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| 1 | Assessment of the Transmission Risk of Schistosomiasis after Flooding-North Poyang Lake,Jiangxi Province,China,2020显示文摘What is already known about this topic?Over 90%of Oncomelania snails,the only intermediate host of Schistosoma japonicum,are distributed in the middle and low reaches of Yangtze River.Flooding can extend the distribution of Oncomelania snails and hence accelerate the transmission of schistosomiasis.What is added by this report?Although the dispersal of Oncomelania snails was negligible in north Poyang Lake after flooding in 2020,2 samples of cattle feces with Schistosoma egg and 2 infected snails samples were indeed found.All four risk sites were distributed in Lushan County.Cattle feces were observed in the six out of seven field sites in Lushan County.What are the implications for public health practice?The present national control strategy focusing on control of infection source should be reinforced in Lushan and other schistosomiasis endemic areas.Overlaps of infected snails and cattle feces with Schistosoma egg were not observed,which called for intensive surveillance in Lushan County. | Shan Lv Fan Yang Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiao-nong Zhou | 2021 | China CDC weekly2021，3，5： | 5 |
| 2 | Rapid Assessment on Potential Risks of Schistosomiasis Transmission—7 PLADs,China,2019 and 2021显示文摘Summary What is already known about this topic?Oncomelania hupensis(O.hupensis)and livestock are main infection sources of schistosomiasis.The schistosome infected O.hupensis and livestock’s feces are important risk factors in the transmission of schistosomiasis.What is added by this report?The potential risks of schistosomiasis transmission remain prevalent,giving an early warning to local government with information on existing transmission risks.It is expected that the effectiveness and efficiency of schistosomiasis surveillance could be improved by conducting rapid risk assessment at the beginning of transmission season. | Junyi He Hongqing Zhu Ziping Bao Lijuan Zhang Yinlong Li Ting Feng Suying Guo Wangping Deng Can Wang Hui Dang Tiewu Jia Chao Lyu Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiaonong Zhou | 2021 | China CDC weekly2021，3，51： | 5 |
| 3 | Distribution Patterns of the Snail Intermediate Host of Schistosoma japonicum-China,2015−2019显示文摘What is already known about this topic?The endemic status of schistosomiasis appeared to continuously decrease in China from 2015 to 2019.The snail species Oncomelania hupensis is the only intermediate host involved in the transmission of Schistosoma japonicum,and this snail’s geographic distribution is strictly consistent with that of schistosomiasis.What is added by this report?The snail’s habitats did not decrease significantly in China from 2015 to 2019,and some habitats have been newly detected or recurrent in some regions.Snail habitats among nine counties in Hunan and Jiangxi covered nearly half of the areas with snails.What are the implications for public health practice?Considering the situation of snail distribution,strategies and measures on snail control should focus on key areas.In addition,study of the origin and causes of the newly-detected snail habitats and recurrent areas with snails needs to be strengthened,and comprehensive measures should be taken to prevent the spread of snails. | Lijuan Zhang Shan Lv Chunli Cao Jing Xu Shizhu Li | 2021 | China CDC weekly2021，3，5： | 2 |
