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| 1 | Preliminary engineering application of microseismic monitoring technique to rockburst prediction in tunneling of Jinping Ⅱ project显示文摘Monitoring and prediction of rockburst remain to be worldwide challenges in geotechnical engineering.In hydropower,transportation and other engineering fields in China,more deep,long and large tunnels have been under construction in recent years and underground caverns are more evidently featured by 'long,large,deep and in group',which bring in many problems associated with rock mechanics problems at great depth,especially rockburst.Rockbursts lead to damages to not only underground structures and equipments but also personnel safety.It has been a major technical bottleneck in future deep underground engineering in China.In this paper,compared with earthquake prediction,the feasibility in principle of monitoring and prediction of rockbursts is discussed,considering the source zones,development cycle and scale.The authors think the feasibility of rockburst prediction can be understood in three aspects:(1) the heterogeneity of rock is the main reason for the existence of rockburst precursors;(2) deformation localization is the intrinsic cause of rockburst;and(3) the interaction between target rock mass and its surrounding rock mass is the external cause of rockburst.As an engineering practice,the application of microseismic monitoring techniques during tunnel construction of Jinping II Hydropower Station was reported.It is found that precursory microcracking exists prior to most rockbursts,which could be captured by the microseismic monitoring system.The stress concentration is evident near structural discontinuities(such as faults or joints),which shall be the focus of rockburst monitoring.It is concluded that,by integrating the microseismic monitoring and the rock failure process simulation,the feasibility of rockburst prediction is expected to be enhanced. | Chun'an Tang Jimin Wang Jingjian Zhang | 2010 | Journal of Rock Mechanics and Geotechnical Engineering2010，2，3： | 32 |
| 2 | Treatment strategies using adefovir dipivoxil for individuals with lamivudine-resistant chronic hepatitis B显示文摘AIM:To investigate retrospectively the long-term efficacy of various treatment strategies using adefovir dipivoxil(adefovir) in patients with lamivudine-resistant chronic hepatitis B.METHODS:We included 154 consecutive patients in two treatment groups:the 'add-on' group(n = 79),in which adefovir was added to ongoing lamivudine treatment due to lamivudine resistance,and the 'switch/combination' group(n = 75),in which lamivudine was first switched to adefovir and then re-added later as needed.The 'switch/combination' group was then divided into two subgroups depending on whether participants followed(group A,n = 30) or violated(group B,n = 45) a proposed treatment strategy that determined whether to add lamivudine based on the serum hepatitis B virus(HBV) DNA levels(< 60 IU/mL or not) after 6 mo of treatment(roadmap concept).RESULTS:The cumulative probability of virologic response(HBV DNA < 60 IU/mL) was higher in group A than in the 'add-on' group and in group B(P < 0.001).In contrast,the cumulative probability of virologic breakthrough was lower in the 'add-on' group than in group B(P = 0.002).Furthermore,the risk of virologic breakthrough in the multivariate analysis was significantly lower in the 'add-on' group than in group A(hazard ratio = 0.096;95%CI,0.015-0.629;P = 0.015).CONCLUSION:The selective combination of adefovir with lamivudine based upon early treatment responses increased the odds of virologic breakthrough relative to the use of uniform combination therapy from the beginning of treatment. | Tae Jung Yun Jin Yong Jung Chang Ha Kim Soon Ho Um Hyonggin An Yeon Seok Seo Jin Dong Kim Hyung Joon Yim Bora Keum Yong Sik Kim Yoon Tae Jeen Hong Sik Lee Hoon Jai Chun Chang Duck Kim Ho Sang Ryu | 2012 | World Journal of Gastroenterology2012，18，47： | 19 |
