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11篇 您的检索式:作者名="Cruceru"
    题名 作者 年代 出处 被引量
1Cancer stem cells: Involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics显示文摘Pancreatic cancer is one of the most aggressive and lethal malignancies. Despite remarkable progress in understanding pancreatic carcinogenesis at the molecular level, as well as progress in new therapeutic approaches, pancreatic cancer remains a disease with a dismal prognosis. Among the mechanisms responsible for drug resistance, the most relevant are changes in individual genes or signaling pathways and the presence of highly resistant cancer stem cells(CSCs). In pancreatic cancer, CSCs represent 0.2%-0.8% of pancreatic cancer cells and are considered to be responsible for tumor growth, invasion, metastasis and recurrence. CSCs have been extensively studied as of late to identify specific surface markers to ensure reliable sorting and for signaling pathways identified to play a pivotal role in CSC self-renewal. Involvement of CSCs in pancreatic cancer pathogenesis has also highlighted these cells as the preferential targets for therapy. The present review is an update of the results in two main fields of research in pancreatic cancer, pathogenesis and therapy, focused on the narrow perspective of CSCs.Cristiana Pistol Tanase Ana Iulia Neagu Laura Georgiana Necula Cristina Mambet Ana-Maria Enciu Bogdan Calenic Maria Linda Cruceru Radu Albulescu 2014World Journal of Gastroenterology2014,20,31:4
2Novel concept ofcomposite phase change material wall system foryear-round thermal energy savings显示文摘DIACONU B M CRUCERU M 2010Energy andBuildings2010,42,10:1
3Novel concept of composite phase change material wall system for year-round thermal ener- gy savings显示文摘Bogdan M Diaconu Cruceru M H 2010Energy and Buildings2010,42,:1
4Anti-cancer Therapies in High Grade Gliomas显示文摘Cristiana Pistol Tanase Ana-Maria Enciu Simona Mihai Ana Iulia Neagu Bogdan Calenic Maria Linda Cruceru 2013Current Proteomics2013,,:1
5Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms显示文摘Maria Linda Cruceru Monica Neagu Jean‐Baptiste Demoulin Stefan N. Constantinescu 2013J Cell Mol Med2013,,10:1
6Therapy targets in glio- blastoma and cancer stem cells: lessons from haematopoietic neo- plasms显示文摘Cruceru ML Neagu M Demoulin JB 2013J Cell Mol Med2013,17,10:1
7Novel concept of com-posite phase change material wall system for year-round ther-mal energy savings 显示文摘Diaconu Bogdan M Cruceru Mihai 2010Energy and Buildings2010,42,10:1
8Novel concept of composite phase change material wall system for year-round thermal energy savings 显示文摘Bogdan M Diaconu Cruceru M H 2010Energy Buildings2010,42,10:1
9Novel concept of compos- ite phase change material wall system for year-round thermal energy savings 显示文摘Diaconu B M Cruceru M 2010Energy and Buildings2010,42,10:1
10Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms 显示文摘Cruceru ML Neagu M Demoulin JB 2013J Cell Mol Med2013,17,10:1
11Novel concept of composite phase change material wall system for year-round thermal energy savings显示文摘DIACONU B M CRUCERU M 2010Energy and Buildings2010,,42:1
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