|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | FibroSURE^(TM) and FibroScan~ in relation to treatment response in chronic hepatitis C virus显示文摘AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interferon-based therapy for 24(genotypes 2/3)or 48(genotype 1)wk.FibroSURE~TM(FS)was assessed at baseline and at week-12 post-treatment follow-up.Baseline biopsy for METAVIR was assessed by a single pathologist.FibroScan~ transient elastogra-phy(TE)was performed during treatment in a patient subset.RESULTS:Two thousand and sixty patients(n = 253 in Asia)were classif ied as METAVIR F0-1(n = 1682)or F2-4(n = 378).For F2-4,FS(n = 2055)had sensitiv-ity and specif icity of 0.87 and 0.61,respectively,with area under the receiver-operating curve of 0.82;corre-sponding values for TE(n = 214)and combined FS/TE(n = 209)were 0.77,0.88 and 0.88,and 0.93,0.68 and 0.88.Overall FS/TE agreement for F2-4 was 71%(κ = 0.41)and higher in Asians vs non-Asians(κ = 0.86 vs 0.35;P < 0.001).Combined FS/TE had 97% accuracy in Asians(n = 33).Baseline FS(0.38 vs 0.51,P < 0.001)and TE(8.0 kPa vs 11.9 kPa,P = 0.006)scores were lower in patients with sustained virological response than in nonresponders,and were maintained through follow-up.CONCLUSION:FS and TE may reliably differentiate mild from moderate-advanced disease,with a potential for high diagnostic accuracy in Asians with chronic HCV. | Keyur Patel Mireen Friedrich-Rust Yoav Lurie Mircea Grigorescu Carol Stanciu Chuan-Mo Lee Eugene R Schiff Dieter Hussinger Michael P Manns Guido Gerken Isabelle Colle Michael Torbenson Erik Pulkstenis G Mani Subramanian John G McHutchison Stefan Zeuzem | 2011 | World Journal of Gastroenterology2011，17，41： | 4 |
| 2 | IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality显示文摘 | Zhang Hong Neuh?fer Patrick Song Liang Rabe Bj?rn Lesina Marina Kurkowski Magdalena U Treiber Matthias Wartmann Thomas Regnér Sara Thorlacius Henrik Saur Dieter Weirich Gregor Yoshimura Akihiko Halangk Walter Mizgerd Joseph P Schmid Roland | 2013 | Journal of Clinical Investigation2013，，3： | 2 |
| 3 | α-Oxo ketene dithioacetals and related compounds: Versatile three earbon synthons显示文摘 | DIETER R K | 1986 | Tetrahedron1986，42，： | 1 |
| 4 | Investigation of aortocoronary artery bypass grafts by muhislice spiral computed tomography with electrocardiographic, gated image reconstruction显示文摘 | Dieter R Stefan U Evelyn W | 2001 | Am J Cardiol2001，88，7： | 1 |
| 5 | Persistent infant crying and hyperactivity problems in middle childhood显示文摘 | Dieter W Patrizia R Sarah W | 2002 | Pediatrics2002，，6： | 1 |
| 6 | Investigation of aortocoronary artery by- pass graft by multislice spiral computed tomography with electrocadiographic, gated image reconstruction显示文摘 | Dieter R Stefan U Evelan W | 2001 | Am J Cardiol2001，88，7： | 1 |
| 7 | Investigation of aortocoronary artery bypass grafts by multislice spiral computed tomograhphy with electrocardiographic,gated image reconstruction显示文摘 | Dieter R Stefan U Evelyn W | 2001 | Am J Cardiol2001，88，7： | 1 |
| 8 | Investigation of aortic coronary artery bypass bu mutislice spiral computed tomography with electocardiographic gated image reconstruction 显示文摘 | Dieter R Stenfan N Evelyn W | 2001 | Am J Cardiol2001，86，7： | 1 |
| 9 | α-Oxo ketenedithloacetalsandrelated compounds : Versatilethree-carbon synthons 显示文摘 | Dieter R K | 1986 | Tetrahedrun1986，42，： | 1 |
| 10 | Genetic parameter estimates for volume from full - sib tests of slash pine 显示文摘 | M J Dieters T L White G R Hodge | 1995 | Can J For Res1995，25，8： | 1 |
| 11 | Atmosphericchemistry of Peroxides : A Review 显示文摘 | Dieter W Gunz Michael R Hoffmann | 1990 | AtmosphericEnvironment1990，24，7： | 1 |
| 12 | Atmosphericchemistry of Peroxides : A Review 显示文摘 | Dieter W Gunz Michael R Hoffmann | 1990 | AtmosphericEnvironment1990，24，7： | 1 |
| 13 | Formation of sequences of cemented layers and hardpans within sulfide - bearing mine tailings显示文摘 | Torsten G Andrea K Dieter R | 2007 | Applied Geochemistry2007，22，1： | 1 |
| 14 | Serum electrolyte changes after cardiopulmonary bypass with Ringer's lactate solution used for hemodilution 显示文摘 | Dieter RA Jr Neville WE Pifarr6 R | 1970 | J Thorac Cardiovasc Surg1970，59，2： | 1 |
| 15 | Investigation of aortic coronary artery bypass bu mutislic spiral computed tomography with electrocardiographic gated image reconstruction 显示文摘 | Dieter R Stenfan N Evelyn W | 2001 | Am J Cardiol2001，86，7： | 1 |
| 16 | Acylation of a- (N-carbamoyl)alkylcuprates and alkyl-oraryl(halo)cuprates 显示文摘 | R Karl Dieter Ram R Sharma | 2003 | Tetrahedron2003，59，： | 1 |
| 17 | Investigation of Aortocoronary Artery Bypass by Multislice Spiral Computed Tomography with Electrocardiographic Gated Image Reconstruction显示文摘 | Dieter R Stefan U Evelyn W | 2001 | Am J Cardiol2001，88，7： | 1 |
| 18 | Functional coupling of cyclooxygenase 1 and 2 to discrete prostanoid synthases in liver macrophages显示文摘 | Dieter P Scheibe R Jakobsson PJ | 2000 | Biochem Biophys Res Commun2000，276，： | 1 |
| 19 | A continuum model for a re-entrant factory显示文摘 | Dieter A Dan M Christian R | 2006 | Operation Research2006，54，5： | 1 |
| 20 | Investigation of aortocoronary artery bypass grafts by multislice spiral computed tomogrraphy with electrocardiographic,gated image recomstruction显示文摘 | Stefan U Evelyn W | 2001 | Am J Cardiol2001，88，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员