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| 1 | Associations of lifestyle and diet with the risk of nasopharyngeal carcinoma in Singapore:a case–control study显示文摘Background: Nasopharyngeal carcinoma(NPC) is a commonly diagnosed cancer in Southeast Asia. Many studies have examined the risk factors for NPC, yet the roles of some risk factors remain inconclusive. The purpose of this study was to examine associations between modifiable lifestyle factors and the risk of NPC in the Singaporean population.Methods: We conducted a case–control study in Singapore with 300 patients and 310 controls who were recruited between 2008 and 2012. Each control was selected and individually matched to each patient based on sex, ethnicity, and age(±5 years). A total of 290 pairs of cases and controls were matched successfully. We examined lifestyle factors such as tobacco smoking, alcohol drinking, various salted and preserved food consumption, and weaning practices.Results: After adjusting for covariates, multivariate analysis showed that those participants who were current smokers and had ever smoked tobacco had a higher risk of NPC than participants who had never smoked, with odds ratios(ORs) of 4.50(95% confidence interval [CI] 2.58–7.86; P < 0.001) and 2.52(95% CI 1.54–4.12; P < 0.001), respectively. Those who consumed salted vegetables at least once a week also showed a significantly increased risk of NPC than those who never or rarely consumed salted vegetables, with an OR of 4.18(95% CI 1.69–10.38; P = 0.002).Conclusion: Smoking(currently and ever-smoked) and consuming salted vegetables once a week or more were lifestyle risk factors for NPC, and changes of these factors for the better may reduce the risk of NPC. | Sook Kwin Yong Tam Cam Ha Ming Chert Richard Yeo Valerie Gaborieau James D.McKay Joseph Wee | 2017 | Chinese Journal of Cancer2017，36，2： | 12 |
| 2 | Translocal subjectivities:Mobility,connection,emotion显示文摘 | Conradson D D.McKay | | 0，，2： | 1 |
| 3 | A new timeframe for the diversification of Japan’s mammals显示文摘 | Bailey D.McKay | 2012 | Journal of Biogeography2012，，： | 1 |
| 4 | 基于微卫星标记的绿背山雀遗传结构分析(英文)显示文摘近些年来,核序列基因和微卫星标记被广泛地应用于物种遗传结构分析,然而,对于两者的有效性我们却知之甚少。本文以绿背山雀(Parus monticolus)为研究对象,探讨核序列基因和微卫星标记在解析物种遗传结构方面的有效性。绿背山雀中部和西南线粒体谱系分支在核序列基因上存在相应的遗传分化,而在微卫星数据上却不存在分化。两个谱系分支在核序列基因上的FST值是微卫星的4倍。我们认为等位基因大小异源同形(size homoplasy)可能是导致微卫星标记无法区分两个谱系分支的主要原因。我们的研究结果表明在探讨物种遗传结构,且当目标种群具有较大的有效种群数量时,核序列基因比微卫星标记具有更强的适用性。绿背山雀各线粒体谱系分支间的 FST值与等位基因数量不存在显著的相关性,该结果表明微卫星标记的有效性与等位基因的数量无关。RST值的变化范围比 FST值大,因此更不利于探讨种群间的遗传分化。与核序列基因相符,微卫星标记同样揭示了台湾支系的遗传独立性。台湾支系与大陆支系间的遗传分化可能属于严格的异域分化过程。 | 王文娟 戴传银 Bailey D.MCKAY 赵娜 李寿先 雷富民 | 2013 | Chinese Birds2013，，2： | 1 |
| 5 | 新加坡的生活方式和饮食习惯与鼻咽癌风险的关系:一项病例对照研究显示文摘背景与目的鼻咽癌(nasopharyngeal carcinoma,NPC)是东南亚地区一种常见的癌症。许多研究已经对NPC的风险因素进行了研究,但一些风险因素的作用仍无定论。本研究旨在探讨新加坡人可改变的生活方式因素与NPC风险之间的关系。方法我们在新加坡进行了一项病例对照研究,在2008年至2012年期间招募了300例患者和310例对照。根据性别、种族和年龄(±5岁)对各例对照进行选择并分别与每一例患者匹配。共有290对病例和对照成功匹配。我们对多个生活方式因素,如吸烟、饮酒、各种腌制和罐头食品消费以及断奶习惯进行了研究。结果调整协变量后多因素分析显示,现行吸烟者和有既往吸烟史的参与者比从未吸烟的参与者患NPC的风险更高,优势比(odds ratios,ORs)分别为4.50 [95%置信区间(confidence interval,CI):2.58–7.86;P <0.001]和2.52(95%CI:1.54–4.12;P <0.001)。每周至少吃1次腌制蔬菜的人也比那些从不或很少食用腌制蔬菜的人表现出NPC风险显著增加,OR值为4.18(95%CI:1.69–10.38;P=0.002)。结论吸烟(现行和经常吸食)和每周1次或多次食用腌制蔬菜是NPC的生活方式风险因素,戒除这些不良因素可以降低NPC的风险。 | Sook Kwin Yong Tam Cam Ha Ming Chert Richard Yeo Valerie Gaborieau James D.McKay Joseph Wee | 2018 | 癌症2018，37，11： | 1 |
| 6 | Leg Extension Strength, Explosive Strength, Muscle Activation, and Growth as Predictors of Vertical Jump Performance in Youth Athletes显示文摘Purpose The purpose of this study was to examine the relationships among leg extension strength,explosive strength,muscle activation,and measurements of growth to predictions of vertical jump performance in youth athletes.Methods Height,body mass,skinfolds,and quadriceps femoris muscle cross-sectional area were measured in 39 sports active children(20 females,19 males,age=12.52±0.62 years old).Peak torque(PT),rate of torque development(RTD),rate of velocity development(RVD),and rate of electromyographic amplitude rise(RER)were measured during isometric and isokinetic leg extensions.PT,RTD,and RVD were expressed in absolute terms and normalized to body mass.Estimated jump height(JH)and peak power(PP)were assessed during static(SJ),counter-movement(CMJ),and drop(DJ)jumps.Results JH exhibited greater correlations with PT normalized to body mass(r=0.387-0.758)than absolute PT(r=0.338-0.417),whereas PP exhibited greater correlations with absolute PT(r=0.368-0.837).Only negligible to moderate relation-ships existed between JH and PP across all jumps(r=0.053-0.605).Over 50%of the variability in PP was predicted in 24 of 30 regression models with absolute muscle strength,muscle activation,and measurements of growth,while only 6 of 30 models predicted more than 50%of the variability in JH.Conclusion Overall,absolute static and dynamic muscle strength,muscle activation,and growth better explained PP meas-ured during vertical jumps than estimated JH. | Zachary M.Gillen Marni E.Shoemaker Brianna D.McKay Nicholas A.Bohannon Sydney M.Gibson Joel T.Cramer | 2020 | Journal of Science in Sport and Exercise2020，2，4： | 0 |
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