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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010，16，31： | 10 |
| 2 | ln-Situ high-resolutian measurements of fluxes of Ni,Cu,Fe,and Mn and concentrations of Zn and Cd in porewaters by DGT显示文摘 | Zhang H Davison W Miller S | 1995 | Geochimica et Cosmochimica Acta1995，59，20： | 1 |
| 3 | System Studies on CO2 Abatement From Power Plant 显示文摘 | Goldthorpe S H Cross P J I Davison J E | 1992 | Energy Convers Mgmt1992，33，58： | 1 |
| 4 | Investigation of the curing variables of asphalt-rubber binder 显示文摘 | Billiter T C Chun J S Davison R R | 1997 | Pet Sci Technol1997，15，： | 1 |
| 5 | Hormone replacement therapy: current controversies 显示文摘 | Davison S Davis S R | 2003 | Clin Endoerinol (Oxf)2003，58，3： | 1 |
| 6 | Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial显示文摘 | John R Teerlink Gad Cotter Beth A Davison G Michael Felker Gerasimos Filippatos Barry H Greenberg Piotr Ponikowski Elaine Unemori Adriaan A Voors Kirkwood F Adams Maria I Dorobantu Liliana R Grinfeld Guillaume Jondeau Alon Marmor Josep Masip Peter S Pang | 2013 | The Lancet . 2013 (9860)2013，，9860： | 1 |
| 7 | A quantitative duplex PCR technique for measuring amounts of cell - associated Marek ' s disease virus: differences in two populations of lymphoma cells显示文摘 | Burgess S C Davison T F | 1999 | Journal of Virological Methods1999，82，： | 1 |
| 8 | Diffusion coefficients of metals and metal complexes in hydrogels used in diffusive gradients in thin films显示文摘 | Scally S Davison W Zhang H | 2006 | Analytica Chimica Acta2006，558，12： | 1 |
| 9 | Determination of cellulose in textile fibers 显示文摘 | SMITH B F DAVISON S SMITH F | 1962 | Textile Research Journal1962，32，1： | 1 |
| 10 | The family Parvoviridae显示文摘 | Cotmore S F Agbandje-McKenna M Chiorini J A Mukha D V Pintel D J Qiu J Soderlund-Venermo M Tattersall P Tijssen P Gatherer D Davison A J | 2014 | Arch Virol2014，159，5： | 1 |
| 11 | Counting absolute numbers of specific leukocyte subpopulations in avian whole blood using a single-step flow eytometric technique: comparison of two inbred lines of chickens显示文摘 | Burgess S C Davison T F | 1999 | Immunol Methods1999，297，12： | 1 |
| 12 | Tissue expander infections in children:look beyond the expander pocket显示文摘 | DAVISON S P MANDERS E K | 1999 | Ann Plast Surg1999，43，5： | 1 |
| 13 | In the eyes of the beholder: a non-self-report measure of workplace deviance显示文摘 | STEWART S M BING M N DAVISON H K | 2009 | Journal of Applied Psychology2009，94，1： | 1 |
| 14 | Androgen levels in adult females: changes with age, menopause, and oophorectomy显示文摘 | Davison S L Bell R Donath S | 2005 | J Clin Endocrinol Metab2005，90，7： | 1 |
| 15 | Stereotactic radiosurgery:the patient's experience显示文摘 | Menkes D B Davison M P Costello S A | | 0，，11： | 1 |
| 16 | Development of infectious transcripts and genome manipulation of Black queen-cell virus of honey bees显示文摘 | Benjeddou M Leat N Allsopp M Davison S | 2002 | J Gen Virol2002，83，： | 1 |
| 17 | A gene expression map of Arabidopsis thaliana development 显示文摘 | Sehmid M Davison T S Henz S R | 2005 | Nat Genet2005，37，： | 1 |
| 18 | Displacement measurement in studies of steel T-stub connections显示文摘 | Spyrou S Davison J B | 2001 | Journal of Constructional Steel Research2001，57，： | 1 |
| 19 | Minimally invasive surgical treatment of lumbar spinal stenosis: Two-year follow-up in 54 patients显示文摘 | Palmer S Davison L | 2012 | Surg Neurol Int2012，3，： | 1 |
| 20 | Advance care planning in patients with chronic kidney disease显示文摘 | Davison S N | 2012 | Seminars in Dialysis2012，25，6： | 1 |
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