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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | System Studies on CO2 Abatement From Power Plant 显示文摘 | Goldthorpe S H Cross P J I Davison J E | 1992 | Energy Convers Mgmt1992，33，58： | 1 |
| 3 | Investigation of the curing variables of asphalt-rubber binder 显示文摘 | Billiter T C Chun J S Davison R R | 1997 | Pet Sci Technol1997，15，： | 1 |
| 4 | Genetic exchange between bacteria in the environment 显示文摘 | Davison J | 1999 | Plasmid1999，42，2： | 1 |
| 5 | The path forward for biofuels and biomaterials 显示文摘 | RAGAUSKAS A J WILLIAMS C K DAVISON B H | 2006 | Science2006，311，5760： | 1 |
| 6 | MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma 显示文摘 | Szafranska AE Davison TS John J | 2007 | Oncogene2007，26，30： | 1 |
| 7 | The family Parvoviridae显示文摘 | Cotmore S F Agbandje-McKenna M Chiorini J A Mukha D V Pintel D J Qiu J Soderlund-Venermo M Tattersall P Tijssen P Gatherer D Davison A J | 2014 | Arch Virol2014，159，5： | 1 |
| 8 | Serelaxin,recombinant human relaxin-2,for treatment of acute heart failure(RELAX-AHF):a randomised,placebo-controlled trial显示文摘 | TEERLINK J R COTTER G DAVISON B A | 2013 | Lancet2013，381，： | 1 |
| 9 | Impact of personal and cultural factors on knowledge sharing in China显示文摘 | Huang Q Davison R M Gu J B | 2008 | Asia Pacific Journalof Management2008，25，3： | 1 |
| 10 | Rotational Stiffness Characteristics of Steel Beam-to-column Connections显示文摘 | Davison J B Kirby P A Nethercot D A | 1987 | J of Construct Steel Research1987，，8： | 1 |
| 11 | Topics in herpesvirus genomics and evolution 显示文摘 | McGeoch D J Rixon F J Davison A J | 2006 | Virus Research2006，117，1： | 1 |
| 12 | MicroR NA expression alterations are linked to tumorigenesis and nonneoplastic processes in pancreatic ductal adenocarcinoma显示文摘 | Szafranska A Davison T John J | 2007 | Oncogene2007，，30： | 1 |
| 13 | Active matching for visual tracking显示文摘 | Chli M Davison A J | 2009 | Robotics and Autonomous Systems2009，57，12： | 1 |
| 14 | Displacement measurement in studies of steel T-stub connections显示文摘 | Spyrou S Davison J B | 2001 | Journal of Constructional Steel Research2001，57，： | 1 |
| 15 | A method for simplifying linear dynamic systems显示文摘 | Davison E J | 1966 | IEEE Transation on Automatic Control1966，，11： | 1 |
| 16 | Genomic instability in Solanum tuberosum × Solarium kurtzianum interspecific hybrids 显示文摘 | Marfil C F Masuelli R W Davison J | 2006 | Genome2006，49，： | 1 |
| 17 | Genetic exchange between bacteria in the environment 显示文摘 | DAVISON J | 1999 | Plasmid1999，42，： | 1 |
| 18 | The Path Forward for Biofuels and Biomaterials 显示文摘 | Arthur J Ragauskas Charlotte K Williams Brian H Davison | 2006 | Science2006，311，： | 1 |
| 19 | Chronic kidney disease in pregnancy显示文摘 | Williams D Davison J | | 0，，7637： | 1 |
| 20 | MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma显示文摘 | Szafranska AE Davison TS John J | 2007 | Oncogene2007，26，： | 1 |
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