| 3 | An efficient method to synthesize HMX by nitrolysis of DPT with N_2O_5 and a novel ionic liquid显示文摘A novel polyethylene glycol(PEG)-200-based dicationic acidic ionic liquid(PEG_(200)-DAIL) was used to synthesize HMX from DPT by nitrolysis with N_2O_5.It was found that either N_2O_5 or PEG_(200)-DAIL could improve the yield.Furthermore,the combined use of PEG_(200)-DAIL and N_2O_5 could increase the yield of HMX to 64%with the used quantity of HNO_3 decreased dramatically. | Hui Zhen Zhi Jun Luo Guang An Feng Chun Xu Lv | 2009 | Chinese Chemical Letters2009，20，4： | 15 |
| 4 | The Arabidopsis PARAQUAT RESISTANT2 gene encodes an S-nitrosoglutathione reductase that is a key regulator of cell death显示文摘S-nitrosoglutathione (GSNO ) 的新陈代谢,主要生物学上活跃的氮的氧化物(没有) 种类,被进化地保存的 GSNO reductase (GSNOR ) 催化。以前的研究证明 Arabidopsis GSNOR1/HOT5 基因调整水杨酸酸由 modulating 发信号和 thermotolerance 细胞内部的 S-nitrosothiol 水平。这里,我们报导 Arabidopsis paraquat resistant2-1 (par2-1 ) 的描述显示出反房间死亡显型的异种。当由 paraquat (1,1'-dimethyl-4,4'-bipyridinium 二氯化物) 对待时,在 par2-1 的 superoxide 的生产比得上野类型的植物的,建议 PAR2 调整房间死亡的 superoxide 下游地行动。PAR2,由位置的克隆识别了,被显示与 GSNOR1/HOT5 相同。par2-1 异种在高度保存的 glycine 带一个错误感觉变化,它使变异的蛋白质变为不稳定。比作野类型, par2-1 异种有一不更高铺平,由与 4,5-diaminofluorescein diacetate 染色揭示了。与这结果一致,对待与的野类型的植物一没有施主显示抵抗到 paraquat。有趣地, GSNOR1/HOT5/PAR2 蛋白质水平除它的不变的 mRNA 水平以外,被 paraquat 导致,但是被没有施主减少。一起拿,这些结果建议 GSNOR1/HOT5/PAR2 在通过 modulating 在植物房间调整房间死亡起一个重要作用细胞内部没有水平。 | Ruiqiang Chen Shulan Sun Chun Wang Yansha Li Yan Liang Fengying An Chao Li Haili Dong Xiaohui Yang Jian Zhang Jianru Zuo | 2009 | Cell Research2009，19，12： | 14 |
| 5 | Applications of rock failure process analysis (RFPA) method显示文摘Brittle failure of rocks is a classical rock mechanical problem.Rock failure not only involves initiation and propagation of single crack,but also is associated with initiation,propagation and coalescence of many cracks.The rock failure process analysis(RFPA)tool has been proposed since 1995.The heterogeneity of rocks at a mesoscopic level is considered by assuming that the material properties follow the Weibull distribution.Elastic damage mechanics is used for describing the constitutive law of the meso-level element.The finite element method(FEM)is employed as the basic stress analysis tool.The maximum tensile strain criterion and the Mohr-Coulomb criterion are utilized as the damage threshold.In order to solve the stability problem related to rock engineering structures,fundamental principles of strength reduction method(SRM)and gravity increase method(GIM)are integrated into the RFPA.And the acoustic emission(AE)event rate is employed as the criterion for rock engineering failure.The prominent feature of the RFPA-SRM and RFPA-GIM for stability analysis of rock engineering is that the factor of safety can be obtained without any presumption for the shape and location of the failure surface.In this paper,several geotechnical engineering applications that use the RFPA method to analyze their stability are presented to provide some references for relevant researches.The principles of the RFPA method in engineering are introduced firstly,and then the stability analysis of tunnel,slope and dam is focused on.The results indicate that the RFPA method is capable of capturing the mechanism of rock engineering stability and has the potential for application in a larger range of geo-engineering. | Chun'an Tang Shibin Tang | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，4： | 14 |
| 6 | Efficient one-pot synthesis of n-butyl levulinate from carbohydrates catalyzed by Fe_2(SO_4)_3显示文摘Butyl levulinate(BL) is a promising new candidate as diesel fuel and fuel additive. In this study, an efficient process for a one-pot synthesis of BL from biomass-derived carbohydrates in butanol medium with the catalysis of metal sulfates was developed. The catalytic activity of a series of metal sulfates for the synthesis of BL from fructose was investigated. Among various metal sulfates, ferric sulfate Fe_2(SO_4)_3 was found to be the most efficient catalyst, which gave a remarkably high BL yield of 62.8 mol% under the conditions of 463 K, 3 h, a catalyst dosage of 5.0 g/L, and fructose concentration of 25 g/L. Different carbohydrates including glucose, cellulose, inulin