|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Antimalarial potency of the leaf extract of Aspilia africana(Pers.) C.D.Adams显示文摘Objective:To investigate the antimalarial activity of ethanol extract of Aspilin africana (A.africana) leaf.Methods:The ethanol extract of A.africana leaf(100-400 mg/kg) was screened for blood schizonticidal effect against chloroquine-sensitive Plasmodium berghei(P. berghei) in mice both in early and established models of antimalarial studies.Results:The leaf extract exhibited significant(P<0.05) antiplasmodial activity in 4-day early infection and in established infection tests with a considerable mean survival time comparable to that of standard drug,chloroquine(10 mg/kg).Conclusions:The findings show thai ethanol extract of A.africana leaf possesses potent antiplasmodial activity which justify the use in ethnomedicine and can be developed in malaria therapy. | Akuodor Godwin Christian Amos Grace Mfon Essien Augustine Dick Essien David-Oku Akpan Joseph Linus Ezeokpo Basil Chukwuma | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，2： | 2 |
| 2 | 伊莫州奥韦里地区技术工人眼部疾病患病率及类型调查分析(英文)显示文摘目的:评估技术工人眼部疾病患病率及模式,向有关部门建议施行必要政策以保护技术工人眼部健康。方法:描述性横断面研究。采用比例抽样技术和随机简单抽样法进行样本选择。结果:技术工人中退行性结膜疾病并伴有睑裂黄斑以30.1%患病率高居第一。汽车工中结膜性疾病、角膜混浊、过敏性结膜炎发病率较高。表体异物是与工伤有关的最常见的损伤,而13.6%的工人由此发展为白内障。结论:政府应该施行可以保护技术工人眼部健康的政策。 | Joseph Chukwuma Eziechila Eberechukwu Ogbeanu Achigbu Sebastian Ntuko Nwosu Omobolake Tolutope Edema | 2017 | 国际眼科杂志2017，17，11： | 2 |
| 3 | Acute and subacute oral toxicity study on the flavonoid rich fraction of Monodora tenuifolia seed in albino rats显示文摘Objective:To investigate the effects of the flavonoid rich fraction of Monodora tenuifolia seed on the haematology,histopathology and liver profile of Wistar albino rats.Methods:Toxicity study was investigated on the flavonoid rich fraction of Monodora tenuifolia in rats administered different concentrations orally for 28 d using standard laboratory procedures.Results:The LD_(50)of the flavonoid rich fraction was found to be above 5000 mg/kg body weight in mice observed for 48 h.After the Day 14,biochemical markers of liver injury such as serum alanine aminotransferase,and aspartate aminotransferase decreased significantly(P<0.05 at doses of 100 and 200 mg/kg body weight and P<0.01 at 400 mg/kg)while serum alkaline phosphatase increased non-significantly(P>0.05).There was non-significant(P>0.05)effect observed across the groups in the levels of serum total protein,albumin,globulin,urea and creatinine.The result of histological examination showed various degrees of peribiliary hepatitis after the Day 14 which fizzled out after the Day 28.Conclusions:The result therefore suggests that the seed extract is potentially safe. | Raphael Chukwuma Ekeanyanwu Obioma Uzoma Njoku | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，3： | 2 |
| 4 | Bmi-1 is induced by the Epstein-Barr virus oncogene LMP1 and regulates the expression of viral target genes in Hodgkin lymphoma cells 显示文摘 | Dutton A Woodman CB Chukwuma MB | 2007 | Blood2007，109，6： | 1 |
| 5 | Bmi-1 is induced by the Epstein-Barr virus oncogene LMP1 and regulates the expression of viral target genes in Hodgkin lymphoma cells 显示文摘 | Dutton A Woodman CB Chukwuma MB | 2007 | Blood2007，109，6： | 1 |
| 6 | Trends in the prevalence, awareness, treatment and con- trol of hyperlension:the WHO MONICA Project显示文摘 | Antikainen RL Mohchano VA chukwuma C | 2006 | Eu- ropean JoumaI of cardiovascuIar Prevention and Reha- bilitation2006，13，1： | 1 |
| 7 | Bmi1 is induced by the Epstein-Barr virus oncogen LMP1 and regulates the expression of viral target genes in Hodgkin lymphoma cells显示文摘 | Dutton A Woodman C B Chukwuma M A | 2007 | Blood2007，109，6： | 1 |
