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| 1 | Treatment strategies using adefovir dipivoxil for individuals with lamivudine-resistant chronic hepatitis B显示文摘AIM:To investigate retrospectively the long-term efficacy of various treatment strategies using adefovir dipivoxil(adefovir) in patients with lamivudine-resistant chronic hepatitis B.METHODS:We included 154 consecutive patients in two treatment groups:the 'add-on' group(n = 79),in which adefovir was added to ongoing lamivudine treatment due to lamivudine resistance,and the 'switch/combination' group(n = 75),in which lamivudine was first switched to adefovir and then re-added later as needed.The 'switch/combination' group was then divided into two subgroups depending on whether participants followed(group A,n = 30) or violated(group B,n = 45) a proposed treatment strategy that determined whether to add lamivudine based on the serum hepatitis B virus(HBV) DNA levels(< 60 IU/mL or not) after 6 mo of treatment(roadmap concept).RESULTS:The cumulative probability of virologic response(HBV DNA < 60 IU/mL) was higher in group A than in the 'add-on' group and in group B(P < 0.001).In contrast,the cumulative probability of virologic breakthrough was lower in the 'add-on' group than in group B(P = 0.002).Furthermore,the risk of virologic breakthrough in the multivariate analysis was significantly lower in the 'add-on' group than in group A(hazard ratio = 0.096;95%CI,0.015-0.629;P = 0.015).CONCLUSION:The selective combination of adefovir with lamivudine based upon early treatment responses increased the odds of virologic breakthrough relative to the use of uniform combination therapy from the beginning of treatment. | Tae Jung Yun Jin Yong Jung Chang Ha Kim Soon Ho Um Hyonggin An Yeon Seok Seo Jin Dong Kim Hyung Joon Yim Bora Keum Yong Sik Kim Yoon Tae Jeen Hong Sik Lee Hoon Jai Chun Chang Duck Kim Ho Sang Ryu | 2012 | World Journal of Gastroenterology2012,18,47: | 19 |
| 2 | Predictive risk factors of perforation in gastric endoscopic submucosal dissection for early gastric cancer: a large, multicenter study显示文摘 | Min Kim Seong Woo Jeon Kwang Bum Cho Kyung Sik Park Eun Soo Kim Chang Keun Park Hyang Eun Seo Yun Jin Chung Joong Goo Kwon Jin Tae Jung Eun Young Kim Byeong Ik Jang Si Hyung Lee Kyeong Ok Kim Chang Hun Yang | 2013 | Surgical Endoscopy2013,,4: | 3 |
| 3 | Endoscopic submucosal dissection for early gastric cancer with undifferentiated histology: could we extend the criteria beyond?显示文摘 | Yi Young Kim Seong Woo Jeon JiYeon Kim Jung Chul Park Kwang Bum Cho Kyung Sik Park EunSoo Kim Yun Jin Chung Joong Goo Kwon Jin Tae Jung Eun Young Kim Kyeong Ok Kim ByungIk Jang Si Hyung Lee Chang Hun Yang | 2013 | Surgical Endoscopy2013,,12: | 3 |
| 4 | Analysis on sports and recreation activity-related eye injuries presenting to the Emergency Department显示文摘AIM:To investigate the incidence and general characteristics of sports-related eye injuries in patients visiting the Emergency Department. METHODS: A cross-sectional,multi-center,observational study.Patients with an injured eye who visited the Emergency Department at one of nine hospitals in Korea were enrolled.All data were prospectively collected between March and September 2010 using a questionnaire.Eye injuries that occurred during risky sports were examined by gender and age.Additionally,the rate of open globe injuries that occurred