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77篇 您的检索式:作者名="Coward C"
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1睾酮缺乏症的诊断和治疗显示文摘近些年来,随着睾酮缺乏症(TD)发病率的上升、新药的不断开发、以及商业推广的深入,睾酮替代疗法(TST)的临床应用显著增多。然而,关于睾酮缺乏症的诊断标准以及TST的应用和监测,仍然不是很明确。此种现象主要源于睾酮的多重作用靶点。在人体内,睾酮参与了很多生理过程的调节,同时睾酮的表达水平也受很多疾病及药物的影响。因此,睾酮缺乏症的临床症状和体征具有多样性和非特异性,也就增加了睾酮缺乏症的诊断难度,尤其在老年人群中。临床上,关于血清睾酮水平的检测也存在争议,不同实验室之间存在一定的差异,因此也很难界定睾酮水平的诊断标准。很多医学专业组织试图制定睾酮缺乏症的诊断指南,但彼此间很难达成统一。另外,临床使用的睾酮制剂也层出不穷,相应的TST治疗方案也像TD的诊断标准一样不断更新和变化。临床上,随着TST的不断推进,专科医师必须不断更新对于TD和HTST的了解和治疗及应用。本文旨在阐述TD的最新概念及其诊断和治疗的新进展。James A McBride Culley C Carson Robert M Coward 2015Asian Journal of Andrology2015,17,2:5
2Genistein, daidzein and their β - glycoside conjugates: antitumor isoflavones in soy- bean foods from American and Asian diets 显示文摘Coward L Banes N C Setchell K D R 1993J Agric Food Chem1993,41,:1
3Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis 显示文摘COWARD W R WATTS K FEGHALI-BOSTWICK C A 2010Mol Cell Biol2010,30,12:1
4Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channelsin human pain states显示文摘Coward K Plumpton C Facer P 2000Pain2000,85,12:1
5Phytoestrogens: where are we now显示文摘Bingham SA Atkinson C Liggins J Bluck L Coward A 1998Br J Nutr1998,79,:1
6Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis显示文摘COWARD W R WATTS K FEGHALI-BOSTWICK C A 2010Mol Cell Biol2010,30,12:1
7Proliferation rates of HepG2 cells encapsulated in alginate are increased in a microgravity envi- ronment compared with static cultures 显示文摘Coward SM Selden C Mantalaris A 2005Artif Organs2005,29,2:1
8Genistein, Daidzein and Theier Fl-Glucosidase Conjugates:Antitumor Isofla-vones in Soybean Foods from American and Asian Diets 显示文摘Coward L Barnes N C Setchell K D R 1993Agric Food Chem1993,41,:1
9Epidemiology of paediatric renal stone disease in the UK 显示文摘Coward RJ Peters C J Duffy PG 2003Arch Dis Child2003,88,11:1
10显示文摘Coward L Barnes N C Setchell K D 1993Agric Food Chem1993,41,:1
11Inhibition of spawningand associated suppression of sex steroid levels during con- finement in the substrate-spawning Tilapia zillii显示文摘Coward K Bromage N R Little D C 1998J Fish Biol1998,52,1:1
12Genistein, daidzein, and their fl-glycoside conju gates: antitumer isof lavones in soybean foods from American and Asian diets显示文摘COWARD L BARNES N C SETCHELL K D R 1993J A gric Food Chem1993,,41:1
13Genistein,daidzein,and their β-glycoside conjugates:antitumer isoflavones in soybean foods from American and Asian diets显示文摘 Barnes N C Setchell K D R 1993J Agric Food Chem1993,41,:1
14O-antigen repeat number in Salmonella enterica serovar Enteritidis is important for egg contamination, colonisation of the chicken reproductive tract and survival in egg albumen显示文摘Coward C Salt L Cogan T 2013FEMS Microbiology Letters2013,343,2:1
15Genistein,daidzein and theier β-glucosidase conjugates:antitumor isoflavones in soybean foods from American and Asian diets显示文摘Coward L Barnes N C Setchell K D R 1993J Agric Food Chem1993,41,:1
16A photonic inte- grated-optic RF phase shifter for phased array antennabeam-forming applications 显示文摘Coward J F Yee T K Ohalfant C H 1993Journal of Lightwave Technology1993,,12:1
17Genistein,daidzein,and their glycoside conjugates:Antitumor isoflavones in soybean foods from American and Asian diets显示文摘Coward L Barnes N C Setchell K D R Barnes S 1993J Agric Food Chem1993,31,:1
18Genistein,daidzein and theier β-glucosidase conjugates:antitumor isoflavones in soybean foods from American and Asian diets显示文摘Coward L Barnes N C Setchell K D R 1993Journal of Agricultural and Food Chemistry1993,41,:1
19Comparison of pharmaeokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaaeetate 显示文摘JIA L COWARD L KERSTNER - WOOD C D 2008Cancer Chemoth Pharm2008,61,1:1
20Comparative dietary intake and sources of phylloquinone (vitamin K1) among British adults in 1986-7 and 2000-1 显示文摘Thane C W Bolton-Smith C Coward W A 2006Br J Nutr2006,96,6:1
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