| 8 | Diabetes and the risk of stroke显示文摘 | Chukwuma CS Tuomilento J | 1993 | Diabetes Complication1993，7，4： | 1 |
| 9 | Bmi-1 is induced by the Epstein-Barr virus oncogene LMP1 and regulates the expression of viral target genes in Hodgkin lyrn- phoma cells显示文摘 | DUTTON A WOODMAN C B CHUKWUMA M B | 2007 | Blood2007，109，6： | 1 |
| 10 | Bmi-1 is induced by the Epstein-Barr vires oncogene LMP1 and regulates the expression of viral target genes in Hodgkin lymphoma cells显示文摘 | Dutton A Woodman CB Chukwuma MB | 2007 | Blood2007，109，6： | 1 |
| 11 | 2D Finite Element Computer Analysis of Strength for Brazed Joint of Cemented Carbide and Silver Brazing Filler Metal显示文摘 | Meribe Richard Chukwuma Kazuya MORI Kento Takenouchi Yuki Fijishita Takeshi Eguchi Kazufumi Sakata | 2016 | Journal of Mechanics Engineering and Automation2016，6，4： | 1 |
| 12 | Hepatitis C Virus Screening and Management of Seroconversions in Hemodialysis Facilities显示文摘 | Chukwuma Mbaeyi Nicola D. Thompson | 2013 | Semin Dial2013，，4： | 1 |
| 13 | Trends in the prevalence, awareness, treatment and control o hypertension : the WHOMONICA Project显示文摘 | Antikainen R L Moltchanov V A Chukwuma S C | 2006 | Eur J Cardiovasc Prev Rehabi2006，，13： | 1 |
| 14 | Latent Cytomegalovirus Infection Exacerbates Experimental Colitis显示文摘 | Chukwuma Onyeagocha Mohammad S. Hossain Amrita Kumar Rheinallt M. Jones John Roback Andrew T. Gewirtz | 2009 | The American Journal of Pathology2009，，5： | 1 |
| 15 | Flavonoid-rich fraction of the Monodora tenuifolia seed extract attenuates behavioural alterations and oxidative damage in forced-swim stressed rats显示文摘The antidepressant effects of the flavonoid-rich fraction of Monodora tenuifolia seed extract were examined by assessing the extent of attenuation of behavioural alterations and oxidative damage in the rats that were stressed by forced swim test. Compared with the model control group, the altered behavioural parameters were attenuated significantly(P < 0.05) in the group treated with the flavonoid-rich fraction(100 and 200 mg·kg-1), comparable to the group treated with the standard drug, fluoxetine(10 mg·kg-1). The flavonoid-rich fraction and fluoxetine improved significantly(P < 0.05) the activities of the antioxidant enzymes such as superoxide dismutase and catalase as well as other biochemical parameters such as reduced glutathione, protein, and nitrite in the brain of the stressed rats. These results suggested that the flavonoid-rich fraction of Monodora tenuifolia seed extract exerted the antidepressant-like effects which could be useful in the management of stress induced disease. | EKEANYANWU Raphael Chukwuma NJOKU Obioma Uzoma | 2015 | Chinese Journal of Natural Medicines2015，13，3： | 1 |
| 16 | Trends in the prevalence,awareness,treatment and control of hypertension:the WHO MONICA Project显示文摘 | Antikainen RL Moltchanov VA Chukwuma C Sr | 2006 | Eur J Cardiovasc Prev Rehabil2006，13，： | 1 |
| 17 | Bmi-1 is induced by the Epstein-Barr virus oncogene LMP1 and regulates the expression of viral target genes in Hodgkin lymphoma cells显示文摘 | DUTTON A WOODMAN C B CHUKWUMA M B | 2007 | Blood2007，109，6： | 1 |
| 18 | Envionmental impact assessment of de- velopment projects and natural resources -A viepoint 显示文摘 | Chrysanthus Chukwuma Sr | 1996 | Journal of Envionmental Studies1996，，： | 1 |
| 19 | Trends in the prevalence, awareness, treatment and control of hypertension:the WHO MONICA Project 显示文摘 | Antikalnen RL Moltchano VA Chukwuma C | 2006 | European Journal of Cardiovascular Prevention and Rehabilitation2006，13，1： | 1 |
| 20 | Trends in the preva-lence,awareness,treatment and control of hypertension:the WHO MONICA Project显示文摘 | Antikainen RL Moltchanov VA Chukwuma Sr C | 2006 | Eur J Cardiovasc Prev Rehabil2006，13，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员