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| 1 | MiR-33a suppresses breast cancer cell proliferation and metastasis by targeting ADAM9 and ROS1显示文摘MicroRNAs (miRNAs ) 是由指向多重 mRNAs 的定序明确地在基因表示的 post-transcriptional 规定有一个枢轴的角色的小 noncoding RNA。尽管 miR-33a 最近被报导在类脂化合物动态平衡,动脉粥样硬化,和肝的纤维变性起一个重要作用,在肿瘤前进和转移的 miR-33a 的功能大部分是未知的。这里,我们发现在乳癌纸巾的 downregulated miR-33a 与淋巴节点转移相关。MiR-33a 表示比 noncancerous 胸在高度变形的乳癌房间线是显著地更低的上皮的房间和非变形的乳癌房间。而且,在变形乳癌细胞的 miR-33a 的 overexpression 显著地减少在 vitro 并且显著地的细胞增长和侵略在 vivo 禁止肿瘤生长和肺转移,而它的在非变形的乳癌细胞击倒显著地在 vitro 提高细胞增长和侵略并且在 vivo 支持肿瘤生长和肺转移。联合生物信息学预言和生物化学的分析,我们证明 ADAM9 和 ROS1 是 miR-33a 的直接下游的目标。这些调查结果作为乳癌房间增长和转移的一个否定管理者识别了 miR-33a。 | Chuankai Zhang Yunda Zhang Weiji Ding Yancheng Lin Zhengjie Huang Qi Luo | 2015 | Protein & Cell2015，6，12： | 10 |
| 2 | Landing site topographic mapping and rover localization for Chang’e-4 mission显示文摘This paper presents the techniques and results of landing-site topographic mapping and rover localization using orbital,descent and rover images in the Chang’e-4 mission.High-resolution maps of the landing site are generated from orbital and descent images.Local digital elevation models and digital orthophoto maps with 0.02 m resolution are generated at each waypoint.The location of the lander is determined as(177.588?E,45.457?S)using festure-matching techniques.The cross-site visual localization method is routinely used to localize the rover at each waypoint to reduce error accumulation from wheel slippage and IMU drift in dead reckoning.After the first five lunar days,the rover travels 186.66 m from the lander,according to the cross-site visual localization.The developed methods and results have been directly utilized to support the mission’s operations.The maps and localization information are also valuable for supporting multiple scientific explorations of the landing site. | Zhaoqin LIU Kaichang DI Jian LI Jianfeng XIE Xiaofeng CUI Luhua XI Wenhui WAN Man PENG Bin LIU Yexin WANG Sheng GOU Zongyu YUE Tianyi YU Lichun LI Jia WANG Chuankai LIU Xin XIN Mengna JIA Zheng BO Jia LIU Runzhi WANG Shengli NIU Kuan ZHANG Yi YOU Bing LIU Jiangang LIU | 2020 | Science China(Information Sciences)2020，63，4： | 3 |
| 3 | Grain refinement in an as-cast AZ61 magnesium alloy processed by multi-axial forging under the multitemperature processing procedure显示文摘 | Qiang Chen Dayu Shu Chuankai Hu Zude Zhao Baoguo Yuan | 2012 | Materials Science & Engineering A2012，，： | 2 |
| 4 | Characterization of hot deformation behavior of as-extruded Mg–Gd–Y–Zn–Zr alloy显示文摘 | Xiangsheng Xia Qiang Chen Jianping Li Dayu Shu Chuankai Hu Shuhai Huang Zude Zhao | 2014 | Journal of Alloys and Compounds2014，，： | 2 |
| 5 | Nonsingular terminal sliding mode con- trol of robot manipulators using fuzzy wavelet net- works显示文摘 | Lin Chuankai | 2006 | IEEE Transactions on Fuzzy Systems2006，14，6： | 1 |
| 6 | Grain refinement in an as-cast AZ61 magnesium alloy processed by multi-axial forging under the multi temperature processing procedure显示文摘 | Chen Qiang Shua Dayu Hua Chuankai | 2012 | Materials Science and Engineering:A2012，541，15： | 1 |
