLING WALTER KING IRINA A. SOKOLOVA REID G. MEYER HALEH M. BURKHARDT AMY C. HALLING JOHN C. CHEVILLE THOMAS J. SEBO SANJAY RAMAKUMAR CHRISTOPHER S. STEWART SHANE PANKRATZ DENNIS J. O’KANE STEVEN A. SEELIG MICHAEL M. LIEBER ROBERT B. JENKINS | 2000 | The Journal of Urology2000，，5： | 1 |
| 15 | Bone loading pattern around implants in average and atrophic edentulous maxillae: a finite-element analysis 显示文摘 | Meyer U Vollmer D Christoph B | 2001 | J Cranio-Maxillofac Surg2001，29，2： | 1 |
| 16 | Systemic Spread Is an Early Step in Breast Cancer显示文摘 | Yves Hüsemann Jochen B. Geigl Falk Schubert Piero Musiani Manfred Meyer Elke Burghart Guido Forni Roland Eils Tanja Fehm Gert Riethmüller Christoph A. Klein | 2008 | Cancer Cell2008，，1： | 1 |
| 17 | The analysis of 5′-mononucleotides in infant formulae by HPLC显示文摘 | Christian Perrin Liliane Meyer Claudia Mujahid Christopher J Blake | 2001 | Food Chemistry2001，，2： | 1 |
| 18 | Relation of markers of inflammation (C-reactive protein, fibrinogen, von Willebrand factor, and leukocyte count) and statin therapy to long-term mortality in patients with angiographically proven coronary artery disease显示文摘 | Christoph Bickel Hans J Rupprecht Stefan Blankenberg Christine Espiniola-Klein Axel Schlitt Gerd Rippin Gerd Hafner Rainer Treude Hisham Othman Klaus-Peter Hofmann J.ürgen Meyer | 2002 | The American Journal of Cardiology2002，，8： | 1 |
| 19 | Survival and Recurrence Rates after Resection for Hepatocellular Carcinoma in Noncirrhotic Livers显示文摘 | Hauke Lang Georgios C. Sotiropoulos Eirini I. Brokalaki Klaus Jürgen Schmitz Christian Bertona Gabriele Meyer Andrea Frilling Andreas Paul Massimo Malagó Christoph E. Broelsch | 2007 | Journal of the American College of Surgeons2007，，1： | 1 |
| 20 | What will replace the Tech Economy 显示文摘 | Stan Davis and Christopher Meyer | 2000 | Time2000，155，21： | 1 |
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