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| 1 | Inflammatory bowel disease serology in Asia and the West显示文摘AIM:To study serological antibodies in Caucasians and Asians,in health and inflammatory bowel disease(IBD),in Australia and Hong Kong(HK).METHODS:Anti-glycan antibodies[anti-chitobioside(ACCA),anti-laminaribioside(ALCA)],and anti-mannobioside(AMCA),anti-Saccharomyces cervisiae(gASCA);and atypical perinuclear anti-neutrophil cytoplasmic antibody(pANCA)were tested in IBD patients,their unaffected relatives,and healthy controls in Australia and HK(China).Antibody status(positive or negative)and titre was compared between subjects of different geography,ethnicity and disease state.RESULTS:Ninety subjects were evaluated:21 Crohn’s disease(CD),32 ulcerative colitis(UC),29 healthy controls,and 8 IBD patient relatives.Forty eight subjects were Australian(29 Caucasian and 19 ethnic Han Chinese)and 42 were from HK(all Han Chinese).Caucasian CD patients had a significantly higher antibody prevalence of gASCA(67%vs 3%,P<0.001),ALCA(44%vs 6%,P=0.005),and AMCA(67%vs 15%,P=0.002),whereas HK CD patients had a higher prevalence of only AMCA(58%vs 25%,P=0.035),when compared with UC and healthy subjects in both countries.Caucasian CD had significantly higher gASCA prevalence(67%vs 0%,P<0.001)and titre(median59 vs 9,P=0.002)than HK CD patients.Prevalence and titres of ALCA,ACCA and AMCA did not differ between CD in the two countries.Presence of at least one antibody was higher in Caucasian than HK CD patients(100%vs 58%,P=0.045).pANCA did not differ between countries or ethnicity.CONCLUSION:Serologic CD responses differ between HK Asian and Australian Caucasian patients.Different genetic,environmental or disease pathogenic factors may account for these differences. | Lani Prideaux Michael A Kamm Peter De Cruz Daniel R van Langenberg Siew C Ng Iris Dotan | 2013 | World Journal of Gastroenterology2013，19，37： | 10 |
| 2 | Inflammatory bowel disease in Asia: A systematic review显示文摘 | Lani Prideaux Michael A Kamm Peter P De Cruz Francis K L Chan Siew C Ng | 2012 | Journal of Gastroenterology and Hepatology2012，，8： | 5 |
| 3 | HFE,MTHFR,and FGFR4 genes polymorphisms and breast cancer in Brazilianwomen显示文摘 | Batschauer AP Cruz NG Oliveira VC | 2011 | Mol Cell Biochem2011，357，12： | 1 |
| 4 | Serological antibodies in inflammatory bowel disease : a systematic review 显示文摘 | Pfideanx L De Cruz P Ng SC | 2012 | Inflamm Bow- el Dis2012，18，7： | 1 |
| 5 | Serological antibodies in inflammatory bowel disease:a systematic review显示文摘 | Prideaux L De Cruz P Ng SC | 2012 | Inflamm Bowel Dis2012，18，7： | 1 |
| 6 | Tensile strength of orthodontic brackets bonded directly to fluorotic and nonfluorotic teeth: an invitro comparative study显示文摘 | Ng'anga P M OGAARD B CRUZ R | 1992 | American Journal of Orthodontics and Dent Facial Orthopedics1992，102，： | 1 |
| 7 | The linkage between inflammation and Type 2 diabetes mellitus显示文摘 | Cruz NG Sousa LP Sousa MO | 2013 | Diabetes Res Clin Pract2013，99，2： | 1 |
| 8 | HFE,MTHFR,and FGFR4 genes polymorphisms and breast cancer in Brazilian women显示文摘 | Batschauer AP Cruz NG Oliveira VC | 2011 | Mol Cell Biochem2011，357，12： | 1 |
| 9 | Inflammatory bowel disease in Asia: A systematic review显示文摘 | Lani Prideaux Michael A Kamm Peter P De Cruz Francis K L Chan Siew C Ng | 2012 | Journal of Gastroenterology and Hepatology2012，，8： | 1 |
| 10 | Serological antibodies in inflammatory bowel disease: A systematic review显示文摘 | Lani Prideaux Peter De Cruz Siew C. Ng Michael A. Kamm | 2011 | Inflamm Bowel Dis2011，，7： | 1 |
| 11 | Serological antibodies in inflammatory bowel disease:a systematic review显示文摘 | Prideaux L De Cruz P Ng SC | 2012 | Inflamm Bowel Dis2012，18，7： | 1 |
| 12 | Tensile strength of orthodontic brackets bonded directly to fluorotie and nonfluorotic teeth: An in vitro comparative study显示文摘 | Ng'ang'a PM Ogaard B Cruz R | 1992 | Am J Orthod Dentofacial Orthop1992，102，3： | 1 |
| 13 | HFE,MTHFR,and FGFR4 genes polymorphisms and breast cancer in Brazilian women显示文摘 | Batschauer AP Cruz NG Oliveira VC | | 0，，1： | 1 |
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