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408篇 您的检索式:作者名="Chua R"
    题名 作者 年代 出处 被引量
15-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages显示文摘5-Hydroxymethylcytosine (5hmC ) 是被连接了到基因规定和癌症致病的重要哺乳动物的 DNA epigenetic 修正。这里,我们用定序途径的一枝敏感化学基于标签的低输入的猎枪在传播没有房间的 DNA (cfDNA ) 探索了 5hmC 的诊断潜力。我们从七种不同癌症类型的 49 个病人定序没有房间的 5hmC 并且发现了能被用来与高精确性预言癌症类型和阶段的不同特征。明确地,我们发现肺癌症在 cfDNA 导致 5hmC 的进步全球损失,而 hepatocellular 癌和胰腺的癌症在没有房间的 hydroxymethylome 导致疾病特定的变化。我们的 proof-of-principle 结果建议没有房间的 5hmC 签名可以潜在地被使用不仅识别癌症类型而且在一些癌症追踪肿瘤舞台。Chun-Xiao Song Senlin Yin Li Ma Amanda Wheeler Yu Chen Yan Zhang Bin Liu Junjie Xiong Weihan Zhang Jiankun Hu Zongguang Zhou Biao Dong Zhiqi Tian Stefanie S Jeffrey Mei-Sze Chua Samuel So Weimin Li Yuquan Wei Jiajie Diao Dan Xie Stephen R Quake 2017Cell Research2017,27,10:17
2Induced anisotropy in a sand显示文摘Arthur J R F Chua K S Dunstan T 1977Geotechnique1977,27,1:2
3Modulation of adhesion molecules and monocyte chemoattractant protein by tumor necrosis factor-sand salicylic acid in primary human coronary attery endothelial cells显示文摘Chua PK Yanagihara R Melish ME 2003Cell Mol Biol2003,49,7:1
4Clarifying chaos:Examples and counterexamples显示文摘Brown R Chua L O 1996International Journal of Bifurcation and Chaos1996,6,2:1
5From the Head and the Heart: Locating Cognition-and Affect- based Trust in Managers' Professional Networks显示文摘CHUA R Y J INGRAM P MORRIS M 2008Academy of Management Journal2008,,:1
6The effect of vascular access location and size on circuit survival in pediatric continuous renal replacement therapy:a report from the PPCRRT registry显示文摘Hackbarth R Bunchman TE Chua AN 0,,12:1
7The RNA splicing factor hslu7 is required for correct 3' splice site choice显示文摘 REED R 1999Nature1999,402,:1
8Functional dissection of SIRT6 : identification of domains that regulate histone deacetylase activity and chromatin localization显示文摘Tennen R I Berber E Chua K F 2010Mech Ageing Dev2010,131,3:1
9Weatherability of coated fabrics as roofing material in tropical environment显示文摘ABDUL R H CHUA C S TOYODA H 2004Building and Environment2004,,39:1
10Label-free direct detection of MiRNAs with silicon nanowire biosensors 显示文摘Zhang G J Chua J H Chee R E 2009Biosens Bioelectron2009,24,8:1
11Point signatures: a new representation for 3d object recognition 显示文摘Chua C J R 1997Internalional Journal of Computer Vision1997,25,1:1
12Induced anisotropy in sand显示文摘Arthur J R F Chua K S Dunstan T 1977Geotechnique1977,27,1:1
13Cancer test is genes are coordinately expressed and are markers of poor outcome in non - small cell lung cancer 显示文摘GURE A O CHUA R WILLIAMSON B 2005Clin Cancer R es2005,11,22:1
14Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer显示文摘Gure AO Chua R Williamson B 0,,22:1
15Genomic instability and aging-like phenotype in the absence of mamma- lian SIRT6 显示文摘Mostoslavsky R Chua KF Lombard DB 2006Cell2006,124,2:1
16Induced anisotropy in a sand显示文摘Arthur J R F Chua K S Dunstan T 1977Geotechnique1977,27,1:1
17Point signatures: A new representation for 3D object recognition 显示文摘Chua C S Jarvis R 1997International Journal of Computer Vision1997,25,1:1
18Plant bZIP proteins gather at ACGT elements显示文摘Foster R Izawa T Chua N H 1994The FASEB Journal1994,8,2:1
19Cancer testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer 显示文摘GURE A O CHUA R WILLIAMSON B 2005Clin Cancer Res2005,11,22:1
20Locating cog- nition- and affect-based trust in managers' Professional Networks显示文摘Chua R J lngram M W Morris M W 2008Academy of Management Journal2008,1,3:1
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