| 4 | Social insights on the implementation of One Health in zoonosis prevention and control: a scoping review显示文摘Background:The One Health (OH) concept has been promoted widely around the globe. OH framework is expected to be applied as an integrated approach to support addressing zoonotic diseases as a significant global health issue and to improve the efficiency and effectiveness of zoonosis prevention and control. This review is intended to overview the social impact of the implementation of OH on zoonosis prevention and control.Methods:A scoping review of studies in the past 10 years was performed to overview the integration feature of OH in zoonosis prevention and control and the social impacts of OH. PubMed and Web of Science were searched for studies published in English between January 2011 and June 2021. The included studies were selected based on predefined criteria.Results:Thirty-two studies were included in this review, and most of them adopted qualitative and semi-qualitative methods. More than 50% of the studies focused on zoonosis prevention and control. Most studies were conducted in low- and middle-income countries in Africa and Asia. Applying OH approach in diseases control integrates policymakers, stakeholders, and academics from various backgrounds. The impact of OH on economic is estimated that it may alleviate the burden of diseases and poverty in the long term, even though more financial support might be needed at the initial stage of OH implementation. OH implementation considers social and ecological factors related to zoonosis transmission and provides comprehensive strategies to assess and address related risks in different communities according to regions and customs.Conclusions:Based on reviewed literature, although there seems to be a lack of guidelines for assessing and visualizing the outcomes of OH implementation, which may limit the large-scale adoption of it, evidence on the contributions of implementing OH concepts on zoonosis prevention and control indicates long-term benefits to society, including a better integration of politics, stakeholders and academics to improve their cooperation, a potential to address economic issues caused by zoonosis, and a comprehensive consideration on social determinants of health during zoonosis prevention and control. | Junyi He Zhaoyu Guo Pin Yang Chunli Cao Jing Xu Xiaonong Zhou Shizhu Li | 2022 | Infectious Diseases of Poverty2022，11，3： | 1 |
| 5 | Sandy Craig dean or pioglitazone combined with metformin first diagnosis of type 2 diabetes clinical observation 显示文摘 | Cao Chunli zhang jing hong-mei zhang | 2015 | Journal of Chinese medicine2015，17，10： | 1 |
| 6 | Circular dichroism spectroscopic studies on structures formed by telomeric DNA sequences in vitro显示文摘Telomere plays an important role in cellular processes, such as cell aging, death and carcinogenisis. Having special sequences, it can form quadrupiex structure in vitro. Circular dichroism (CD) spectroscopic studies show that TTAGGG, (TTAGGG)2 and (TTAGGG)4 can all form quadrupiex in vitro and exist mainly as parallel quadrupiex without metal ions. Both K+ and Na+ can stabilize the tetrameric structure and facilitate the forming of anti-parallel conformation. Furthermore, the conformations of quadrupiex can also be affected by sequence length, the nature and concentration of metal ions. | ZHANG Xiaoyan CAO Enhua SUN Xueguang BAI Chunli | 2000 | Chinese Science Bulletin2000，45，21： | 1 |
| 7 | 1 H NMR and multivariate data analysis of the relationship between the age and quality of duck meat显示文摘 | Chunli Liu Daodong Pan Yangfang Ye Jinxuan Cao | 2013 | Food Chemistry2013，，2： | 1 |
| 8 | Solubilization of substituted indole compounds byβ-cyclodextrin in water显示文摘 | Jiasheng Cao Chunli Zhao Liming Huang | 2000 | Chemosphere2000，，： | 1 |
| 9 | Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin 显示文摘 | Cao Dongsun Wang Zhigao Zhang Chunli | 2005 | Mol Cell Biol2005，25，： | 1 |
| 10 | Oral nano-antioxidants improve sleep by restoring intestinal barrier integrity and preventing systemic inflammation显示文摘Sleep deprivation(SD)is a severe public health threat that can cause systemic inflammation and nerve damage.Few effective and side-effect-free drugs are available to address SD.However,the bidirectional communications between the brain and gut provide new strategies for anti-SD therapeutics.Here we explored oral delivery of fullerene nano-antioxidants(FNAO)in the SD model to improve sleep by regulating abnormal intestinal barrier and systemic inflammation via the brain-gut axis.SD caused excessive reactive oxygen species(ROS)production and hyperactive inflammatory responses in the intestines of zebrafish and mouse