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| 1 | 预期寿命估计对脊柱转移瘤手术选择与预后预测的临床意义显示文摘背景与目的:目前,临床上对脊柱转移瘤患者是否采取手术治疗以及如何选择手术仍然存在较大的争议。预期寿命的估计是手术选择的决定因素之一。本研究旨在评价Tokuhashi和Tomita评分系统这两种常用的预期寿命估计方法对硬膜外脊柱转移瘤患者手术选择与预后预测的临床价值。方法:对2001年1月至2004年4月丹麦奥胡斯大学医院脊柱外科中心收治的169例硬膜外脊柱转移瘤入组患者,术前用Tokuhashi与Tomita评分系统进行评分以及估计预期寿命,并结合Tomita脊柱肿瘤分型,选择实施手术分级治疗。术后6个月、12个月以及24个月分别进行前瞻性随访观察。对在预期寿命为“3个月内死亡”、“6个月内死亡”以及“12个月内死亡”的患者通过Tokuhashi与Tomita评分系统绘制受试者作业特征曲线(receiveroperatingcharacteristiccurves,ROC曲线),比较两个评分系统对预期寿命估计的准确性。同时采用Kaplan-Meier生存曲线分析法,计算Tokuhashi和Tomita评分系统各分数段患者术后的实际平均生存时间。结果:预期寿命分别为“3个月内死亡”、“6个月内死亡”以及“12个月内死亡”的病例ROC曲线分析显示,Tomita评分系统与Tokuhashi评分系统之间的差异均无显著性(各组P值分别为0.16、0.47与0.38)。Kaplan-Meier生存曲线分析显示,Tomita评分系统在4~7分之间对预后估计过高,Tokuhashi评分系统在0~8分之间对预后估计过低。结论:Tokuhashi和Tomita评分系统均可成功地预测脊柱转移瘤患者术后预后的情况。Tokuhashi评分系统可较为准确地预测生存期较短的患者,从而避免对这类患者做不必要的大手术。 | 邹学农 Anders Grejs 李海声 Kristian Hφy Ebbe S Hansen Cody Bünger | 2006 | 癌症2006，25，11： | 18 |
| 2 | Plankton patchiness in highfrequency internal waves 显示文摘 | Lennert Cody C E Franks P J S | 1999 | Marine Ecology Progress Series1999，186，： | 1 |
| 3 | Extending the operational window during Gulf of Mexico Loop currents显示文摘 | MITCHELL S REEL M CODY R | 2006 | World Oil2006，，7： | 1 |
| 4 | P-selectin blockade following fluid - percussion injury : behavioral and immu- nochemical sequelae 显示文摘 | GRADY M S CODY R F Jr MARIS D O | 1999 | J Neurotrauma1999，16，1： | 1 |
| 5 | An outbreak of Eschefichia coli O157:H7 infection from tmpasteurized commercial apple juice显示文摘 | CODY S H GLYNN M K FARRAR J A | 1999 | Ann Intern Med1999，130，： | 1 |
| 6 | Determination of chemical-structural changes in vitrinite accompanying luminescence alteration using C-NEXAFS analysis 显示文摘 | Cody G D Ade H Wirick S | 1998 | Organic Geochemistry1998，28，78： | 1 |
| 7 | Integrating a Digital Library and a Traditional Library:Librarians and Scientists Collaborating for Sustainability显示文摘 | Benedetti S Cody S A Hanerfeld A | 2007 | Technical Services Quarterly2007，，3： | 1 |
| 8 | Characteristics and outcomes of sentinel node-positive breast cancer patients after total mastectomy without axillary-specific treatment显示文摘 | Milgrom S Cody H Tan L | 2012 | Ann Surg Oncol2012，19，12： | 1 |
| 9 | Confocal imaging of ionised calcium in living plant cells显示文摘 | WILLIAMS D A CODY S H GEHRING C A | 1990 | Cell Calcium1990，11，： | 1 |
| 10 | Development of an optical biosensor using gold nanoparticles and quantum dots for the detection of Porcine Reproductive and Respiratory Syndrome Virus显示文摘 | Cody S R Schomme S Hoehn D | 2008 | Sens Actuator B-Chem2008，134，2： | 1 |
| 11 | Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity显示文摘 | Yury I. Miller Soo-Ho Choi Philipp Wiesner Longhou Fang Richard Harkewicz Karsten Hartvigsen Agnès Boullier Ayelet Gonen Cody J. Diehl Xuchu Que Erica Montano Peter X. Shaw Sotirios Tsimikas Christoph J. Binder Joseph L. Witztum | 2011 | Circulation Research2011，，2： | 1 |
| 12 | Silver surfers:Training and evaluating Internet use among older adult learners显示文摘 | Cody M.J Dunn D Hoppin S Wendt P | | 0，，： | 1 |
| 13 | Barramundi as an indicator species for environmental monitoring in North Queensland, Australia: laboratory versus field studies显示文摘 | Codi S Humphrey C Klumpp D | 2004 | Environ Toxicol Chem2004，23，11： | 1 |
| 14 | Change is good: Variations in common biological mecha- nisms inthe epsilonproteobacterial genera Campylobacter and Helicobacter 显示文摘 | GILBREATH J J CODY W L MERRELL D S | 2011 | Microbiology and Molecular Biology Review2011，75，1： | 1 |
| 15 | Determination of chemical-structural changes in vitrinite accompanying luminescence alteration using C-NEXAFS analysis显示文摘 | Cody G D Ade H Wirick S | 1998 | Organic Geochemistry1998，28，78： | 1 |
| 16 | Maternal vitamin D deficiency,refractory neonatal hypocalcaemia,and nutritional rickets显示文摘 | Swifi P Cody D | 2005 | Arch Dis Child2005，90，4： | 1 |
| 17 | Hospital mortality, length of stay, and preventable complications among critically ill pa- tients before and after tele-icu reengineering of critical care processes显示文摘 | Lilly CM Cody S Zhao H | 2011 | JAMA2011，305，21： | 1 |
| 18 | Characteristics and outcomes of sentinel node-positive breast cancer patients after total mas- tectomy without axillary-specific treatment 显示文摘 | Milgrom S Cody H Tan L | 2012 | Ann Surg On- col2012，19，12： | 1 |
| 19 | 显示文摘 | Abeies B Beers D S Cody G D | 1962 | Phys Rev1962，125，1： | 1 |
| 20 | Characteristics and outcomes of sentinel node-positive breast cancer patients after total mastectomy without axillary-specific treatment 显示文摘 | Milgrom S Cody H Tan L | 2012 | Ann Surg Onco12012，19，12： | 1 |
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