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| 1 | Influence of Genista Tinctoria L or Methylparaben on Subchronic Toxicity of Bisphenol A in Rats显示文摘Objective To evaluate the influence of an extract of Genista tinctoria L. herba(GT) or methylparaben(MP) on histopathological changes and 2 biomarkers of oxidative stress in rats subchronicly exposed to bisphenol A(BPA). Methods Adult female Wistar rats were orally exposed for 90 d to BPA(50 mg/kg), BPA+GT(35 mg isoflavones/kg) or BPA+MP(250 mg/kg). Plasma and tissue samples were taken from liver, kidney, thyroid, uterus, ovary, and mammary gland after 30, 60, and 90 d of exposure respectively. Lipid peroxidation and in vivo hydroxyl radical production were evaluated by histological analysis along with malondialdehyde and 2,3-dihydroxybenzoic acid detection. Results The severity of histopathological changes in liver and kidneys was lower after GT treatment than after BPA or BPA+MP treatment. A minimal thyroid receptor antagonist effect was only observed after BPA+MP treatment. The abnormal folliculogenesis increased in a time-dependent manner, and the number of corpus luteum decreased. No significant histological alterations were found in the uterus. The mammary gland displayed specific estrogen stimulation changes at all periods. Both MP and GT revealed antioxidant properties reducing lipid peroxidation and BPA-induced hydroxyl radical generation. Conclusion GT L. extract ameliorates the toxic effects of BPA and is proved to have antioxidant potential and antitoxic effect. MP has antioxidant properties, but has either no effect or exacerbates the BPA-induced histopathological changes. | Daniela-Saveta POPA Pompei BOLFA Bela KISS Laurian VLASE Ramona PLTINEAN Anca POP Cornel CTOI Gianina CRISAN Felicia LOGHIN | 2014 | Biomedical and Environmental Sciences2014，27，2： | 2 |
| 2 | Behavior-based Neuro-fuzzy Controller for Mobile Robot Navigation 显示文摘 | RUSU P PETRIU E M WHALEN T E CORNELL A SPOELDER H J W | 2003 | IEEE Transactions on Instrumentation and Measurement2003，52，4： | 1 |
| 3 | Bipolar hemiarthroplasty for fracture of the femoral neck 显示文摘 | Goldhill V B Lyden J P Cornell C N | 1991 | J Orthop Trauma1991，5，3： | 1 |
| 4 | Biosorption of Dyes Using Dead Macro Fungi: Effect of Dye Structure, Ionic Strength and pH显示文摘 | MAURYA N S MITrAL M K CORNEL P | 2006 | Bioresource Technology2006，97，3： | 1 |
| 5 | An authentic 3' noncoding region is necessary for efficient Poliovirus replication显示文摘 | Brown D M Cornell C T Tran G P | 2005 | J Virol2005，79，11： | 1 |
| 6 | A second gener-ation force field for the simulation of proteins, nucleic acids, and or- ganic molecules 显示文摘 | CORNELL W D CIEPLAK P BAYLY C I | 1995 | American Chemical Society1995，117，19： | 1 |
| 7 | Earthquakes, records, and nonlinear responses 显示文摘 | Shome N Cornell C A Bazzurro P | 1998 | Earthquake Spectra1998，14，3： | 1 |
| 8 | A Second Generation Force Field for the Simulation of Proteins,Nucleic Acids,and Organic Molecules显示文摘 | Cieplak P Bayly C I | 1995 | J Am Chem Soc1995，117，19： | 1 |
| 9 | Terminal distributary channels and delta front architecture of river-dominated delta systems显示文摘 | Cornel O Janak P B | 2006 | Journal of Sedimentary Research2006，76，： | 1 |
| 10 | Effect of silicate species on the transformation of ferrihydrite into goethite and hematite in alkaline media显示文摘 | Cornell R M Giovanoli R Schindler P W | 1987 | Clays Clay M in1987，35，1： | 1 |
| 11 | On disaggregation of seismic hazard显示文摘 | Bazzurro P Cornell C A | 1999 | Bulletin of the Seismological Society of America1999，89，2： | 1 |
| 12 | Structural performance assessment under near-source pulse-like ground motions using advanced ground motion intensity measures 显示文摘 | Tothong P Cornell C A | 2008 | Earthquake Engineering and Structural Dynamics2008，37，7： | 1 |
| 13 | Structural performance assessment under near-source pulse-like ground motions using advanced ground motion intensity measures显示文摘 | Tothong P Cornell C A | 2008 | Earthquake Engineering & Structural Dynamic2008，37，： | 1 |
| 14 | Phosphorus recovery from wastewater: needs, technologies and costs 显示文摘 | Cornel P Schaum C | 2009 | Water Science and Technology2009，59，6： | 1 |
| 15 | Applications of low loss amorphous metals in motors and transformers 显示文摘 | Johnson L A Cornell E P Bailey D J | 1981 | IEEE Transac-tions on Power Apparatus and Systems1981，101，7： | 1 |
| 16 | Application of low loss amorphous metals in motors and transformers 显示文摘 | JOHNSON L A CORNELL E P BAILEY D J | 1982 | IEEE Transactions on Power Apparatus and Systems1982，101，7： | 1 |
| 17 | A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges-the resp model显示文摘 | BAYLY C I CIEPLAK P CORNELL W D | 1993 | Journal of Physical Chemistry1993，97，10： | 1 |
| 18 | A second generation force field for the simulation of proteins, nucleic acids, and organic molecules显示文摘 | CORNELL W D CIEPLAK P BAYLY C I | 1995 | J Am Chem Soc1995，117，： | 1 |
| 19 | Impact of SBAR on nurse shift reports and staff rounding显示文摘 | Cornell P Gervis M T Yates L | 2014 | Med Surg Nurs2014，23，5： | 1 |
| 20 | Diffusion of humic acidin dilute aqueous solution显示文摘 | Cornel P K Summers R S Roberts P V | 1985 | Journal of Colloid and Interface Science1985，110，1： | 1 |
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