models,leading to disturbed sleep patterns and reduced brain nerve activity.Of note,based on the property of the conjugatedπbond of the C_(60)structure to absorb unpaired electrons,oral FNAO efficiently reduced the excessive ROS in the intestines,maintained redox homeostasis and intestinal barrier integrity,and ameliorated intestinal and systemic inflammation,resulting in superior sleep improvement.Our findings suggest that maintaining intestinal homeostasis may be a promising avenue for SD-related nerve injury therapy. | Zhanfeng Wu Lei Liu Lei Li Xinran Cao Wang Jia Xiaodan Liao Zhongpu Zhao Hedong Qi Guoqiang Fan Huiqiang Lu Chunying Shu Mingming Zhen Chunru Wang Chunli Bai | 2023 | National Science Review2023，10，12： | 1 |
| 11 | Anti-catalytic and zincophilic layers integrated zinc anode towards efficient aqueous batteries for ultra-long cycling stability显示文摘Aqueous zinc-based battery is usually plagued by serious dendrites and side reactions including Zn corrosion and water decomposition on the anode.To address the drawbacks,constructing coating layers with high conductivity and anti-catalytic effects on hydrogen evolution reaction has been considered as an efficient strategy.Herein,cheap and abundant twodimensional(2D)conductive graphite(KS-6)coating layer with high electronic conductivity(~106 S·m^(−1))could directly form strong bonding with Zn foil due to high zincophilicity,which correspondingly protects Zn metal from liquid electrolyte to inhibit parasitic hydrogen evolution and guide uniform Zn electrodeposition during cycling.The KS-6 layer owns a profitable charge redistribution effect to endow Zn anode with a lower nucleation energy barrier and a more uniformly distributed electric field compared with bare Zn.Therefore,such integrated Zn anode exhibits low voltage hysteresis(~38 mV)and excellent cycling stability with dendrite-free behaviors(1 mA·cm^(−2)and 2 mAh·cm^(−2))over 2,000 h,far outperforming many reported Zn metal anodes in aqueous systems.Encouragingly,in light of the superior Zn@KS-6 anode,VNOx powders and Prussian blue analogs Mn_(2)Fe(CN)_(6)are applied as the cathode materials to assemble full batteries,which show remarkable cycling stabilities and high Coulombic efficiencies(CEs)over 200 cycles with capacity retention of 81.5%for VNOx//Zn@KS-6 battery and over 400 cycles with capacity retention of 94.6%for Mn_(2)Fe(CN)_(6)//Zn@KS-6 battery,respectively. | Chunli Wang Yuxing Gao Lianshan Sun Yuan Zhao Dongming Yin Hairui Wang Jingchao Cao Yong Cheng Limin Wang | 2022 | Nano Research2022，15，9： | 1 |
| 12 | Sequential extraction for arsenic species in dry seafood product and analysis with ICP-MS显示文摘 | CAO Xuan HAO Chunli WANG Geng | 2009 | Food Chem2009，113，2： | 1 |
| 13 | Sequential extraction combined with HPLC ICP - MS for As speciation in dry seafood products 显示文摘 | Xuan Cao Chunli Hao Geng Wang | 2009 | Food Chemistry2009，113，2： | 1 |
| 14 | Synthesis and properties of novel alkylbetaine zwitterionic gemini surfactants derived from cyanuric chloride 显示文摘 | XUE CHUNLI HU ZHIYONG CAO DUANLIN | 2011 | Colloids and Surface A : Physicoqhemical and Engineering Aspects2011，375，3： | 1 |
| 15 | Sentinel Surveillance of Schistosomiasis—China,2021显示文摘Introduction:This report analyzes the national surveillance data for schistosomiasis in 2021 to understand the current status and provide evidence for further policy actions to promote elimination.This analysis is in line with the National Surveillance Plan of Schistosomiasis,which was revised in 2020 to adapt to the new stage of moving towards elimination.Methods:Data from the 2021 national surveillance of schistosomiasis in humans,livestock,and snails were collected from 13 provincial-level administrative divisions(PLADs)and analyzed using descriptive epidemiological methodology.The antibody-positive rate and area of newly discovered and re-emergent snail habitats were calculated.Results:In 2021,a total of 31,661 local residents and 101,558 transient population were screened for antibodies using indirect hemagglutination assay(IHA).Of those who tested positive,745 local