and sucrose were also used for one-pot synthesis of BL with the catalysis of Fe_2(SO_4)_3, showing the yields of 39.6, 30.5, 56.6 and 50.1 mol%, respectively. In addition,the recycling and reuse of Fe_2(SO_4)_3 was studied by characterizing them using powder X-ray diffraction(XRD), scanning electron microscope(SEM), X-ray photoelectron spectroscopy(XPS). A plausible reaction pathway for the one-pot synthesis of BL from fructose was proposed. This study provides a facile and feasible way for the synthesis of BL from biomass. | Ran An Guizhuan Xu Chun Chang Jing Bai Shuqi Fang | 2017 | Journal of Energy Chemistry2017，26，3： | 8 |
| 7 | Synthesis and Characterization of Sphere-like Pt Nanoparticles Supported on DWCNT/WO_3 Nanorods with Electrocatalytic Activity显示文摘Tungsten oxide(WO3) nanorods, which were used to load platinum(Pt) nanoparticles, were investigated. H2WO4 nanorods with diameters from 10 to 50 nm were obtained when tungsten precursor was added into homogenous double-walled carbon nanotubes(DWCNT) and ethylene glycol(EG) solution.Nanosized rod-like WO3 were achieved after calcination of the DWCNT/H2WO4 composite. Sphere-like Pt nanoparticles were loaded on the surface of the nanorods by EG in-situ reduction. Pt particles were isolated by DWCNT/WO3 nanorods and secondary accumulation could be prevented when Pt particles appeared in the DWCNT/WO3 nanorod/EG dispersion solution. Therefore, Pt nanoparticles with mean diameters of 2–6 nm could be obtained. Pt-deposited on DWCNT/WO3 nanorods exhibited high electrochemical activity, which could facilitate the low-cost mass production of Pt catalyst. | Yanhong Yin Chun'an Ma Ziping Wu Man Zhao Litao Chen Youqun Chu | 2015 | Journal of Materials Science & Technology2015，31，9： | 4 |
| 8 | Microseismic monitoring and numerical simulation on the stability of high-steep rock slopes in hydropower engineering显示文摘For high-steep slopes in hydropower engineering, damage can be induced or accumulated due to a series of human or natural activities, including excavation, dam construction, earthquake, rainstorm, rapid rise or drop of water level in the service lifetime of slopes. According to the concept that the progressive damage(microseismicity) of rock slope is the essence of the precursor of slope instability, a microseismic monitoring system for high-steep rock slopes is established. Positioning accuracy of the monitoring system is tested by fixed-position blasting method. Based on waveform and cluster analyses of microseismic events recorded during test, the tempo-spatial distribution of microseismic events is analyzed.The deformation zone in the deep rock masses induced by the microseismic events is preliminarily delimited. Based on the physical information measured by in situ microseismic monitoring, an evaluation method for the dynamic stability of rock slopes is proposed and preliminarily implemented by combining microseismic monitoring and numerical modeling. Based on the rock mass damage model obtained by back analysis of microseismic information, the rock mass elements within the microseismic damage zone are automatically searched by finite element program. Then the stiffness and strength reductions are performed on these damaged elements accordingly. Attempts are made to establish the correlation between microseismic event, strength deterioration and slope dynamic instability, so as to quantitatively evaluate the dynamic stability of slope. The case studies about two practical slopes indicate that the proposed method can reflect the factor of safety of rock slope more objectively. Numerical analysis can help to understand the characteristics and modes of the monitored microseismic events in rock slopes. Microseismic monitoring data and simulation results can be used to mutually modify the sensitive rock parameters and calibrate the model. Combination of microseismic monitoring and numerical simulation provides a more objective basis for the numerical model and parameters and a solid mechanical foundation for the microseismic monitoring. | Chun’an Tang Lianchong Li Nuwen Xu Ke Ma | 2015 | Journal of Rock Mechanics and Geotechnical Engineering2015，7，5： | 4 |
