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| 1 | 卒中相关性肺炎的诊断卒中肺炎共识小组的推荐意见显示文摘背景和目的下呼吸道感染常并发于卒中并对转归造成不利影响。对于并发于卒中的下呼吸道感染性疾病,目前尚无公认的专业术语或诊断金标准,这导致临床诊疗和研究受到影响。本共识旨在提出急性卒中并发下呼吸道感染的标准化术语和可操作性诊断标准。方法对多个文献数据库进行系统检索,经过证据回顾和2轮讨论,最后于2014年9月在英国曼彻斯特召开共识会议,经75%以上共识小组成员达成一致意见后形成共识。结果达成的共识如下:(1)推荐使用卒中相关性肺炎(stroke-associated pneumonia, SAP )作为卒中发病后7 d内发生的下呼吸道感染性疾病的专业术语。(2)提议对 SAP 使用经过改良的美国疾病控制预防中心(Centers for Disease Control and Prevention, CDC)诊断标准:①很可能的 SAP:符合 CDC 诊断标准,但复查或动态监测胸部 X 片仍缺乏典型改变;②确诊的 SAP:符合 CDC 诊断标准,且胸部 X 片有典型改变。(3)关于白细胞计数或 C反应蛋白在 SAP 诊断中的作用证据有限。(4)其他生物学标记物(如降钙素原)的证据不足。结论提议根据 CDC 诊断标准对 SAP 的术语和诊断制定可操作性的共识标准,需要在卒中患者中进行前瞻性研究来确定其信度、效度以及对医生行为(包括抗生素选择)和临床转归的影响。 | Craig J. Smith Amit K Kishore Andy Vail Angel Chamorro Javier Garau Stephen J. Hopkins Mario Di Napoli Lalit Kalra Peter Langhorne Joan Montaner Christine Roffe Anthony G. Rudd Pippa J. TyrreU Diederik van de Peek Mark Woodhead Andreas Meisel 范琳琳 宿英英 | 2016 | 国际脑血管病杂志2016，24，2： | 17 |
| 2 | Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke:an updated systematic review显示文摘The optimal dose of recombinant tissue plasminogen activator(rtPA)for acute ischaemic stroke(AIS)remains controversial,especially in Asian countries.We aimed to update the evidence regarding the use of low-dose versus standard-dose rtPA.We performed a systematic literature search across MEDLINE,Embase,Cochrane Central Register of Controlled Trials(CENTRAL),PsycINFO and Cumulative Index to Nursing and Allied Health Literature(CINAHL)from inception to 22 August 2016 to identify all related studies.The outcomes were death or disability(defined by modified Rankin Scale 2-6),death,and symptomatic intracerebral haemorrhage(sICH).Where possible,data were pooled for meta-analysis with ORs and corresponding 95% CIs by means of random-effects or fixed-effects meta-analysis.We included 26 observational studies and 1 randomised controlled trial with a total of 23210 patients.Variable doses of rtPA were used for thrombolysis of AIS in Asia.Meta-analysis shows that low-dose rtPA was not associated with increased risk of death or disability(OR 1.13,95% CI 0.95 to 1.33),or death(OR 0.86,95% CI 0.74 to 1.01),or decreased risk of sICH(OR 1.06,95% CI 0.65 to 1.72).The results remained consistent when sensitivity analyses were performed including only low-dose and standard-dose rtPA or only Asian studies.Our review shows small difference between the outcomes or the risk profile in the studies using low-dose and/or standard-dose rtPA for AIS.Low-dose rtPA was not associated with lower risk of death or disability,death alone,or sICH. | Xia Wang Shoujiang You Shoichiro Sato Jie Yang Cheryl Carcel Danni Zheng Sohei Yoshimura Craig S Anderson Else Charlotte Sandset Thompson Robinson John Chalmers Vijay K Sharma | 2018 | Stroke & Vascular Neurology2018，3，1： | 10 |
| 3 | Atmospheric argon contamination of ocean island basalt olivine phenocrysts 显示文摘 | Faryley K A Craig H | 1994 | Geochim Cosmochim Acta1994，58，： | 2 |
| 4 | Binary mixing of enriched and undegasses (primitive?) mantle components (He,Sr,Nd,Pb) in Samoan lavas 显示文摘 | Farley K A Natland J H Craig H | 1992 | Earth Planet Sci Lett1992，111，： | 2 |
| 5 | Reflective Tomography Images from Range-resolved Laser Radar Measurements 显示文摘 | PARKER J K CRAIG E B KLICK D L el al | 1988 | Applied Optics1988，27，13： | 1 |
| 6 | A high- density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease 显示文摘 | Coon K D Myers A J Craig D W | 2007 | J Clin Psychiatry2007，68，4： | 1 |
| 7 | Design optimization of a single-strand continuous caster tundish using residence time distribution data显示文摘 | Craig K J de Kock D J Makgata K W | 2001 | ISIJ International2001，41，10： | 1 |
| 8 | Crack growth in HY80 and HY130 steels by corrosion fatigue显示文摘 | Congleton J Craig I H Denton B K | 1979 | Material Science1979，13，7： | 1 |
| 9 | Life-cycle reliability characteristics of minimum structures显示文摘 | R G Bea A Brandtzaeg M J K Craig | 1998 | Journal of Offshore mechanics and Arctic Engineering1998，120，： | 1 |
| 10 | Life-cycle reliability characteristics of minimum structures显示文摘 | Bea R G Brandtzaeg A Craig M J K | 1998 | Journal of Offshore Mechanics and Arctic Engineering1998，120，： | 1 |
| 11 | Absence of Fer protein tyrosine kinase exacerbates endotoxin induced intestinal epithelial barrier dysfunction in vivo显示文摘 | Qi W Ebbert K Craig A | | 0，，： | 1 |
| 12 | Morphologic changes in the peritoneal membrane of patients with renal disease 显示文摘 | Williams JD Craig K J Topley N | 2002 | J Am Soc Nephrol2002，13，2： | 1 |
| 13 | The promise of hematopoietic stem cell transplantation for autoimmune diseases 显示文摘 | Burr R K TraynorA E Craig R | 2003 | Bone Marrow Transplant2003，31，7： | 1 |
| 14 | Apolipoprotein E ε4 allele influences aggressive behaviour in Alzheimer's disease显示文摘 | Craig D Hart DJ McCool K | 2004 | J Neurol Neurosurg Psychiatry2004，75，9： | 1 |
| 15 | Dietary intake and arsenic methy- lation in a US Population 显示文摘 | Craig S Kenichi C Dave K | 2005 | Environ Health Perspect2005，113，： | 1 |
| 16 | Im- pacts of increased fire frequency and aridity on euealypt forest structure,biomass and composition in southwest Australia显示文摘 | Burak K Pekin Matthias M Boer Craig Macfarlane | 2009 | Forest Ecology and Management2009，258，： | 1 |
| 17 | Intracranial internal carotid artery stenosis 显示文摘 | Craig DR Meguro K Watridge C | 1982 | Stroke1982，13，6： | 1 |
| 18 | Thermosensory activation of insular cortex显示文摘 | Craig A D Chen K Bandy D | 2000 | Nat Neurosci2000，3，2： | 1 |
| 19 | Facing others in pain: the effects of empathy 显示文摘 | Goubert L Craig K Vervoort T | 2005 | Pain2005，118，： | 1 |
| 20 | PAR1-mediated RhoA activation facilitates CCL2-induced chemotaxis in PC-3 cells显示文摘 | Loberg RD Tantivejkul K Craig M et | 2007 | J Cell Biochem2007，101，5： | 1 |
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