residents and 438 transient population underwent further parasitological examination,with only one stool-positive result in the transient population.Additionally,12,966 livestock were examined using the miracidia hatching test,with no positives detected.The total area of newly discovered and re-emergent snail habitats was 957,702 m^(2) and 4,381,617 m^(2),respectively.No infected snails were found using the microscopic dissection method,but six pooled snail samples were reported as positive using the loopmediated isothermal amplification method for detecting specific sequences of Schistosoma.japonicum,in Anhui and Jiangxi Provinces.Conclusions:The prevalence of schistosomiasis among humans and livestock was found to be low,however,a potential transmission risk was identified in certain areas.To reduce the risk of transmission,a comprehensive control strategy should be continued and new techniques should be implemented in the surveillance and early warning system. | Suying Guo Hui Dang Yinlong Li Lijuan Zhang Fan Yang Junyi He Chunli Cao Jing Xu Shizhu Li | 2023 | China CDC weekly2023，5，12： | 0 |
| 16 | Assemble four-arm DNA junctions into nanoweb显示文摘DNA is of structural polymorphism, which is useful in nanoarchitecture; especially, four-arm DNA junctions can be used to assemble nanowebs. The static four-arm DNA junctions were designed and synthesized. One-arm DNA and two-arm DNA came out simultaneously with the four-arm DNA junction’s formation. A new method, termed the two-step method, was proposed and the productivity of four-arm DNA junctions was increased. A nanoweb was assembled successfully, but it showed irregularity itself. It was not the same as we expected. We consider that it is a result from the flexibility of four-arm DNA junction. | ZHOU Chunqing TAN Zukun WANG Chen BAI Chunli CAO Enhua | 2001 | Chinese Science Bulletin2001，46，19： | 0 |
| 17 | Establishment of an indicator framework for global One Health Intrinsic Drivers index based on the grounded theory and fuzzy analytical hierarchy-entropy weight method显示文摘Background:One Health has become a global consensus to deal with complex health problems.However,the pro‑gress of One Health implementation in many countries is still relatively slow,and there is a lack of systematic evalua‑tion index.The purpose of this study was to establish an indicator framework for global One Health Intrinsic Drivers index(GOH-IDI)to evaluate human,animal and environmental health development process globally.Method:First,82 studies were deeply analyzed by a grounded theory(GT)method,including open coding,axial coding,and selective coding,to establish a three-level indicator framework,which was composed of three selective codes,19 axial codes,and 79 open codes.Then,through semi-structured interviews with 28 health-related experts,the indicators were further integrated and simplifed according to the inclusion criteria of the indicators.Finally,the fuzzy analytical hierarchy process combined with the entropy weight method was used to assign weights to the indi‑cators,thus,forming the evaluation indicator framework of human,animal and environmental health development process.Results:An indicator framework for GOH-IDI was formed consisting of three selective codes,15 axial codes and 61 open codes.There were six axial codes for“Human Health”,of which“Infectious Diseases”had the highest weight(19.76%)and“Injuries and Violence”had the lowest weight(11.72%).There were four axial codes for“Animal Health”,of which“Animal Epidemic Disease”had the highest weight(39.28%)and“Animal Nutritional Status”had the low‑est weight(11.59%).Five axial codes were set under“Environmental Health”,among which,“Air Quality and Climate Change”had the highest weight(22.63%)and“Hazardous Chemicals”had the lowest weight(17.82%).Conclusions:An indicator framework for GOH-IDI was established in this study.The framework were universal,balanced,and scientifc,which hopefully to be a tool for evaluation of the joint development of human,animal and environmental health in diferent regions globally. | Jiaxin Feng Zhaoyu Guo Lin Ai Jingshu Liu Xiaoxi Zhang Chunli Cao Jing Xu Shang Xia Xiao‑Nong Zhou Jin Chen Shizhu Li | 2022 | Infectious Diseases of Poverty2022，11，6： | 0 |