| 7 | Grain refinement in an as-cast AZ61 magnesium alloy processed by multi-axial forging under the multitemperature processing procedure显示文摘 | Qiang Chen Dayu Shu Chuankai Hu Zude Zhao Baoguo Yuan | 2012 | Materials Science & Engineering A2012，，： | 1 |
| 8 | Grain refine- ment in an as-cast AZ61 magnesium alloy processed by mul- ti-axial forging under the multi temperature processing proce- dure显示文摘 | Chen Qiang Hua Dayu Hua Chuankai | 2012 | Materials Science and Engineering:A2012，541，15： | 1 |
| 9 | Microstructural evolution and tensile mechanical properties of AM60B magnesium alloy prepared by the SIMA route显示文摘 | Zude Zhao Qiang Chen Zejun Tang Chuankai Hu | 2010 | Journal of Alloys and Compounds2010，，1： | 1 |
| 10 | Nonsingular terminal sliding mode control of robot manipulators using fuzzy wavelet networks显示文摘 | Lin Chuankai | 2006 | IEEE Transactions on Fuzzy Systems2006，14，6： | 1 |
| 11 | Grain refinement in an as-cast AZ61magnesium alloy processed by multi-axialforging under the multi temperature processing procedure 显示文摘 | Qiang Chen Dayu Shua Chuankai Hua | 2012 | Materials Science and Engineering: A2012，541，15： | 1 |
| 12 | Grain refinement in an as-cast AZ61 magnesium alloy processed by multi-axial forging under the multitemperature processing procedure 显示文摘 | Chen Qiang Shu Dayu Hu Chuankai | 2012 | Materials Science and Engineering A2012，541，： | 1 |
| 13 | Grain refinement in an as-cast AZ61magnesium alloy processed by multi-axial forging under the multi temperature processing procedure 显示文摘 | Qiang Chen Dayu Shua Chuankai Hua | 2012 | Materials Science and Engineering : A2012，541，15： | 1 |
| 14 | A MEMS micromirror driven by electrostatic force 显示文摘 | Hu Fangrong Yao Iun Qiu Chuankai | 2010 | Journal of Electrostatics2010，68，3： | 1 |
| 15 | Grain Refinement in an as-cast AZ61 magnesium alloy processed by multi-axial forging under the multitemperature processing procedure 显示文摘 | Chen Qiang Shu Dayu Hu Chuankai | 2012 | Materials Science and Engineering A2012，541，： | 1 |
| 16 | Grain refinement in an as-cast AZ61magnesium alloy processed by multi-axial forging under the multi temperature processing procedure显示文摘 | Chen Qiang Shua Dayu Hua Chuankai | 2012 | Materials Science and Engineering:A2012，541，15： | 1 |
| 17 | Ordnance Material Science and Engineering显示文摘 | Xiao Bing Kang Feng Hu Chuankai | 2011 | 43(1):942011，43，1： | 1 |
| 18 | Grain refinement in an as-cast AZ61magnesium alloy processed by multi-axial forging under the multi temperature processing procedure 显示文摘 | Chen Qiang Shua Dayu Hua Chuankai | 2012 | Materials Science and Engineering:A2012，541，15： | 1 |
| 19 | Grain refinement in an as-cast AZ61magnesium alloy processed by multi-axial forging under the multi temperature processing procedure 显示文摘 | Qiang Chen Dayu Shua Chuankai Hua | 2012 | Materials Science and Engineering :A2012，541，15： | 1 |
| 20 | Grain refinement in an as-cast AZ61magnesium alloy processed by multi-axial forging under the multi temperature processingprocedure 显示文摘 | Qiang Chen Dayu Shua Chuankai Hua | 2012 | Materials Science and Engineering A2012，541，15： | 1 |
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