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| 1 | Comparison of two nutritional assessment methods in gastroenterology patients显示文摘AIM:To investigate and compare efficacy and differences in the nutritional status evaluation of gastroenterology patients by application of two methods:subjective global assessment(SGA) and nutritional risk index(NRI).METHODS:The investigation was performed on 299 hospitalized patients,aged 18-84 years(average life span 55.57 ± 12.84),with different gastrointe-stinal pathology,admitted to the Department of Gastroenterohepatology,Clinical and Hospital Center 'Bezanijska Kosa' during a period of 180 d.All the patients,after being informed in detail about the study and signing a written consent,underwent nutritional status analysis,which included two different nutritional indices:SGA and NRI,anthropometric parameters,bioelectrical impedance analysis,and biochemical markers,within 24 h of admission.RESULTS:In our sample of 299 hospitalized patients,global malnutrition prevalence upon admission varied from 45.7% as assessed by the SGA to 63.9% by NRI.Two applied methods required different parameters for an adequate approach:glucose level(5.68 ± 1.06 mmol/L vs 4.83 ± 1.14 mmol/L,F = 10.63,P = 0.001);body mass index(26.03 ± 4.53 kg/m2 vs 18.17 ± 1.52 kg/m2,F = 58.36,P < 0.001);total body water(42.62 ± 7.98 kg vs 36.22 ± 9.32 kg,F = 7.95,P = 0.005);basal metabolic rate(1625.14 ± 304.91 kcal vs 1344.62 ± 219.08 kcal,F = 9.06,P = 0.003) were very important for SGA,and lymphocyte count was relevant for NRI:25.56% ± 8.94% vs 21.77% ± 10.08%,F = 11.55,P = 0.001.The number of malnourished patients rose with the length of hospital stay according to both nutritional indices.The discriminative function analysis(DFA) delineated the following parameters as important for prediction of nutritional status according to SGA assessment:concentration of albumins,level of proteins,SGA score and body weight.The DFA extracted MAMC,glucose level and NRI scores were variables of importance for the prediction of whether admitted patients would be classif ied as well or malnourished.CONCLUSION:SGA showed higher sensitivity to predictor factors.Assessment of nutritional status requires a multidimensional approach,which includes different clinical indices and various nutritional param eters. | Branka F Filipovi Milan Gaji Nikola Milini Branislav Milovanovi Branislav R Filipovi Mirjana Cvetkovi Nela ibali | 2010 | World Journal of Gastroenterology2010，16，16： | 9 |
| 2 | Vascularization and osteogenesis in ectopically implanted bone tissue-engineered constructs with endothelial and osteogenic differentiated adipose-derived stem cells显示文摘BACKGROUND A major problem in the healing of bone defects is insufficient or absent blood supply within the defect.To overcome this challenging problem,a plethora of approaches within bone tissue engineering have been developed recently.Bearing in mind that the interplay of various diffusible factors released by endothelial cells(ECs)and osteoblasts(OBs)have a pivotal role in bone growth and regeneration and that adjacent ECs and OBs also communicate directly through gap junctions,we set the focus on the simultaneous application of these cell types together with platelet-rich plasma(PRP)as a growth factor reservoir within ectopic bone tissue engineering constructs.AIM To vascularize and examine osteogenesis in bone tissue engineering constructs enriched with PRP and adipose-derived stem cells(ASCs)induced into ECs and OBs.METHODS ASCs isolated from adipose tissue,induced in vitro into ECs,OBs or just expanded were used for implant construction as followed:BPEO,endothelial and osteogenic differentiated ASCs with PRP and bone mineral matrix;BPUI,uninduced ASCs with PRP and bone mineral matrix;BC(control),only bone mineral matrix.At 1,2,4 and 8 wk after subcutaneous implantation in mice,implants were extracted and endothelial-related and bone-related gene