| 18 | Fullerene nanoparticles for the treatment of ulcerative colitis显示文摘Ulcerative colitis(UC) is a long-term,recurrent inflammatory bowel disease for which no effective cure is yet available in the clinical setting.Repairing the barrier dysfunction of the colon and reducing intestinal inflammation are considered key objectives to cure UC.Here we demonstrate a novel therapeutic strategy based on a C_(60) fullerene suspension(C_(60)FS) to treat dinitrobenzene sulfonic acid-induced UC in an animal model.C_(60)FS can repair the barrier dysfunction of UC and effectively promote the healing of ulcers;it also manifests better treatment effects compared with mesalazine enema.C_(60)FS can reduce the numbers of basophils in the blood of UC rats and mast cells in the colorectal tissue,thereby effectively alleviating inflammation.The expression of H1R,H4R,and VEGFR2 receptors in colorectal tissues is inhibited by C_(60)FS,and the levels of histamine and prostaglandin in the rat blood are reduced.This work presents a reliable strategy based on fullerene to cure UC and provides a novel guide for UC treatment. | Xiaodan Liao Zhongpu Zhao Hui Li Bo Wu Jiawei Huo Lei Li Xue Li Xinran Cao Min Xia Chunru Wang Chunli Bai | 2022 | Science China(Life Sciences)2022，65，6： | 0 |
| 19 | Application of mannose-modified fullerene immunomodulator selectively polarizes tumor-associated macrophages potentiating antitumor immunity显示文摘Polarization of tumor associated macrophages(TAMs)has been a promising therapeutic paradigm for tumor.However,how to achieve precise regulation of TAMs and high efficiency of tumor immunotherapy is still a huge challenge.Here,we report dicarboxy fullerene modified with mannose(DCFM)as an immunomodulator to selectively polarize TAMs and prominently boost anti-tumor immunity.The dicarboxy fullerene molecule was synthesized through the Prato reaction and further covalently bonded with mannose,obtaining the DCFM with well-defined structure.Due to the exist of mannose in DCFM,it could accurately recognize mannose receptor in TAMs.Our cellular experiment results showed that mannose modification could notably promote the uptake of DCFM by the immunosuppressive M2-type macrophages that effectively reprogrammed M2-type macrophages into anti-tumor M1-type macrophages,leading to enhance the phagocytosis of tumor cells by macrophages and inhibiting tumor cells migration.Subsequently,we observed that DCFM could significantly distribute into tumor tissues by in vivo fluorescence imaging.Importantly,DCFM exhibited a superior anti-tumor efficiency in the subcutaneous colorectal tumor model.In addition,it showed that DCFM precisely polarized TAMs into M1-type macrophages and actively increased the infiltration of cytotoxic T lymphocytes(CTLs),inducing profound tumor growth inhibition. | Haoyu Wang Lei Li Xinran Cao Mingming Zhen Chunru Wang Chunli Bai | 2023 | Nano Research2023，16，11： | 0 |
| 20 | Circular dichroism spectra of different structures formed by the oligonucleotides显示文摘Under different conditions, oligonucleotides can form several different DNA structures such as duplex, triplex and quadruplex. All these structures exhibit an obvious difference in their CD spectra. The common characteristic is that they show a negative band at 240 nm, while in the range of 260-300 nm, the spectra are different from each other. Many factors such as chain direction, sugar puckering mode, orientation of the glycosyl bond, base stacking and sequence can affect their conformation and then show diversity and complexity in their spectra. By studying and comparing these spectra, more information about their conformations can be obtained to help predict some new structures. Furthermore, the spectra can also provide a base to study their potential biological functions. | Xueguang Sun Enhua Cao Chunli Bai Yujian He Jingfen Qin | 1998 | Chinese Science Bulletin1998，43，17： | 0 |
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