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16篇 您的检索式:作者名="Ciudin"
    题名 作者 年代 出处 被引量
1Neurodegeneration:An early event of diabetic retinopathy显示文摘Diabetic retinopathy(DR) has been classically considered to be a microcirculatory disease of the retina caused by the deleterious metabolic effects of hyperglycemia per se and the metabolic pathways triggered by hyperglycemia.However,retinal neurodegeneration is already present before any microcirculatory abnormalities can be detected in ophthalmoscopic examination.In other words,retinal neurodegeneration is an early event in the pathogenesis of DR which predates and participates in the microcirculatory abnormalities that occur in DR.Therefore,the study of the mechanisms that lead to neurodegeneration will be essential to identify new therapeutic targets in the early stages of DR.Elevated levels of glutamate and the overexpression of the renin-angiotensin-system play an essential role in the neurodegenerative process that occurs in diabetic retina.Among neuroprotective factors,pigment epithelial derived factor,somatostatin and erythropoietin seem to be the most relevant and these will be considered in this review.Nevertheless,it should be noted that the balance between neurotoxic and neuroprotective factors rather than levels of neurotoxic factors alone will determine the presence or absence of retinal neurodegeneration in the diabetic eye.New strategies,based on either the delivery of neuroprotective agents or the blockade of neurotoxic factors,are currently being tested in experimental models and in clinical pilot studies.Whether these novel therapies will eventually supplement or prevent the need for laser photocoagulation or vitrectomy awaits the results of additional clinical research.Marta Villarroel Andreea Ciudin Cristina Hernández Rafael Simó 2010World Journal of Diabetes2010,1,2:41
2Effect of glycemic control on nocturnal arterial oxygen saturation: A case‐control study in type 2 diabetic patients 血糖控制对夜间动脉血氧饱和度的影响:一项2型糖尿病患者的病例对照研究显示文摘Albert Lecube Andreea Ciudin Gabriel Sampol Silvia Valladares Cristina Hernández Rafael Simó 2015Journal of Diabetes2015,,:2
3Air cystoscopy is superior to water cystoscopy for the diagnosis of active hematuria显示文摘Ciudin A Diaconu MG Gosalbez D 2013J Urol2013,190,6:1
4Prevalence and risk factors accounting for true silent myocardial ischemia: a pilot case-control study comparing type 2 diabetic with non-diabetic con- trol subjects显示文摘Hernandez C Candell-Riera J Ciudin A 2011Cardiovasc Diabetol2011,10,:1
5Isolated Langerhans Cell Histiocytosis of the Thyroid in an Adult Female: One-Year Followup显示文摘Vilallonga R Ciudin A Fort JM 2011International Journal of Endocrinology2011,1,89:1
6The tachyarrhythmic car-diomyopathy-a rare entity in childhood显示文摘Ghiorghiu I Ciudin R Serban M 2004Intern Med2004,42,3:1
7The tachyarrhythmie cardiomyopathy-a rare entity in childhood显示文摘Ghiorghiu I Ciudin R Serban M 2004Intern Meal2004,42,3:1
8Validation of Randall's plaque theory using unen- hanced abdominal computed tomography显示文摘Ciudin A Luque Galvez M P Salvador Izquierdo R 2013Urology2013,81,2:1
9The tachyarrhythmic cardiomyopathy-a rare entity in childhood 显示文摘Ghiorghiu I Ciudin R Serban M 2004Intern Med2004,42,3:1
10Effect of atorvastatin on lipoprotein(a) and interleukin-10: a randomized placebo-controlled trial显示文摘Hernandez C Francisco G Ciudin A 2011Diabetes Metab2011,37,2:1
11Comparative study of three different DNA fingerprint techniques for molecular typing of shigella flexneri strains isolated in romania 显示文摘Surdeanu M Ciudin L Pencu E 2003European Journal of Epidemiology2003,18,7:1
12Neurodegeneration : An early event of diabetic retJnopatby显示文摘Villarroel M Ciudin A Hem6ndez C 2010World J Diabetes2010,1,2:1
13Update on cardiovascular safety of PPARgamma agonists and relevance to medicinal chemistry and clinical pharmacology显示文摘Ciudin A Hernandez C Simo R 2012Curr Top Med Chem2012,12,6:1
14Prevalence and risk factors accounting for true silent myocardial ischemia: a pilot case- control study comparing type 2 diabetic with non-diabetic control subjects显示文摘Hernandez C Candell-Riera J Ciudin A 2011Cardiovascular diabetology2011,10,1:1
15Transposition of iliae vessels in implantation of right living donor kidneys显示文摘Ciudin A Musquera M Huguet J 2012Transplant Proe2012,44,:1
16The tachyarrhythmic cardiomyopathy--a rare entity in childhood 显示文摘Ghiorghiu I Ciudin R Serban M Popescu BA Ginghini C 2004Rom J Intern Med2004,42,3:1
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