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您的检索式：作者名="Cormac McCarthy"
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| 1 | 治疗学 控制不佳的哮喘治疗显示文摘一名35岁男性,既往诊断轻度哮喘,他告知家庭医生,在过去3个月中他间断在夜间咳醒或因气短而憋醒。他是一名厨师,现在已经感到难以完成轮班工作。长期以来,他每天吸入2次倍氯米松200μg,由于持续发作的症状,他询问是否需要改变治疗。控制不佳的哮喘或中度哮喘是指患者每天有哮喘症状。 | Orla O′Carroll Cormac McCarthy Marcus W Butler 王颖(译) 施焕中(校) | 2022 | 英国医学杂志中文版2022，25，1： | 0 |
| 2 | Inhaled hypertonic saline for cystic fibrosis: Reviewing the potential evidence for modulation of neutrophil signalling and function显示文摘Cystic fibrosis(CF) is a multisystem disorder with significantly shortened life expectancy. The major cause of mortality and morbidity is lung disease with increasing pulmonary exacerbations and decline in lung function predicting significantly poorer outcomes. The pathogenesis of lung disease in CF is characterised in part by decreased airway surface liquid volume and subsequent failure of normal mucociliary clearance. This leads to accumulation of viscous mucus in the CF airway, providing an ideal environment for bacterial pathogens to grow and colonise, propagating airway inflammation in CF. The use of nebulised hypertonic saline(HTS) treatments has been shown to improve mucus clearance in CF and impact positively upon exacerbations, quality of life, and lung function. Several mechanisms of HTS likely improve outcome, resulting in clinically relevant enhancement in disease parameters related to increase in mucociliary clearance. There is increasing evidence to suggest that HTS is also beneficial through its anti-inflammatory properties and its ability to reduce bacterial activity and biofilm formation. This review will first describe the use of HTS in treatment of CF focusing on its efficacy and tolerability. The emphasis will then change to the potential benefits of aerosolized HTS for the attenuation of receptor mediated neutrophil functions, including down-regulation of oxidative burst activity, adhesion molecule expression, and the suppression of neutrophil degranulation of proteolytic enzymes. | Emer P Reeves Cormac McCarthy Oliver J McElvaney Maya Sakthi N Vijayan Michelle M White Danielle M Dunlea Kerstin Pohl Noreen Lacey Noel G McElvaney | 2015 | World Journal of Critical Care Medicine2015，4，3： | 0 |
| 3 | 征途(英文)显示文摘在这部小说里,作者将西方世界塑造成一个后启示时代(人类经历了大灾难后的世界,post-apocalyptic one)。没有法制的地带常常滋生暴力(engender violence),但在这里一场核子大屠杀(a nuclear holocaust)几乎将一切化为灰烬,只剩下几个可怜的灵魂等待着悲惨的命运。主要人物是一对父子,讲述了他们如何抗争命运的不幸,努力避免'坏家伙'的生存技巧,做着人性最后的挣扎。虽然是恐怖小说,但温情描写仍不乏见于字里行间,细节刻画的微妙作用从以下这段文字可见一斑。 | Cormac McCarthy | 2008 | 海外英语2008，0，3： | 0 |
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