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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | R- esponse of thymectomy: clinical and pathological characteristics among seronegative and seropositive myasthenia gravis patients 显示文摘 | Guillermo GR Tfillez Zenteno JF Weder Cisneros N | 2004 | Acta Neurol Scand2004，109，3： | 1 |
| 3 | Influence of the natural flake graph- ire particle size on the textural characteristic of exfoliated graphite used for heavy oil sorption显示文摘 | Vieira F Cisneros I Rosa N G | 2006 | Carbon2006，44，： | 1 |
| 4 | Bacterial urinary tract infection after solid organ transplantation in the RESITRA cohort显示文摘 | E. Vidal J. Torre‐Cisneros M. Blanes M. Montejo C. Cervera J.M. Aguado O. Len J. Carratalá E. Cordero G. Bou P. Mu?oz A. Ramos M. Gurguí N. Borrell J. Fortún | 2012 | Transpl Infect Dis2012，，6： | 1 |
| 5 | Quantitative pp65 antigenemia in the diagnosis of cytomegalovirus disease:prospective assessment in a cohort of solid organ transplant recipients显示文摘 | Bernabeu-Wittel M Pachón-Ib(a)(n)ez J Cisneros JM | 2005 | J Infect2005，51，3： | 1 |
| 6 | Receptor for advanced glycation end products is upregulated in optic neumpathy of Alzheimer's disease 显示文摘 | WANG M Y ROSS- CISNEROS F N AGGARWAL D | 2009 | Acta Neuro- patho12009，118，3： | 1 |
| 7 | Increased risk of severe hepatitis C virus recurrence after liver transplantation in patients with a T allele of IL28B rs12979860显示文摘 | Cisneros E Ba(n)os I Citores MJ | | 0，，： | 1 |
| 8 | Risk factors for the development of bronchopulmonary dysplasia: acase-controlstudy显示文摘 | Hernandez-Ronquillo L Tellez-Zenteno JF Weder Cisneros N | 2004 | Arch Med Res2004，35，6： | 1 |
| 9 | Evaluation of the Use of BioGlue? in the Treatment of High Anal Fistulas: Preliminary Results of a Pilot Study显示文摘 | Fernando Portilla M.D. Ricardo Rada M.D. Eva León M.D. Nieves Cisneros M.D. Victor Hugo Maldonado M.D. Eduardo Espinosa M.D | 2007 | Diseases of the Colon & Rectum2007，，2： | 1 |
| 10 | Creation of novel inter- specific-interploid Hylocereus hybrids (Cactaceae) via embryo rescue显示文摘 | CISNEROS A GARCIA R B TEL-ZUR N | 2013 | Euphytica2013，189，3： | 1 |
| 11 | Synthesis, characterization,DNA binding study and biological activity against leishmania mexicana of BF4显示文摘 | Maribel N Efren J Cisneros F | 2003 | Inorg Biochem2003，97，4： | 1 |
| 12 | Bacteremia due to Acinetobacter baumannii: epidemiology, clinical and prognostic feat u res显示文摘 | Cisneros J M Reyes M J Pach 6 n J | 1996 | Olin Infect Dis1996，22，6： | 1 |
| 13 | Risk factors for the development of bronchopulmonary dysplasia: a case - control study 显示文摘 | Hernandez - Ronquillo L Tellez - Zenteno JF Weder- Cisneros N | 2004 | Arch Med Res2004，35，6： | 1 |
| 14 | Embryo rescue and plant regeneration follow interspecifie crosses in the genus Hylocereus (Cactaceae) 显示文摘 | CISNEROS A TEL-ZUR N | 2010 | Euphytiea2010，174，： | 1 |
| 15 | Ovule morphology and seed development in three Hylocereus species (Cactaceae) 显示文摘 | CISNEROS A BENEGA GARCIA R TEL-ZUR N | 2011 | Flora2011，206，： | 1 |
| 16 | Effect of temperature on the tensile properties of an as-cast aluminum alloy A319显示文摘 | E. Rincón H.F. López M.M. Cisneros H. Mancha M.A. Cisneros | 2006 | Materials Science & Engineering A2006，，： | 1 |
| 17 | Bacteremia due to Acinetobacter baumannii:epidemiology,clinical findings,and prognostic features显示文摘 | Reyes M J Pachón J | 1996 | Clin Infect Dis1996，22，6： | 1 |
| 18 | Synthesis,characterization,DNA binding study and biological activity against Leishmania mexicana of BF4显示文摘 | MARIBEL N EFREN J CISNEROS F | 2003 | J Inorg Biochem2003，97，4： | 1 |
| 19 | Creation of novel interspecific-interploid Hylocereus hybrids (Cactaceae) via embryo rescue显示文摘 | Cisneros A Garcia R B Tel-Zur N | 2013 | Euphytica2013，189，： | 1 |
| 20 | Genomic analysis in three Hylocereus species and their progeny: evidence for introgressive hybridization and gene flow显示文摘 | Cisneros A Tel-Zur N | 2013 | Euphytica2013，194，： | 1 |
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