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| 1 | Red pigment production by Penicillium purpurogenum GH2 is influenced by pH and temperature显示文摘The combined effects of pH and temperature on red pigment production and fungal morphology were evaluated in a submerged culture of Penicillium purpurogenum GH2, using Czapek-Dox media with D-xylose as a carbon source. An experimental design with a factorial fix was used: three pH values (5, 7, and 9) and two temperature levels (24 and 34 °C) were evaluated. The highest production of red pigment (2.46 g/L) was reached with a pH value of 5 and a temperature of 24 °C. Biomass and red pigment production were not directly associated. This study demon- strates that P. purpurogenum GH2 produces a pigment of potential interest to the food industry. It also shows the feasibility of producing and obtaining natural water-soluble pigments for potential use in food industries. A strong combined effect (p<0.05) of pH and temperature was associated with maximal red pigment production (2.46 g/L). | Alejandro MéNDEZ Catalina PéREZ Julio Cesar MONTAéZ Gabriela MARTíNEZ Cristóbal Noé AGUILAR | 2011 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2011，12，12： | 4 |
| 2 | Management of Helicobacter pylori infection in Latin America: A Delphi technique-based consensus显示文摘AIM: To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, and basic scientists carried out a structured evaluation of available literature.METHODS: Relevant questions were distributed among the experts, who generated draft statements for consideration by the entire panel. A modified three-round Delphi technique method was used to reach consensus. Critical input was also obtained from representatives of the concerned medical community. The quality of the evidence and level of recommendation supporting each statement was graded according to United States Preventive Services Task Force criteria.RESULTS: A group of ten experts was established. The survey included 15 open-ended questions that were distributed among the experts, who assessed the articles associated with each question. The levels of agreement achieved by the panel were 50% in the first round, 73.3% in the second round and 100% in the third round. Main consensus recommendations included:(1) when available, urea breath and stool antigen test(HpSA) should be used for non-invasive diagnosis;(2) detect and eradicate Helicobacter pylori(H. pylori) in all gastroscopy patients to decrease risk of peptic ulcer disease, prevent o retard progression in patients with preneoplastic lesions, and to prevent recurrence in patients treated for gastric cancer;(3) further investigate implementation issues and health outcomes of H. pylorieradication for primary prevention of gastric cancer in high-risk populations;(4) prescribe standard 14-d triple therapy or sequential therapy for first-line treatment;(5) routinely assess eradication success post-treatment in clinical settings; and(6) select second- and third-line therapies according to antibiotic susceptibility testing.CONCLUSION: These achievable steps toward better region-specific management can be expected to improve clinical health outcomes. | Antonio Rollan Juan Pablo Arab M Constanza Camargo Roberto Candia Paul Harris Catterina Ferreccio Charles S Rabkin Juan Cristóbal Gana Pablo Cortés Rolando Herrero Luisa Durán Apolinaria García Claudio Toledo Alberto Espino Nicole Lustig Alberto Sarfatis Catalina Figueroa Javier Torres Arnoldo Riquelme | 2014 | World Journal of Gastroenterology2014，20，31： | 2 |
| 3 | Two-year results of renal transplantation in kidney recipients from > or = 65 -year-old deceased donors: a French region experience 显示文摘 | Mzoughi S Albano L Criste M | 2007 | Transplant Proc2007，39，8： | 1 |
| 4 | Treatment of acute distal femur fractures 显示文摘 | Crist B D Dellarocc G J Murtha Y M | 2010 | Orthopedics2010，31，7： | 1 |
| 5 | Pilon fractures : ad- vances in surgical management 显示文摘 | Crist BD Khazzam M Murtha YM | 2011 | J Am Acad Orthop Surg2011，19，10： | 1 |
| 6 | Pilon fractures : advances in surgical management显示文摘 | Crist BD Khazzam M Murtha YM | 2011 | J Am Acad Orthop Surg2011，19，： | 1 |
| 7 | Learning to control a brain-machine interface for reaching and grasping by primates显示文摘 | Carmena J M Lebedev M A Crist R E | 2003 | PLoS Biology2003，1，2： | 1 |
| 8 | Kangaroo mother care and the bonding hypothesis 显示文摘 | TESSIER R CRIST()N M VELEZ S | 1998 | Pediatrics1998，102，2： | 1 |
| 9 | Optimal treatment of femoral neck fracture according to patient's physiologic age : an evidence-based review显示文摘 | Lowe JA Crist BD Bhandari M | 2010 | Orthop Clin North Am2010，41，2： | 1 |
| 10 | Effects of physical exercise for elderly patients with physical impairments显示文摘 | THOMPSON R CRIST D MARSH M | 1988 | J Am Geriatr Soc1988，，36： | 1 |
| 11 | Environmental and economic costs of soil erosion and conservation benefits 显示文摘 | PIMENTEL D HARVEY C RESOSUDARMO P SINCLAIR K KURZ D MCNAIR M CRIST S SHPRITZ L FITTON L SAFFOURI R BLAIR R A | 1995 | Science1995，267，： | 1 |
| 12 | Common musculoskeletal tumors of childhood and adolescence显示文摘 | ARNDT C A CRIST W M | | 0，，05： | 1 |
| 13 | Optimal treatment of femoral neck fractures according to patient physiologic age : an evidence - based review显示文摘 | Lowe JA Crist BD Bhandari M | 2010 | Orthop Clin North Am2010，41，2： | 1 |
| 14 | Pilon fractures: advances in surgical management显示文摘 | Crist BD Khazzam M Murtha YM Della Rocca GJ | 2011 | J Am Acad Orthop Surg2011，19，10： | 1 |
| 15 | Forest moth taxa as indicators of lepidopteran richness and habitat disturbance: a preliminary assessment 显示文摘 | SUMMERVILLE K S RITTER L M CRIST T O | 2004 | Biological Conservation2004，116，1： | 1 |
| 16 | Optimal treatment of femoral neck fractures according to patient's physiologic age:an evidence- based review显示文摘 | Lowe JA Crist BD Bhandari M | 2010 | Orthop Clin North Am2010，41，2： | 1 |
| 17 | Clinical and Biologic Relevance of Immunologic Marker Studies in Childhood Acute Lymphoblastic Leukemia显示文摘 | Pui C H Behm F G Crist W M | 1993 | Blood1993，82，2： | 1 |
| 18 | Reducing the time of sperm-oocyte interaction in human in-vitro fertilization improves the implantation rate显示文摘 | Gianaroli L Cristing Magli M Ferraretti AP | | 0，，01： | 1 |
| 19 | Monoclonal antibody characterization of surface antigens in childhoocl T cell lym\phoid malignancies显示文摘 | Crist WM Metzgar R | 1983 | Blood1983，61，： | 1 |
| 20 | Cumulative effects of roads and logging on landscape structure in the San Juan Mountains,Colorado显示文摘 | McGarigal K Romme W H Crist M | 2001 | Landscape Ecology2001，16，： | 1 |
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