| 9 | Synthesis of 7-Ethyl-10-hydroxycamptothecin and Proposed Reaction Mechanism显示文摘The improved 3 step preparation of a key antitumor agent, 7 ethyl 10 hydroxycamptothecin(SN 38), which consists of ethylation, oxidation and photo chemical rearrangement, is described. The proposed reaction mechanism is also discussed. | LEI Ying jie *, ZHU Chun hua, WANG Zuo quan and LIU Hong (Xian Modern Chemistry Research Institute, Xian 710065, P.R. China) | 2001 | Chemical Research in Chinese Universities2001，17，1： | 4 |
| 10 | FRACTURAL PROCESS AND TOUGHENING MECHANISM OF LAMINATED CERAMIC COMPOSITES显示文摘基于多层的横梁的模型和假设材料微不同类,把压成薄片的陶器的 composites 的 3D fractural 特征与数字模拟被学习了。在三点的弯曲负担下面,击碎开始,结合,繁殖,调节离开在弱接口和期末考试,破裂被模仿了。声学的排放的空间分发和进化过程也在纸被介绍。模拟验证导致裂缝在那里膨胀并且吸收 fractural 精力的弱接口的主要机制。因此,力量的效果和坚韧上的材料的性质的纪律意义在这篇论文被讨论。 | Zhang Yafang Tang Chun'an Zhang Yongbin Liang Zhenzao | 2007 | Acta Mechanica Solida Sinica2007，20，2： | 3 |
| 11 | Characteristics of Long-term Nonprogressors and Viremia Controllers Infected with HIV-1 via Contaminated Blood Donations or Transfusions Conducted 20 Years Earlier显示文摘To characterize long‐term nonprogressors(LTNPs)and viremia controllers(VCs),infected with HIV‐1 through contaminated blood donation or transfusion between 1992 and 1996 in Henan,China.LTNPs and VCs were defined by CD4+T lymphocyte(CD4)count and viral load(VL).Of29,294 patients infected with HIV‐1 via contaminated blood donation or transfusion that had conducted for more than 20 years,92 were LTNPs/VCs.There were 70 LTNPs(0.24%),43 | LIU Jia FAN Pan Ying XUE Xiu Juan YAN Jiang Zhou SUN Guo Qing LIU Chun Hua TIAN Sui An LI Ning SUN Ding Yong ZHU Qian WANG Zhe | 2017 | Biomedical and Environmental Sciences2017，30，12： | 3 |
| 12 | Dynamic Mechanical Behavior of a Novel Polymeric Composite Damping Material显示文摘The dynamic mechanical behavior of a novel polymeric composite damping material has been investigated in this article. The composite consists of chlorinated polyethylene (CPE), N,N-dicyclohexyl-2-benzothiazolylsufenamide (DZ), 4,4′-thio-bis(3-methyl-6-tert-buthylphenol) (BPSR) and vapor-grown carbon fiber (VGCF). It is found that either the position or the intensity of damping peak can be controlled by changing the composition of CPE/DZ/BPSR composite. Within a certain composition region, damping peak maximum depends on CPE/DZ ratio, whereas damping peak position is controlled by BPSR content. Moreover, the improvement of storage modulus can be achieved by incorporation of VGCF. These results may imply that a damping material possessing both good damping properties and high strength can be designed and obtained. | Cheng ZHANG Jiang Feng SHENG Chun An MA | 2005 | Chinese Chemical Letters2005，16，11： | 3 |
| 13 | Metabolic Factors and Risk of Hepatocellular Carcinoma by Chronic Hepatitis B/C Infection: A Follow-up Study in Taiwan显示文摘 | Chi–Ling Chen Hwai–I. Yang Wei–Shiung Yang Chun–Jen Liu Pei–Jer Chen San–Lin You Li–Yu Wang Chien–An Sun Sheng–Nan Lu Ding–Shin Chen Chien–Jen Chen | 2008 | Gastroenterology2008，，1： | 3 |
| 14 | Changing characteristics of ultralow permeability reservoirs during waterflooding operations显示文摘The characteristics of ultralow permeability reservoirs changed after waterflooding.Thin-section analysis and scanning electron microscopy(SEM) of core samples from inspection wells indicated that calcite and barite were formed in ultralow permeability reservoirs during waterflooding operations.Some asphaltene precipitates on the surface of formation rock would influence the reservoir porosity,permeability,wettability,and electrical properties.In this paper,the changes of physical,electrical,and fluid properties of ultralow permeability reservoirs during waterflooding operations were analyzed.This provides important information to improve waterflooding performance in ultralow permeability reservoirs. | Gao Chunning An Xiaoping Zhu Shengju Wu Pingcang | 2013 | Petroleum Science2013，10，2： | 2 |
