|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | H pylori status and angiogenesis factors in human gastric carcinoma显示文摘AIM: To investigate H pylori expression in gastric cancer patients in relation to primary tumor angiogenic markers, such as microvessel density (MVD), thymidine phospho- rylase (TP), vascular endothelial growth factor receptor-1 (VEGF-R1), p53 and circulating VEGF levels. METHODS: Angiogenic markers were analyzed immu- nohistochemically in 56 primary gastric cancers. H pylori cytotoxin (vacA) and the cytotoxin-associated gene (cagA) amplification were evaluated using PCR assay. Serum H pylori IgG antibodies and serum/plasma circulating VEGF levels were detected in 39 and 38 patients by ELI- SA, respectively. RESULTS: A total of 69% of patients were positive for circulating IgG antibodies against H pylori. cagA-positive H pylori strains were found in 41% of gastric patients. vacA was found in 50% of patients; s1 strains were more highly expressed among vacA-positive patients. The presence of the s1 strain was signifi cantly associ- ated with cagA (P = 0.0001). MVD was signifi cantly cor- related with both tumor VEGF expression (r = 0.361, P = 0.009) and serum VEGF levels (r = -0.347, P = 0.041).Conversely, neither VEGF-R1 expression nor MVD was related to p53 expression. However, H pylori was not related to any angiogenic markers except for the plasma VEGF level (P = 0.026). CONCLUSION: H pylori antigen is related to higher plasma VEGF levels, but not to angiogenic character- istics. It can be hypothesized that the toxic effects of H pylori on angiogenesis occurs in early preclinical dis- ease phase or in long-lasting aggressive infections, but only when high H pylori IgG levels are persistent. | Anita Mangia Annalisa Chiriatti Girolamo Ranieri Ines Abbate Maria Coviello Giovanni Simone Francesco Alfredo Zito Severino Montemurro Antonello Rucci Alfredo Di Leo Stefania Tommasi Pasquale Berloco Jian Ming Xu Angelo Paradiso | 2006 | World Journal of Gastroenterology2006，12，34： | 5 |
| 2 | Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina显示文摘 | Libster R Bugna J Coviello S | 2010 | N Engl J Med2010，362，1： | 1 |
| 3 | Blind source separation and beamforming: Algebraic technique analysis 显示文摘 | Coviello C M Sibul L H | 2004 | IEEE Transactions on Aerospace and Electronic systems2004，40，1： | 1 |
| 4 | Effects of Graded Doses of Testosterone on Erythropoiesis in Healthy Young and Older Men显示文摘 | Andrea D. Coviello Beth Kaplan Kishore M. Lakshman Tai Chen Atam B. Singh Shalender Bhasin | 2008 | The Journal of Clinical Endocrinology & Metabolism2008，，3： | 1 |
| 5 | The Network Dynamics of International New Ventures 显示文摘 | Coviello Nicole | 2006 | Journal of International Business Studies2006，37，5： | 1 |
| 6 | Internationalization of Service SMEs: An integrated perspective from the engineering consulting sector显示文摘 | COVIELLO NE MARTIN A-M | 1999 | Journal of International Marketing1999，，： | 1 |
| 7 | Intensive insulin therapy in critically ill patients显示文摘 | Hirsch IB Coviello A Mazuski J | 2002 | N Engl J Med2002，346，： | 1 |
| 8 | Vascular endothelial growth factor assessment in different blood fractions of gastrointestinal cancer patients and healthy controls显示文摘 | Ranieri G Coviello M Chiriatti A | 2004 | Oncol Rep2004，11，2： | 1 |
| 9 | Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance 显示文摘 | Coviello AD Legro RS DunaifA | 2006 | J Clin Endocrinol Metab2006，91，2： | 1 |
| 10 | Lactobacillus sepsis and probiotic therapy in newborns: two new cases and literature review显示文摘 | Dani C Coviello CC Corsini II | 2016 | AJP Rep2016，6，1： | 1 |
| 11 | A mutant tropomypsin that causes hypertrophic cardiomyopathy is expressed in vivo and associated with an increased calcium sensitivity显示文摘 | Bottinelli R Coviello DA Redwood CS | 1998 | Cite Res1998，82，1： | 1 |
| 12 | Adolescent girls with polyeystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resis- tance显示文摘 | Coviello AD Legro RS Dunaif A | 2006 | J Clin Endocrinol Metab2006，91，2： | 1 |
| 13 | Vascular endothelial growth factor concentrations in the plasma-activated platelets rich (P-APR) of healthy controls and colorectal cancer patients显示文摘 | Ranieri G Coviello M Patruno R | 2004 | Oncol Rep2004，12，4： | 1 |
| 14 | Contemporary marketing practices of consumer and business-to-business firms: How different are they显示文摘 | Coviello N.E R.J.Brodie | | 0，，05： | 1 |
| 15 | Pediatric hospitalizations associated with 2009 pandemic influenza A(H1N1) in Argentina显示文摘 | Libster R Bugna J Coviello S | 2010 | N Engl J Med2010，362，1： | 1 |
| 16 | Adolescent girls withpolycystic ovary syndrome have an increased risk of the metabolicsyndrome associated with increasing androgen levels independentof obesity and insulin resistance显示文摘 | Coviello AD Legro RS Dunaif A | 2006 | J Clin Endocrinol MeTab2006，91，49： | 1 |
| 17 | MMP-2,MMP-9,VEGF and CA153 in breast cancer显示文摘 | Quaranta M Daniele A Coviello M | | 0，，05： | 1 |
| 18 | Internationalisation: Conceptualisingan Entrepreneurial Process of Behavior in Time 显示文摘 | JONES M V ’ COVIELLO N E | 2005 | Journalof International Business Studies2005，，36： | 1 |
| 19 | MMP-2 andMMP-9,VEGF and CA153 in breast cancer显示文摘 | Quaranta M Daniele A Coviello M | 2007 | Anti- cancer Res2007，27，5： | 1 |
| 20 | prognostic role of heart rate variability in patients with ST-segment elevation acute myocardial infarction treated by primary angioplasty 显示文摘 | Coviello I Pinnacchio G Laurito M | 2013 | Cardiology2013，124，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员