with and without protective eyewear was examined for each activity.Continuous variables were compared using Student's t-test and categorical variables were compared using Chi-square test.RESULTS: A total of 446 patients had sports-related eye injuries.Teenagers(10-19 years old) and young adults(20-29 years old) had the most eye injuries.Eye injuries accounted for 0.2% of Emergency Department patients.Baseball was the most common cause of sports-related eye injuries,followed by soccer and hiking.Protective gear was worn by 9.4% of all patients.Patients that were 30-39 years of age had the highest rate of protective gear use,followed by patients that were 40-49 years of age.The proportion of sports-related eye injuries that were open-globe injuries was highest for soccer and hiking.CONCLUSION: Although injuries were most common in patients below the age of 10 years,these patients had the lowest rate of protective eyewear use.Injuries in adults over 40 years of age most commonly occurred during hiking,but the rate of protective eyewear use was low.Young athletes should be educated on and provided with protective eyewear and policies protective gear use should be established.For older adults,eye protection should be encouraged,especially during hiking. | Sungbae Moon Hyun Wook Ryoo Jae Yun Ahn Jung Bae Park Kang Suk Seo Sang Do Shin Kyoung Jun Song Kang Hyun Lee In Sool Yoo Jin Seong Cho Hyun Ho Ryu Tae Oh Jeong Seok Ran Yeom Young Taek Kim Sung Ok Hong | 2016 | International Journal of Ophthalmology(English edition)2016,9,10: | 3 |
| 5 | The Effects of Aroma Acupuncture applied on Chronic Headache Patients显示文摘 | In Tae JUNG Su Yong KIM Doo Ik LEE Keon Sik KIM Jae Dong LEE Yun Ho LEE Do Young CHOI | 2005 | World Journal of Acupuncture-Moxibustion2005,15,3: | 2 |
| 6 | EMR versus gastrectomy for intramucosal gastric cancer: comparison of long-term outcomes显示文摘 | Kwi-Sook Choi Hwoon-Yong Jung Kee Don Choi Gin Hyug Lee Ho June Song Do Hoon Kim Jeong Hoon Lee Mi-Young Kim Byung Sik Kim Sung Tae Oh Jeong Hwan Yook Se Jin Jang Sung-Cheol Yun Seon Ok Kim Jin-Ho Kim | 2011 | Gastrointestinal Endoscopy2011,,5: | 2 |
| 7 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int J Cancer2012,,9: | 2 |
| 8 | Altered physiology of mesenchymal stem cells in the pathogenesis of adolescent idiopathic scoliosis显示文摘Adolescent idiopathic scoliosis is the most common spinal deformity during puberty,especially in females.It is characterized by aberrant skeletal growth and generalized reduced bone density,which is associated with impaired bone mineral metabolism.Despite recent progress in multidisciplinary research to support various hypotheses,the pathogenesis of Adolescent idiopathic scoliosis is still not clearly understood.One of the hypothesis is to study the role of mesenchymal stem cells due to its involvement in the above-mentioned bone metabolic abnormalities.In this review,we will summarize reported literatures on the role of mesenchymal stem cells,particularly in the pathogenesis of Adolescent idiopathic scoliosis.In addition,we will describe the research on mesenchymal stem cells of Adolescent idiopathic scoliosis performed using bioinformatics tools. | Dai Sik Ko Yun Hak Kim Tae Sik Goh Jung Sub Lee | 2020 | World Journal of Clinical Cases2020,8,11: | 2 |
