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| 1 | Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo显示文摘The hepatic sinusoids are lined by a unique population of hepatic sinusoidal endothelial cells (HSEC), which is one of the first hepatic cell populations to come into contact with blood components. However, HSEC are not simply barrier cells that restrict the access of blood- borne compounds to the parenchyma. They are func- tionally specialised endothelial cells that have complex roles, including not only receptor-mediated clearance of endotoxin, bacteria and other compounds, but also the regulation of inflammation, leukocyte recruitment and host immune responses to pathogens. Thus understand- ing the differentiation and function of HSEC is critical for the elucidation of liver biology and pathophysiology. This article reviews methods for isolating and studying human hepatic endothelial cell populations using in vitro models. We also discuss the expression and functions of phe- notypic markers, such as the presence of fenestrations and expression of VAP-1, Stabilin-1, L-SIGN, which can be used to identify sinusoidal endothelium and to permit discrimination from vascular and lymphatic endothelial cells. | PF Lalor SM Curbishley S Shetty DH Adams | 2006 | World Journal of Gastroenterology2006，12，34： | 11 |
| 2 | Immunology of the gut and liver:a love/hate relationship 显示文摘 | ADAMS DH EKSTEEN B CURBISHLEY SM | 2008 | Gut2008，57，： | 1 |
| 3 | Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function显示文摘 | Lai WK Curbishley SM Goddard S | 2007 | J Hepatol2007，47，3： | 1 |
| 4 | Reactive oxygen species mediate human hepatocyte injury during hypoxia/reoxygenation 显示文摘 | Bhogal RH Curbishley SM Weston C J | 2010 | Liver Transpl2010，16，11： | 1 |
| 5 | Assessment of creep crack growth in dissimilar metal welds 显示文摘 | BUDDEN P J CURBISHLEY L | 2000 | Nuclear Engineering and Design2000，197，： | 1 |
| 6 | Role for hedgehog path- way in regulating growth and function of invariant NKT cells 显示文摘 | Syn WK Witek RP Curbishley SM | 2009 | Eur J hnmunol2009，39，7： | 1 |
| 7 | Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function显示文摘 | Lai WK Curbishley SM Goddard S | 2007 | J Hepatol2007，47，3： | 1 |
| 8 | A new approach to isolation and culture of human Kupffer cells显示文摘 | Alabraba E B Curbishley S M LaiWK | | 0，，1： | 1 |
| 9 | Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function显示文摘 | Lai WK Curbishley SM Goddard S | 2007 | J Hepatol2007，47，3： | 1 |
| 10 | Immunology of the gut and liver: a love/hate relationship 显示文摘 | ADAMS D H EKSTEEN B CURBISHLEY S M | 2008 | Gut2008，57，6： | 1 |
| 11 | Reactive oxygen spe- cies mediate human bepatocyte injury during bypoxia/reoxygenation 显示文摘 | Bhogal RH Curbishley SM Weston CJ | 2010 | Liver Transpl2010，，16： | 1 |
| 12 | Reactive oxygen species mediate human hepatocyte injury during hypoxia/reoxygenation显示文摘 | Bhogal RH Curbishley SM Weston CJ | 2010 | Liver Transpl2010，16，11： | 1 |
| 13 | Epithelialinflammation is associated with CCL28 production and therecruitment of regulatory T cells expressing CCR10 显示文摘 | Eksteen B Miles A Curbishley SM | 2006 | J Immunol2006，177，59： | 1 |
| 14 | Expanded Human Blood-DerivedγδT Cells Display Potent Antigen-Presentation Functions显示文摘 | Khan MW Curbishley SM Chen HC | 2014 | Front Immunol2014，5，： | 1 |
| 15 | Reactive oxygen species mediate human hepatocyte injury during hypoxia/reoxygenation显示文摘 | Bhogal RH Curbishley SM Weston CJ | | 0，，： | 1 |
| 16 | Assessment of creep crackgrowth in dissimilar metal welds显示文摘 | BUDDEN P J CURBISHLEY I | 2000 | Nuclear Engineeringand Design2000，197，： | 1 |
| 17 | Assessment of creep crack growth in dissimilar metal welds显示文摘 | BUDDEN P J CURBISHLEY I | 2000 | Nuclear Engineering and Design2000，197，： | 1 |
| 18 | Epithelial inflam-mation is associated with CCL28 production and the recruit-ment of regulatory T cells expressing CCR10显示文摘 | Eksteen B Miles A Curbishley SM etal | 2006 | J Immunol2006，177，： | 1 |
| 19 | Assessment of Creep Crack Growth in Dissimilar Metal Welds 显示文摘 | Budden P J Curbishley I | 2000 | Nuclear Engineering and Design2000，197，： | 1 |
| 20 | Reactive oxygen spe-cies mediate human hepatocyte injury during hypoxia/reoxygen-ation显示文摘 | Bhogal RH Curbishley SM Weston CJ | | 0，，11： | 1 |
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