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| 1 | Liver transplantation in patients with incidental hepatocellular carcinoma/cholangiocarcinoma and intrahepatic cholangiocarcinoma: a single-center experience显示文摘BACKGROUND: Reports of liver transplantation(LT) in patients with mixed hepatocellular carcinoma/cholangiocarcinoma(HCC/CC) and intrahepatic cholangiocarcinoma(ICC) are modest and have been mostly retrospective after pathological categorization in the setting of presumed HCC. Some studies suggest that patients undergoing LT with small and unifocal ICC or mixed HCC/CC can achieve about 40%-60% 5-year post-transplant survival. The study aimed to report our experience in patients undergoing LT with explant pathology revealing HCC/CC and ICC.METHODS: From a prospectively maintained database, we performed cohort analysis. We identified 13 patients who underwent LT with explant pathology revealing HCC/CC or ICC. RESULTS: The observed recurrence rate post-LT was 31%(4/13) and overall survival was 85%, 51%, and 51% at 1, 3 and 5 years, respectively. Disease-free survival was 68%, 51%, and 41% at 1, 3 and 5 years, respectively. In our cohort, four patients would have qualified for exception points based on updated HCC Organ Procurement and Transplantation Network imaging guidelines. CONCLUSIONS: Lesions which lack complete imaging characteristics of HCC may warrant pre-LT biopsy to fully elucidate their pathology. Identified patients with early HCC/CC or ICC may benefit from LT if unresectable. Additionally, incorporating adjunctive perioperative therapies such as in the case of patients undergoing LT with hilar cholangiocarcinoma may improve outcomes but this warrants further investigation. | Mohammed Elshamy Naftali Presser Abdulrahman Y Hammad Daniel J Firl Christopher Coppa John Fung Federico N Aucejo | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，3： | 6 |
| 2 | Vaccination with Autologous Tumor-derived Heat-Shock Protein Gp96 after liver resection for metastatic Colorectal Cancer显示文摘 | Mazzaferro V Coppa J Carraba MG | 2003 | Clin Cancer Res2003，15，9： | 1 |
| 3 | Liver transplantation for small hepatocellular carcinoma in cirrhosis:analysis of our experience显示文摘 | Regalia E Coppa J Pulvirenti A | 2001 | Transplant Proc2001，33，12： | 1 |
| 4 | Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer显示文摘 | Mazzaferro V Coppa J Carrabba MG | 2003 | Clin Cancer Res2003，9，9： | 1 |
| 5 | Neuroendocrine tumors metastatic to the liver: how to select patients for liver transplantation?显示文摘 | Mazzaferro V Pulvirenti A Coppa J C | 2007 | J Hepatol2007，47，： | 1 |
| 6 | Pigeons memory for empty time intervals marked by visual or auditory stimuli显示文摘 | Santi A Ross L Coppa R Coyle J | 1999 | Animal Learning & Behavior1999，87，： | 1 |
| 7 | Neuroendoerine tumors metastalie to lhe liver: how to seleel palienls for liver transplan- talion?显示文摘 | Mazzaferro V Pulvirenti A Coppa J | 2007 | J Hepalol2007，47，4： | 1 |
| 8 | Neuroendocrine tumors metastatic to the liver: how to select patients for liver transplanta- tion? 显示文摘 | Mazzaferro V Pulvirenti A Coppa J | 2007 | J Hepatol2007，47，4： | 1 |
| 9 | Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer显示文摘 | Mazzaferro V Coppa J Carrabba M G | 2003 | Clin Cancer Res2003，9，9： | 1 |
| 10 | The Timing of Auditory and Visual Signals by Pigeons:Differential Sensitivity to Intertrial Interval Duration显示文摘 | Santi A Coyle J Coppa R Ross L | 1998 | Learning and Motivation1998，29，： | 1 |
| 11 | Liver transplantation for small hepatocellular carcinoma in cirrhosis: analysis of our experience显示文摘 | Regalia E Coppa J pulvirenti A | 2001 | Transpl Proc2001，33，： | 1 |
| 12 | Liver transplantation for small hepatecellular carcinoma in cirrhosis: analysis of our experience显示文摘 | Regalia E Coppa J Pulvirenti A | 2001 | Transplantation Proceedings2001，33，： | 1 |
| 13 | Natural killer and NK-Like T-cell activation in eoloreetal carcinoma patients treated withautolo- gous tumor-derived heat shock protein 96 显示文摘 | Pilla L Squarcina P Coppa J | 2005 | Cancer Res2005，65，9： | 1 |
| 14 | Neuroendocrine tumors met- astatie to the liver: how to select patients for liver transplanta- tion? 显示文摘 | Mazzaferro V Pulvirenti A Coppa J | 2007 | J Hepatol2007，47，4： | 1 |
| 15 | Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer 显示文摘 | MAZZAFERRO V COPPA J CARRABBA MG | 2003 | Clin Cancer Res2003，9，9： | 1 |
| 16 | Vaccination with autologous tumor-derived heat-shock protein Gp96 after liver resection for metastatic colorectal cancer显示文摘 | Mazzaferro V Coppa J Carrabba M G | 2003 | Clinical Cancer Research2003，9，9： | 1 |
| 17 | Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer显示文摘 | Mazzaferro V Coppa J Carrabba MG | 2003 | Cancer Res2003，9，9： | 1 |
| 18 | Natural killer and NK-like T-cell activation in colorectal carcinoma patients treated with autologous tumor-derived heat shock protein 96显示文摘 | Pilla L Squarcina P Coppa J | 2005 | Cancer Res2005，6，9： | 1 |
| 19 | Vaccination with autologous tumor-derived heat-shock protein gp96 after liver resection for metastatic colorectal cancer显示文摘 | MAZZAFERRO V COPPA J CARRABBA M G | 2003 | Clin Cancer Res2003，9，9： | 1 |
| 20 | Natural killer and NK -like T- cell activation in colorectal carcinoma patients treated with autologous tumor- derived heat shock protein 96 显示文摘 | Pilla L Squarcina P Coppa J | 2005 | Cancer Res2005，65，9： | 1 |
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