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| 1 | Broad spectrum of interferon-related nephropathies-glomerulonephritis,systemic lupus erythematosus-like syndrome and thrombotic microangiopathy:A case report and review of literature显示文摘BACKGROUND Interferons(IFNs)are characterized by a wide range of biological effects,which justifies their potential therapeutic use in several pathologies,but also elicit a wide array of adverse effects in almost every organ system.Among them,renal involvement is probably one of the most complex to identify.CASE SUMMARY We describe four cases of kidney damage caused by different IFN formulations:IFN-β-related thrombotic microangiopathy,IFN-β-induced systemic lupus erythematosus,and two cases of membranous nephropathy secondary to pegylated-IFN-α2B.In each case,we carefully excluded any other possible cause of renal involvement.Once suspected as the casual relationship between drug and kidney damage,IFN treatment was immediately discontinued.In three cases,we observed a complete and persistent remission of clinical and laboratory abnormalities after IFN withdrawal,while the patient who developed thrombotic microangiopathy,despite IFN withdrawal and complement-inhibitor therapy with eculizumab,showed persistent severe renal failure requiring dialysis.CONCLUSION This case series highlights the causal relationship between IFN treatment and different types of renal involvement and enables us to delineate several peculiarities of this association. | Iacopo Gianassi Marco Allinovi Leonardo Caroti Lino Calogero Cirami | 2019 | World Journal of Nephrology2019，8，7： | 2 |
| 2 | Intravenous immunoglobulin Ther- apy of membranous nephropathy : efficacy and safety 显示文摘 | Palla R Cirami C Panichi V | 1991 | Clin Neph- ro11991，35，3： | 1 |
| 3 | The Effect of root stocks on the performance of Chardonnay from a nematode infected Barossa Valley vine yard 显示文摘 | Mccarthy M G Cirami R M | 1990 | American Journal of Enology and Viticulture1990，41，2： | 1 |
| 4 | Intravenous immunoglobulin therapy of membranous nephropathy: efficacy and safety 显示文摘 | Palla R Cirami C Paniehi V et el | 1991 | Clin Nephrol1991，35，3： | 1 |
| 5 | The effect of rootstocks on the performance of Chardonnay from a nematode infected Barossa Valley vineyard显示文摘 | Mccarthy MG Cirami RM | 1990 | American Journal of Enology and Viticulture1990，41，2： | 1 |
| 6 | Intravenous immunoglobulin therapy of membranous nephropathy: efficacy and safety 显示文摘 | Pallack R Cirami C Panichi V | 1991 | Clin Nephrol1991，35，1： | 1 |
| 7 | Effect of rootstock on must and wine composition and the sensory properties of Caber net sauvignon grown at Langhorne Creek, South Australia 显示文摘 | Gawel R Ewart A Cirami R | 2000 | Australian Journal of Grape and Wine Research2000，15，： | 1 |
| 8 | A new generation control sys- tem for astrophysical instruments显示文摘 | Cirami R Comari M Corte C | 2003 | Memorie della Societa Astro- nornica haliana Supplementi2003，3372，： | 1 |
| 9 | The effect of rootstocks on the performance of Chardonnay from a nematode infected Barossa Valley vineyard显示文摘 | Mccarthy M G Cirami R M | 1990 | American Journal of Enology and Viticulture1990，41，2： | 1 |
| 10 | Intravenous immunoglobu- lin therapy of membranous nephropathy: efficacy and safety 显示文摘 | Palla R Cirami C Panichi V | 1991 | Clin Nephrol1991，35，3： | 1 |
| 11 | Vine and fruit responses to supplementary irrigation and canopy management显示文摘 | McCarthy M G Cirami R M McCloud P | 1983 | South African Journal of Enology and Viticulture1983，4，2： | 1 |
| 12 | lntraveaous immunoglobulia therapy of membraaou nephropathy: efficacy and safety显示文摘 | Palla R Cirami C Panichi V | 1991 | Clia Nephrol1991，35，1： | 1 |
| 13 | The effect of rootstocks on the performance of Chardonnay from a nematode infected Barossa Valley vineyard显示文摘 | Mccarthy M G Cirami R M | 1990 | American Journal of Enology and Viticulture1990，41，2： | 1 |
| 14 | Intravenous immunoglobulin therapy of membranous nephropathy:efficacy and safety显示文摘 | Palla R Cirami C Panichi V | | 0，，03： | 1 |
| 15 | Minimal pruning effects on the performance of selections of four Vitis vinifera cultivars显示文摘 | MCCARTHY M G CIRAMI R M | 1990 | Vitis1990，29，： | 1 |
| 16 | Intravenous immunoglobulin Therapy of membranous nephropathy: efficacy and safety 显示文摘 | Palla R Cirami C Panichi V | 1991 | Clin Nephrol1991，35，3： | 1 |
| 17 | Multiple immune disorders in unrecognized celiac disease:a case report显示文摘We reported a female patient with unrecognized celiac disease and multiple extra intestinal manifestations, mainly related to a deranged immune function, including macroamilasemia, macrolipasemia, IgA nephropathy,thyroiditis, and anti-b2-glicoprotein-1 antibodies, that disappeared or improved after the implementation of a gluten-free diet. | Giorgio LaVilla Pietro Pantaleo Roberto Tarquini Lino Cirami Federico Perfetto Francesco Mancuso Giacomo Laffi | 2003 | World Journal of Gastroenterology2003，9，6： | 1 |
| 18 | The effect of rootstocks on the performance of Chardonnay from a nematodeinfected Barossa Valley vineyard显示文摘 | Cirami R M | 1990 | American Journal of Enology and Viticulture1990，41，2： | 1 |
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