| 15 | Developments in Rail Transit:History and Future of Rail Transportation in Beijing | GUO Chun’an,Beijing Municipal Institute of City Planning and Design,Beijing,P.R.China.YAO Zhisheng,Beijing Municipal Institute of City Planning and Design,Beijing,P.R.China. QIAN Fang | 2009 | China City Planning Review2009，18，3： | 2 |
| 16 | Catalytic Hydrolysis of Borohydride for Fuel Cells显示文摘Borohydrides present interesting options for the electrochemical power generation acting either as hydrogen source or anodic fuel for direct borohydride fuel cells(DBFC).In this work,Mg-Ni composite synthesized by mechanically alloying method,used as the catalyst for the hydrolysis of borohydride,has been investigated.Co-doping treatment has been carried out for the purpose of improving the hydrolysis rate further.The as-prepared and Co-doped Mg-Ni composites with low cost showed high catalytic activity to the hydrolysis of borohydride for hydrogen generation.After Co-doping,the hydrogen generation rate was around 280 ml·g-1·min-1.Borohydride would be a promising hydrogen source for fuel cells. | WANG Lianbang ZHAN Xingyue YANG Zhenzhen MA Chun'an | 2011 | Chinese Journal of Chemical Engineering2011，19，4： | 2 |
| 17 | Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads显示文摘 | Tai‐Chung Tseng Chun‐Jen Liu Hung‐Chih Yang Tung‐Hung Su Chia‐Chi Wang Chi‐Ling Chen Cheng‐An Hsu Stephanie Fang‐Tzu Kuo Chen‐Hua Liu Pei‐Jer Chen Ding‐Shinn Chen Jia‐Horng Kao | 2012 | Hepatology2012，，： | 2 |
| 18 | Multi-Crack Coalesence in Rock-Like Material under Uniaxial and Biaxial Loading显示文摘 | Lin P. Wong R.H.C. Chau K.T. Tang Chun An | 2000 | 2000 (183)2000，，183： | 2 |
| 19 | Study on Inhibition Effects of Rare Earths on Superoxide Anion Radical by Using Pulse Radiolysis显示文摘The inhibition effect of rare earths on the production of ·O - 2 produced by radiolysis of aqueous sodium formate saturated with O 2 with high energy pulse electron beam was studied. The result indicates that rare earth nitrate obviously inhibits the production of ·O - 2 . The inhibition rate is between 28 6% and 92%. The inhibition effect increases with the increase of rare earth nitrates concentration. The distinguish dose effect relationship was observed. | WANG Chun xia 1, LIU Ya li 1, WANG Zi jian 1, PENG An 1, LI Feng mei 2, LIU Xiao guang 2 ( 1. State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco Environmental Science, Chinese Academy of Science, Beijing 100085, | 2000 | Journal of Rare Earths2000，18，3： | 2 |
| 20 | Influence of Polluted SY River on Child Growth and Sex Hormones显示文摘Objective To investigate the influence of the polluted SY River on children's growth and sex hormones,and provide scientific data for assessment of the polluted status of the SY River.Methods The study areas were selected randomly from the SY River Basin.Lead (Pb),mercury (Hg),arsenic (As),phthalates (DEP,DBP,DMP,DEHP),and bisphenol A (BPA) were measured both in the river water and in the drinking water.School children were selected by cluster sampling (n=154).Physical development indexes (height,weight,bust-circumference,and skinfold thickness) and sex hormones [testosterone (T) and estradiol (E2)] were measured for all the children.Results The contents of Pb and Hg exceeded Class V standards of surface water quality in each section of the river and other indicators exceeded Class III.Compared to the control area,the concentrations of Pb,Hg,As,BPA,DEP,and DBP in the drinking water were significantly higher than in the polluted area (P<0.05).Children from the control area had significantly lower E2 and T than children from the polluted area (P<0.05).Among anthropometric results,only skinfold thickness had statistically significant difference between the two groups (P<0.05),while the other indexes showed no significant differences between the two groups (P>0.05).Conclusion The drinking water has been polluted by the SY River and affected serum sex hormone levels of children living in the polluted area. | TANG Chun Yu LI An Qi GUAN Yong Bo LI Yan CHENG Xue Min LI Ping LI Shi Qun LUO Yi Xin HUANG Qi CHEN Hong Yang CUI Liu Xin | 2012 | Biomedical and Environmental Sciences2012，25，3： | 2 |
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