|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 2 | Corrosion behavior of Mg-Y alloy in NaCl aqueous solution | Xin Zhang a,b,c,Kui Zhang a,Xia Deng a,Hongwei Li b,c,Yongjun Li a,Minglong Ma a,Ning Li b,c,Yanlong Wang b,c a State Key Laboratory for Fabrication and Processing of Nonferrous Metals,Beijing General Research Institute for Nonferrous Metals,Beijing 100088,China b Beijing Engineering Research Center for Advanced Manufacturing and Evaluation of Special Vehicle Parts,Beijing 100072,China c Center of Technology,Beijing North Vehicle Group Corporation,Beijing 100072,China | 2012 | Progress in Natural Science:Materials International2012，22，2： | 7 |
| 3 | Characterization of two new gene cassettes, aadA5 and dfrA17 显示文摘 | White P A Mclver C J Deng Y | 2000 | FEMS Microbiol Lett2000，182，2： | 2 |
| 4 | Electrochemical behavior of LiMn2O4 and LiCoO2 thin film produced with pulsed laser deposition显示文摘 | Striebel K A Deng C Z Cairns E J | 1996 | J Electrochem Soc1996，143，6： | 1 |
| 5 | Factors affecting Agrobactcrium-mediated transformation and regeneration of sweet orange and citrange 显示文摘 | Yu C H Huang S Chen C X Deng Z A Ling P and Gmitter F O J | 2002 | Plant Cell Tissue and Organ Culture2002，71，： | 1 |
| 6 | Large-pore apertures in a series of metal-organic frameworks显示文摘 | Deng H Grunder S Cordova K E Valente C Furukawa H Hmadeh M Gandara F Whalley A C Liu Z Asahina S Kazumori H O'Keeffe M Terasaki O Stoddart J F Yaghi O M | 2012 | Science2012，336，： | 1 |
| 7 | DNA methyltransferases 1 and 3B are required for hepatitis C virus infection in cell culture显示文摘 | Chen C Pan D Deng A | 2013 | Virology2013，441，1： | 1 |
| 8 | A computeraided system for an optimal moulding conditions design using a simulation-based approach 显示文摘 | LAM Y C BRITTON G A DENG Y M | 2003 | International Journal of Advanced Manufacturing Technology2003，22，： | 1 |
| 9 | Direct removal in the mouse of a floxed neo gene from a three-loxp conditional knockout allele by two novel approaches 显示文摘 | Li C Garrett-Beal L Larson D Wynshaw-Boris A Deng CX | 2001 | Genesis2001，30，1： | 1 |
| 10 | Protease activated re(c)eptor2,a receptor involved in melanosome transfer,is up regulated in human skin by ultraviolet irradiation显示文摘 | Scott G Deng A Rodriguez-Burford C | | 0，，06： | 1 |
| 11 | 显示文摘 | Deng C Camps-Torres J | 1995 | Oncogene1995，11，1： | 1 |
| 12 | Chaotic motion of a horizontal impact pair显示文摘 | Han R P S Luo A C J Deng W | 1995 | Journal of Sound and Vibration1995，181，2： | 1 |
| 13 | Determining the component number of links corresponding to triangular and honeycomb lat- tices 显示文摘 | JIANG L P JINX A DENG K C | 2012 | J Knot Theor Ramif2012，21，2： | 1 |
| 14 | Characteristics of a widespread community cluster of H275Y oseltamivir-resistant A (H1N1) pdm09 influenza in Australia显示文摘 | Hurt A C Hardie K Wilson N J Deng Y M Oshourn M Leang S K Lee R T Iannello P Gehrig N Shaw R Wark P Caldwell N Givney R C Xue L Maurer- Stroh S Dwyer D E Wang B Smith D W Levy A Booy R Dixit R Merritt T Kelso A Dalton C Durrheim D Barr I G | 2012 | J Infect Dis2012，206，2： | 1 |
| 15 | Characterization of gear pumps fabricated by LIGA 显示文摘 | Deng K Dewa A S Ritter D C | 1998 | Microsystem Technologies1998，4，4： | 1 |
| 16 | Fibroblast growth factor receptor 3 is a negative regulator of bone growth显示文摘 | Deng C Wynshaw-Boris A Zhou F | 1996 | Cell1996，84，6： | 1 |
| 17 | Canonical piece-wise-linear represen- tation 显示文摘 | CHUA I O DENG A C | 1988 | IEEETransonCAS1988，35，： | 1 |
| 18 | Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm 显示文摘 | Huang X Zhao Y Wei X Li C Wang A Zhao Q Li W Guo Y Deng L Zhu C Fan D Lu Y Weng Q Liu K Zhou T Jing Y SiL DongG Huang T Lu T Feng Q Qian Q Li J Han B | 2011 | Nature Genetics2011，44，1： | 1 |
| 19 | Rapid analysis of essential oil from Fructus Amomi by pressurized hot water extraction foUowed by solid-phase microextraction and gaschromatography- mass spectrometry显示文摘 | Deng C H Wang A Q Shen S et ol | 2005 | Journal of Pharmaceutical and Biomedical Analysis2005，38，2： | 1 |
| 20 | Bed mixing and heat transfer in a batch loaded rotary kiln显示文摘 | LEGER C B COOK C A CUNDY V A STERLIMG A M DENG X LIGHTY J S | | 0，，02： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员