| 9 | Diagnosis and staging of primary ovarian cancer: Correlation between PET/CT, Doppler US, and CT or MRI显示文摘 | Eun Ji Nam Mi Jin Yun Young Taik Oh Jae Wook Kim Jae Hoon Kim Sunghoon Kim Yong Wook Jung Sang Wun Kim Young Tae Kim | 2009 | Gynecologic Oncology2009,,: | 2 |
| 10 | Induction of indoleamine 2,3-dioxygenase expression via heme oxygenase-1-dependant pathway during murine dendritic cell maturation显示文摘 | In Duk Jung Jun Sik Lee Chang-Min Lee Kyung Tae Noh Yeong-Il Jeong Won Sun Park Sung Hak Chun Soo Kyung Jeong Jin Wook Park Kwang Hee Son Deok Rim Heo Min-Goo Lee Yong Kyoo Shin Han Wool Kim Cheol-Heui Yun Yeong-Min Park | 2010 | Biochemical Pharmacology2010,,: | 1 |
| 11 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int. J. Cancer2012,,9: | 1 |
| 12 | A Sesquiterpene Lactone, Costunolide, from Magnolia grandiflora Inhibits NF-κB by Targeting IκB Phosphorylation显示文摘 | Tae Koo Jeong-Hyung Lee Yun Park Young-Soo Hong Hang Kim Kyu-Won Kim Jung Lee | 2001 | Planta Med2001,,02: | 1 |
| 13 | Clinical value of tranexamic acid in unilateral and simultaneous bilateral TKAs under a contemporary blood-saving protocol: a randomized controlled trial显示文摘 | Tae Kyun Kim Chong Bum Chang Yeon Gwi Kang Eun Seok Seo Jung Ha Lee Joung Ho Yun Sun Hyung Lee | 2014 | Knee Surgery, Sports Traumatology, Arthroscopy2014,,8: | 1 |
| 14 | Application of metal hemoclips for closure of endoscopic mucosal resection–induced ulcers of the stomach to prevent delayed bleeding显示文摘 | Kee Don Choi Hwoon-Yong Jung Gin Hyug Lee Tae Hoon Oh Ji Yun Jo Ho June Song Seoung Soo Hong Jin-Ho Kim | 2008 | Surgical Endoscopy2008,,8: | 1 |
| 15 | Using geometric extrema for segment-tosegment characteristics comparison in online signature verification显示文摘 | Jaeyeon Lee Ho-Sub Yoon Jung Sob Byung Tae Chun Yun Koo Chung | 2004 | Pattern Recognition2004,37,1: | 1 |
| 16 | Comparison of endoscopic band ligation and endoclip closure of colonic perforation: T echnical feasibility and efficacy in an ex vivo pig model显示文摘 | Tae Hoon Lee Joung‐Ho Han Yoonho Jung Suck‐Ho Lee Dae Hoon Kim Ji Yun Shin Tae Soo Lee Myunghwan Kim Seok‐Hwa Choi Hyun Kim Seonmee Park Seijin Youn | 2014 | Digestive Endoscopy2014,,5: | 1 |
| 17 | Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice显示文摘 | Kyeong-Mi Choi Youn-Sun Lee Wonkyun Kim Seung Jung Kim Kyong-Oh Shin Ji-Yeon Yu Mi Kyeong Lee Yong-Moon Lee Jin Tae Hong Yeo-Pyo Yun Hwan-Soo Yoo | 2013 | The Journal of Nutritional Biochemistry2013,,: | 1 |
| 18 | Green Tea (-)-Epigallocatechin-3-Gallate Inhibits [beta]-Amyloid-Induced Cognitive Dysfunction through Modification of Secretase Activity via Inhibition of ERK and NF-[kappa]B Pathways in Mice1,2显示文摘 | Lee Jae Woong Lee Yong Kyoung Ban Jung Ok Ha Tae Youl Yun Yeo Pyo Han Sang Bae Oh Ki Wan Hong Jin Tae | 2009 | The Journal of Nutrition2009,,10: | 1 |
| 19 | Potential therapeutic effects of functionally active compounds isolated from garlic显示文摘 | Hyung-Mun Yun Jung Ok Ban Kyung-Ran Park Chong Kil Lee Heon-Sang Jeong Sang Bae Han Jin Tae Hong | 2013 | Pharmacology and Therapeutics2013,,: | 1 |
| 20 | Deleterious effects of silymarin on the expression of genes controlling endothelial nitric oxide synthase activity in carbon tetrachloride-treated rat livers显示文摘 | Yong Kyun Cho Jung Won Yun Jung Ho Park Hong Joo Kim Dong Il Park Chong Il Sohn Woo Kyu Jeon Byung Ik Kim Wook Jin Yong-Hyun Kwon Mi-Kyung Shin Tae Moo Yoo Ju-Hee Kang Chang-Shin Park | 2009 | Life Sciences2009,,7: | 1 |