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| 1 | Composer-Science: a se- mantic service based framework for workflow composition in e-Sci- ence projects显示文摘 | da SILVA L M BRAGA R CAMPOS F | 2012 | Information Sciences2012，186，1： | 1 |
| 2 | Inverted or ganic photovoltaic devices with high efficiency and sta- bility based on metal oxide charge extraction layers 显示文摘 | Schumann S Da Campo R Illy B | 2011 | Journal of Materials Chemistry2011，21，7： | 1 |
| 3 | Cadmium uptake by hydroxyapatite synthesized in dif- ferent conditions and submitted to thermal treatment 显示文摘 | Da Rocha N C C De Campos R C Rossi A M | 2002 | Environmental Science and Technology2002，36，7： | 1 |
| 4 | Low dose estrogen is as effective as high-dose treatment in rats with postmenopausal hypertension 显示文摘 | Campos C Sartorio C L Casali K R Fernandes R O Llesuy S da Rosa Araujo A S | 2014 | J Cardiovasc Pharmaeol2014，63，： | 1 |
| 5 | CdS nanocomposites assembled in porous phos- phate heterostructures for fingerprint detection 显示文摘 | Algarra M Jimenez-Jimenez J Moreno-Tost R Campos B B Esteves da Silva JCG | 2011 | Optical Materials2011，33，6： | 1 |
| 6 | Recrystallisation of mesoporous SBA-15 into microporous ZSM-5显示文摘 | Campos A A Dimitrov L da Silva C R | 2006 | Microporous and MesoporousMaterials2006，95，： | 1 |
| 7 | Recrystallisation of mesoporous SBA-15 into microporous ZSM-5 显示文摘 | Campos A A Dimitrov L Da Silva C R | 2006 | Microporous and Mesoporous Materials2006，95，123： | 1 |
| 8 | A simple methodology for the determination of fatty acid composition in edible oils through 1H NMR spectroscopy显示文摘 | BARISON A DA S C CAMPOS F R | 2010 | Magnetic Resonance in Chemistry2010，48，8： | 1 |
| 9 | IgC- anti IgA subclasses in common variable imunodeficiency and association with severe adverse reactions lo intravenous immunoglob ulin therapy显示文摘 | de Albuquerque Campos R Sato MN da Silvarte AJ | 2000 | J Clin Immunol2000，20，1： | 1 |
| 10 | 显示文摘 | Campos A A Dimitrov L da Silva C R | 2006 | Microporous and Mesoporous Materials2006，95，13： | 1 |
| 11 | Characterization of naphthenic acid singly charged noncovalent dimers and their dependence on the accumulation time within a hexapole in fourier transform ion cyclotron resonance mass spectrometry 显示文摘 | DA CAMPO R BARROW M P SHEPHERD A G SALISBURY M DERRICK P J | 2009 | Energy Fuels2009，23，11： | 1 |
| 12 | Real-world treatment patterns and disease control over one year in patients with inflammatory bowel disease in Brazil显示文摘BACKGROUND Crohn’s disease(CD)and ulcerative colitis(UC)are inflammatory bowel diseases(IBDs)with a remission-relapsing presentation and symptomatic exacerbations that have detrimental impacts on patient quality of life and are associated with a high cost burden,especially in patients with moderate-to-severe disease.The Real-world Data of Moderate-to-Severe Inflammatory Bowel Disease in Brazil(RISE BR)study was a noninterventional study designed to evaluate disease control,treatment patterns,disease burden and health-related quality of life in patients with moderate-to-severe active IBD.We report findings from the prospective follow-up phase of the RISE BR study in patients with active UC or CD.AIM To describe the 12-mo disease evolution and treatment patterns among patients with active moderate-to-severe IBD in Brazil.METHODS This was a prospective,noninterventional study of adult patients with active Crohn’s disease(CD:Harvey-Bradshaw Index≥8,CD Activity Index≥220),inadequate CD control(i.e.,calprotectin>200μg/g or colonoscopy previous results),or active ulcerative colitis(UC:Partial Mayo score≥5).Enrollment occurred in 14 centers from October 2016 to February 2017.The proportion of active IBD patients after 9-12 mo of follow-up,Kaplan-Meier estimates of the time to mild or no activity and a summary of treatment initiation,discontinuation and dose changes were examined.RESULTS The study included 118 CD and 36 UC patients,with mean±SD ages of 43.3±12.6 and 44.9±16.5 years,respectively.The most frequent drug classes at index were biologics for CD(62.7%)and 5-aminosalicylate derivates for UC patients(91.7%).During follow-up,65.3%of CD and 86.1%of UC patients initiated a new treatment at least once.Discontinuations/dose changes occurred in 68.1%of CD patients[median 2.0(IQR:2-5)]and 94.3%of UC patients[median 4.0(IQR:3-7)].On average,CD and UC patients had 4.4±2.6 and 5.0±3.3 outpatient visits,respectively.The median time to first mild or no activity was 319(IQR:239-358)d for CD and 320(IQR:288-358)d for UC patients.At 9-12 mo,22.0%of CD and 20.0%of UC patients had active disease.CONCLUSION Although a marked proportion of active IBD patients achieved disease control within one year,the considerable time to achieve this outcome represents an unmet medical need of the current standard of care in a Brazilian real-world setting. | Ligia Yukie Sassaki Sender J Miszputen Roberto Luiz Kaiser Junior Wilson R Catapani Mauro Bafutto António S Scotton Cyrla Zaltman Julio Pinheiro Baima Hagata S Ramos Mikaell Alexandre Gouvea Faria Carolina D Gonçalves Isabella Miranda Guimaraes Cristina Flores Heda M B S Amarante Rodrigo Bremer Nones JoséMiguel Luz Parente Murilo Moura Lima Júlio Maria Chebli Maria de Lourdes Abreu Ferrari Julia F Campos Maria G P Sanna Odery Ramos Rogério Serafim Parra Jose J R da Rocha Omar Feres Marley R Feitosa Rosana Fusaro Caratin Juliana Tosta Senra Genoile Oliveira Santana | 2021 | World Journal of Gastroenterology2021，27，23： | 0 |
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