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| 1 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 2 | Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation显示文摘BACKGROUND The impact of perioperative blood transfusion on short-and long-term outcomes in pediatric living donor liver transplantation(PLDLT)must still be ascertained,mainly among young children.Clinical and surgical postoperative complications related to perioperative blood transfusion are well described up to three months after adult liver transplantation.AIM To determine whether transfusion is associated with early and late postoperative complications and mortality in small patients undergoing PLDLT.METHODS We evaluated the effects of perioperative transfusion on postoperative complications in recipients up to 20 kg of body weight,submitted to PLDLT.A total of 240 patients were retrospectively allocated into two groups according to postoperative complications:Minor complications(n=109)and major complications(n=131).Multiple logistic regression analysis identified the volume of perioperative packed red blood cells(RBC)transfusion as the only independent risk factor for major postoperative complications.The receiver operating characteristic curve was drawn to identify the optimal volume of the perioperative RBC transfusion related to the presence of major postoperative complications,defining a cutoff point of 27.5 mL/kg.Subsequently,patients were reallocated to a low-volume transfusion group(LTr;n=103,RBC≤27.5 mL/kg)and a high-volume transfusion group(HTr;n=137,RBC>27.5 mL/kg)so that the outcome could be analyzed.RESULTS High-volume transfusion was associated with an increased number of major complications and mortality during hospitalization up to a 10-year follow-up period.During a short-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and bleeding complications,with a decrease in rejection complications compared to the LTr.Over a long-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and minor neoplastic complications,with a decrease in rejection complications.Additionally,Cox hazard regression found that high-volume RBC transfusion increased the mortality risk by 3.031-fold compared to low-volume transfusion.The Kaplan-Meier survival curves of the studied groups were compared using log-rank tests and the analysis showed significantly decreased graft survival,but with no impact in patient survival related to major complications.On the other hand,there was a significant decrease in both graft and patient survival,with high-volume RBC transfusion.CONCLUSION Transfusion of RBC volume higher than 27.5 mL/kg during the perioperative period is associated with a significant increase in short-and long-term postoperative morbidity and mortality after PLDLT. | Karina Gordon Estela Regina Ramos Figueira Joel Avancini Rocha-Filho Luiz Antonio Mondadori Eduardo Henrique Giroud Joaquim Joao Seda-Neto Eduardo Antunes da Fonseca Renata Pereira Sustovitch Pugliese Agustin Moscoso Vintimilla Jose Otavio Costa Auler Jr Maria Jose Carvalho Carmona Luiz Augusto Carneiro D'Alburquerque | 2021 | World Journal of Gastroenterology2021，27，12： | 6 |
| 3 | Comparison of intravitreal versus posterior sub - Tenon' s capsule injection of triameinolone aeetonide for diffuse diabetic macular edema显示文摘 | Cardillo JA Melo LA Jr Costa RA | 2005 | Ophthahnology2005，112，9： | 1 |
| 4 | Acute myocardial infarction associated to myocardial bridging显示文摘 | Esteves V Barbosa RR Costa JR | 2010 | Rev Bras Cardiol Invasiva2010，18，4： | 1 |
| 5 | Differential increase of mitochondrial matrix volume by sevoflurane in isolated cardiac mitochondria显示文摘 | Riess ML Costa AD Carlson R Jr | 2008 | Anesth Analg2008，106，： | 1 |
| 6 | An apparent in verse relationship between serum cholesterol and cancer mortality in puerto Rito显示文摘 | Carcia-Pal men MR Shoilie PD Costas R Jr | 1981 | Am J Epide moil1981，114，： | 1 |
| 7 | Kinetic modelling of steam gasification of various woody biomass chars:Influence of inorganic elements显示文摘 | Dupont Capucine Nocquet Timothée José Augusto Da Costa Jr | 2011 | Bioresource Technology2011，102，20： | 1 |
| 8 | Increment in hCG in the48- hperiodpriortotreatment: a new variable predictive of therapeuticsuccess treatment of eetopic pregnancy with methotrexate 显示文摘 | Da Costa Soares R Elito J Jr Camano L | 2008 | ArchGynecol Ob- stet2008，278，4： | 1 |
| 9 | Intraoperative without conjunctival and Tenen's capsule touch in primary trabeculectomy显示文摘 | Susanna R Jr Costa VP Malta RF | 2001 | Ophthalmology2001，108，6： | 1 |
| 10 | Validation of the five - factor model of personality across instruments and observers 显示文摘 | MCCRAE R R COSTA P T JR | 1987 | J Pers Soc Psychol1987，52，1： | 1 |
| 11 | Influence of the thickness of mineral trioxide aggregate on sealing ability of root - end fillings in vitro显示文摘 | Valois CR Costa ED Jr | 2004 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2004，97，1： | 1 |
| 12 | Endometrial thickness as an orienting factor for the medical treatment of unruptured tubal pregnancy显示文摘 | Da Costa Soares R Elito J Jr Han KK | 2004 | Acta Obstet Gynaecol Scand2004，83，3： | 1 |
| 13 | Evaluation of small intestine bacterial overgrowth in patients with func- tional dyspepsia through H2 breath test显示文摘 | Costa MB Azeredo IL Jr Marciano RD | 2012 | Arq Gastroenterol2012，49，4： | 1 |
| 14 | Increment in beta-hCG in the 48-h period prior to treatment:a new variable predictive of therapeutic success in the treatment of ectopic pregnancy with methotrexate显示文摘 | da Costa Soares R Elito J Jr Camano L | 2008 | Arch Gynecol Obstet2008，278，4： | 1 |
| 15 | Film growth and relationship between microstructure and mechanical properties of a-C: H: F films deposited by PECVD显示文摘 | Maia da Costa M E H Jacobsohn L G | 2001 | Diamond and Related Materials2001，10，： | 1 |
| 16 | Updating norman's adequate taxonomy' : Intelligence and personality dimensions in natural language and in questionnaires显示文摘 | MCCRAE R R COSTA JR P T | 1985 | J Personality Soc Psyehol1985，，49： | 1 |
| 17 | Different substance P receptors are found on mucosal epithelial cells and submucous neurons of the guinea-pig small intestine 显示文摘 | Furness JB Costa M | 1985 | Naunyn Schmiedebergs Arch Pharmacol1985，329，4： | 1 |
| 18 | Personality and metabolic syn- drome 显示文摘 | Sutin AR Costa Jr PT Uda M | 2010 | Age2010，32，4： | 1 |
| 19 | Localization lengths of ultrathin disordered gold and silver nanowires显示文摘 | Costa A T jr Muniz R B Hong J S | 2004 | Europhysies Letters2004，67，2： | 1 |
| 20 | Amorphous SiC coatings for WC cutting tools 显示文摘 | COSTA A K CAMARGO JR S S | 2003 | Surface and Coatings Technology2003，，1： | 1 |
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