expression were analyzed,while histological analyses were performed after 2 and 8 wk.RESULTS The percentage of vascularization was significantly higher in BC compared to BPUI and BPEO constructs 2 and 8 wk after implantation.BC had the lowest endothelial-related gene expression,weaker osteocalcin immunoexpression and Spp1 expression compared to BPUI and BPEO.Endothelial-related gene expression and osteocalcin immunoexpression were higher in BPUI compared to BC and BPEO.BPEO had a higher percentage of vascularization compared to BPUI and the highest CD31 immunoexpression among examined constructs.Except Vwf,endothelial-related gene expression in BPEO had a later onset and was upregulated and well-balanced during in vivo incubation that induced late onset of Spp1 expression and pronounced osteocalcin immunoexpression at 2 and 8 wk.Tissue regression was noticed in BPEO constructs after 8 wk.CONCLUSION Ectopically implanted BPEO constructs had a favorable impact on vascularization and osteogenesis,but tissue regression imposed the need for discovering a more optimal EC/OB ratio prior to considerations for clinical applications. | Jelena G Najdanović Vladimir J Cvetković Sanja T Stojanović MarijaĐVukelić-Nikolić Jelena MŽivković Stevo J Najman | 2021 | World Journal of Stem Cells2021，13，1： | 3 |
| 3 | Signless Laplacians of finite graphs显示文摘 | CVETKOVI D ROWLINSON P SIMIC S | 2007 | Linear Algebra and Its Applications2007，423，1： | 1 |
| 4 | Signless Laplaeians of finite graphs显示文摘 | Cvetkovie D Rowlinson P Simie S K | 2007 | Linear Algebra Appl2007，432，： | 1 |
| 5 | Dexrazoxane:a review of its use for cardioprotection during anthracycline chemotherapy显示文摘 | Cvetkovi'c RS Scott LJ | 2005 | Drugs2005，65，7： | 1 |
| 6 | A sharp lower bound for the least eigenvalue of the signless Lapla- cian of a non-bipartite graph显示文摘 | CARDOSO D M CVETKOVI'C D ROWLINSON Peter | 2008 | Linear Algebra and Its Applications2008，429，： | 1 |
| 7 | More about gersgorin-type theorems显示文摘 | Cvetkovie Lj Kostic V | 2004 | PAMM2004，4，1： | 1 |
| 8 | H-Matrix Theory vs Eigenvalue Localization 显示文摘 | CVETKOVI L | 2006 | Numer Algor2006，42，： | 1 |
| 9 | Signless Laplacians of Finite Graphs显示文摘 | Cvetkovi D Rowlinson P | 2007 | Linear Algebra and Its Applications2007，423，1： | 1 |
| 10 | Signless Laplacians of finite graphs显示文摘 | Drago? Cvetkovi? Peter Rowlinson Slobodan K. Simi? | 2007 | Linear Algebra and Its Applications2007，，1： | 1 |
| 11 | Kisspeptin/KISS1R system in breast cancer显示文摘 | Cvetkovi c′D Babwah A V Bhattacharya M | 2013 | J Cancer2013，4，8： | 1 |
| 12 | A survey on integral graphs显示文摘 | BALIńSKA K T CVETKOVI D RADOSAVLJEVI Z | 2002 | Univ Beograd Pull Elektrotehn Fak Ser Mat2002，13，： | 1 |
| 13 | Weighted Generalized inverses of partitioned matrices in Banachiewicz-Schur form显示文摘 | DRAGANA S CVETKOVI C ZHENG B | 2006 | J Appl Math and Computing2006，22，3： | 1 |
| 14 | Dexrazoxane:a review of its use for cardioprotection during anthracycline chemotherapy显示文摘 | Cvetkovi RS Scott LJ | 2005 | Drugs2005，65，7： | 1 |
| 15 | Signless Laplacians of finite graphs显示文摘 | CVETKOVI D ROWLINSON P SIMI S K | 2007 | Linear Algebra Appl2007，432，： | 1 |
| 16 | Eigenvalue bounds for the signless Laplacian显示文摘 | CVETKOVI D ROWLINSON P SIMI S K | 2007 | Pub De L Math2007，81，95： | 1 |
| 17 | Graphs and their speir spectra显示文摘 | CVETKOVI C' D M | 1971 | Univ Beograd Publ Elektrotehn Fak Ser Mat Fiz1971，35，： | 1 |
| 18 | Upscaling discrete fracture network simulations: An alternative to continuum transport models 显示文摘 | Painter S Cvetkovie | 2005 | Water Resources Research2005，41，2： | 1 |
| 19 | Towards a spectral theory of graphs based on the signless Laplacian显示文摘 | CVETKOVI'C D SIMI'C S | 2010 | Linear Algebra Appl2010，，432： | 1 |
| 20 | Dexrazoxane:a review of its use for cardioprotection during anthracycline chemotherapy显示文摘 | Cvetkovi'c RS Scott LJ | 2005 | Drugs2005，65，7： | 1 |
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