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2篇 您的检索式：作者名="Cong Junzi"

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		题名	作者	年代	出处	被引量
	1	Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy显示文摘Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal scle rosis.There is no effective treatment for cognitive impairment.Medial septum cholinergic neurons have been reported to be a potential target for controlling epileptic seizures in tempo ral lobe epile psy.However,their role in the cognitive impairment of temporal lobe epilepsy remains unclear.In this study,we found that patients with temporal lobe epile psy with hippocampal sclerosis had a low memory quotient and severe impairment in verbal memory,but had no impairment in nonverbal memory.The cognitive impairment was slightly correlated with reduced medial septum volume and medial septum-hippocampus tra cts measured by diffusion tensor imaging.In a mouse model of chronic temporal lobe epilepsy induced by kainic acid,the number of medial septum choline rgic neurons was reduced and acetylcholine release was reduced in the hippocampus.Furthermore,selective apoptosis of medial septum cholinergic neurons mimicked the cognitive deficits in epileptic mice,and activation of medial septum cholinergic neurons enhanced hippocampal acetylcholine release and restored cognitive function in both kainic acid-and kindling-induced epile psy models.These res ults suggest that activation of medial septum cholinergic neurons reduces cognitive deficits in temporal lobe epilepsy by increasing acetylcholine release via projections to the hippocampus.	Junzi Chen Yu Wang Cong Chen Qingyang Zhang Shuang Wang Yi Wang Jiajia Fang Ying Wang	2023	Neural Regeneration Research2023，18，11：	1
	2	Synthesis of thieno pyrazine-based and 2,1,3-benzothia-diazole-based donor-acceptor copolymers and their application in photovoltaic devices 显示文摘	Zhou Erjun Cong Junzi Yamakawa Shimpei	2010	Macromolecules2010，43，6：	1

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